Caenorhabditis elegans Maupas (nematode) [CEL]

FULL NAME: Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2


DESCRIPTION:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB6 is part of the clamp element and togther with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).

STRUCTURE SIMILARITY:
Belongs to the archaeal rpoK/eukaryotic RPB6 RNA polymerase subunit family.


RELATED PATHWAY(S):
transcription


Amino acids sequence

        10         20         30         40         50         60
MADEDDYQDM DNDDFVDDNE MEDVIEEDPQ RPDNEDEDDD NVDENFELFD QGKAVPTSEH
        70         80         90        100        110        120
VTTPFMTKYE RARVLGTRAL QIAMGAPVMV ELEGETDPLE IARKELKQRR IPIIVRRYLP
       130
DGSYEDWPTD QLQLADW    

Encoded by rpb-6 gene

FULL NAME: RNA Polymerase II (B) subunit


Nucleic acid sequence

        10         20         30         40         50         60
atggccgatg aggacgatta tcaagatatg gataatgatg atttcgttga cgacaacgaa
        70         80         90        100        110        120
atggaggacg tgatcgaaga agatccacaa cgccctgaca atgaggacga ggacgatgac
       130        140        150        160        170        180
aacgtggacg agaatttcga gcttttcgat caaggaaagg ctgttccgac tagtgagcat
       190        200        210        220        230        240
gtgacaactc cattcatgac aaaatacgaa cgagctcgag ttcttggcac tcgcgctctc
       250        260        270        280        290        300
caaatcgcca tgggagctcc ggttatggtt gaacttgaag gagagaccga tccattggag
       310        320        330        340        350        360
attgctcgca aggagcttaa acaacgccgt atcccgatca ttgtccgccg ctaccttcca
       370        380        390        400        410
gatggatcat acgaagactg gccaaccgat caacttcaac tcgctgattg gtag

Last modification date: Oct. 2, 2011