Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: DNA-directed RNA polymerase II subunit RPB9


DESCRIPTION:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity). Involved in the regulation of transcription elongation.

STRUCTURE SIMILARITY:
Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
Contains 1 TFIIS-type zinc finger.


RELATED PATHWAY(S):
transcription


Amino acids sequence

        10         20         30         40         50         60
MSNFQYCIEC NNMLYPREDK VDRVLRLACR NCDYSEIAAT SKVYRHELQS SNVENTTVSH
        70         80         90        100        110
DASTDPTLPR SDKECPRCHQ HEAVFYQTHS RRGDTMMTLI YVCVHCGFAF EEQ

Encoded by rpb9 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgtcaaatt ttcaatattg tatagaatgc aataatatgc tgtaccctag agaggataaa
        70         80         90        100        110        120
gtggatcgtg ttctgaggct agcttgtcgt aattgtgatt actcagagat cgctgctact
       130        140        150        160        170        180
agtaaagttt atcgccatga gttacaaagc tccaatgtag aaaacacgac ggtcagtcac
       190        200        210        220        230        240
gacgcttcaa cggaccctac tttacctaga tcagacaaag aatgcccgcg ttgtcatcaa
       250        260        270        280        290        300
catgaagcag ttttttatca gactcattct cgtcggggtg atactatgat gactctgatt
       310        320        330        340
tatgtttgcg tacattgtgg atttgctttt gaagaacagt aa 

Last modification date: Oct. 2, 2011