Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: DNA-directed RNA polymerases I, II, and III subunit RPABC2


DESCRIPTION:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB6 is part of the clamp element and togther with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).

MISCELLANEOUS:
Present with 6090 molecules/cell in log phase SD medium.


STRUCTURE SIMILARITY:
Belongs to the archaeal rpoK/eukaryotic RPB6 RNA polymerase subunit family.


RELATED PATHWAY(S):
transcription


Amino acids sequence

        10         20         30         40         50         60
MSDYEEAFND GNENFEDFDV EHFSDEETYE EKPQFKDGET TDANGKTIVT GGNGPEDFQQ
        70         80         90        100        110        120
HEQIRRKTLK EKAIPKDQRA TTPYMTKYER ARILGTRALQ ISMNAPVFVD LEGETDPLRI
       130        140        150
AMKELAEKKI PLVIRRYLPD GSFEDWSVEE LIVDL  

Encoded by RPO26 gene


OTHER NAME(S):
RPB6


Nucleic acid sequence

        10         20         30         40         50         60
atgtcagact acgaggaggc gtttaacgac ggtaatgaga acttcgaaga ttttgatgta
        70         80         90        100        110        120
gagcattttt ctgatgagga gacttatgag gaaaaacctc aattcaagga tggtgaaaca
       130        140        150        160        170        180
accgatgcca acggtaagac catcgttact ggtggtaatg gcccagaaga ttttcaacag
       190        200        210        220        230        240
catgagcaaa taagaagaaa gacacttaag gaaaaggcca tcccaaaaga ccaaagagca
       250        260        270        280        290        300
actactccat acatgaccaa atatgaaagg gcaagaattt taggtacaag agccctacaa
       310        320        330        340        350        360
atttccatga atgcgccagt ttttgtagat ttagaaggtg aaactgatcc attgcgtatt
       370        380        390        400        410        420
gccatgaagg agttggctga aaagaaaatt cctttggtta ttagaagata tttaccagat
       430        440        450        460
ggttcctttg aggactggag tgtggaggaa ctcattgtgg atttgtga 

Last modification date: Oct. 2, 2011