Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: DNA-directed RNA polymerase II subunit RPB9


DESCRIPTION:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template. Involved in the regulation of transcription elongation. Involved in DNA repair of damage in the transcribed strand. Mediates a transcription-coupled repair (TCR) subpathway of nucleotide excision repair (NER).

MISCELLANEOUS:
Present with 2440 molecules/cell in log phase SD medium.


STRUCTURE SIMILARITY:
Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
Contains 1 TFIIS-type zinc finger.


RELATED PATHWAY(S):
transcription


Amino acids sequence

        10         20         30         40         50         60
MTTFRFCRDC NNMLYPREDK ENNRLLFECR TCSYVEEAGS PLVYRHELIT NIGETAGVVQ
        70         80         90        100        110        120
DIGSDPTLPR SDRECPKCHS RENVFFQSQQ RRKDTSMVLF FVCLSCSHIF TSDQKNKRTQ

FS     

Encoded by RPB9 gene


OTHER NAME(S):
SSU73


Nucleic acid sequence

        10         20         30         40         50         60
atgactacgt ttagattttg tcgtgactgc aacaatatgt tgtaccctcg tgaggataaa
        70         80         90        100        110        120
gaaaataacc ggttgttatt tgaatgcaga acatgctcgt atgtagaaga agcgggcagt
       130        140        150        160        170        180
ccattggtct acaggcatga attgattacc aacattggtg aaactgcggg agtggtgcaa
       190        200        210        220        230        240
gatattggtt ccgatcccac tcttccgaga tctgatagag aatgtcccaa atgtcactct
       250        260        270        280        290        300
cgggaaaatg tgttttttca atcacaacaa agaagaaagg atacttcgat ggttttattc
       310        320        330        340        350        360
tttgtgtgct tatcttgctc acacatattt acttcagatc aaaaaaacaa aaggacgcag

ttttcatga     

Last modification date: Oct. 2, 2011