Escherichia coli Migula (bacterium) K-12 MG1655 [ECO]

FULL NAME: DNA-directed RNA polymerase subunit beta


DESCRIPTION:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

STRUCTURE SIMILARITY:
Belongs to the RNA polymerase beta chain family.


CATALYTIC ACTIVITY:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).


RELATED PATHWAY(S):
transcription


Amino acids sequence

        10         20         30         40         50         60
MVYSYTEKKR IRKDFGKRPQ VLDVPYLLSI QLDSFQKFIE QDPEGQYGLE AAFRSVFPIQ
        70         80         90        100        110        120
SYSGNSELQY VSYRLGEPVF DVQECQIRGV TYSAPLRVKL RLVIYEREAP EGTVKDIKEQ
       130        140        150        160        170        180
EVYMGEIPLM TDNGTFVING TERVIVSQLH RSPGVFFDSD KGKTHSSGKV LYNARIIPYR
       190        200        210        220        230        240
GSWLDFEFDP KDNLFVRIDR RRKLPATIIL RALNYTTEQI LDLFFEKVIF EIRDNKLQME
       250        260        270        280        290        300
LVPERLRGET ASFDIEANGK VYVEKGRRIT ARHIRQLEKD DVKLIEVPVE YIAGKVVAKD
       310        320        330        340        350        360
YIDESTGELI CAANMELSLD LLAKLSQSGH KRIETLFTND LDHGPYISET LRVDPTNDRL
       370        380        390        400        410        420
SALVEIYRMM RPGEPPTREA AESLFENLFF SEDRYDLSAV GRMKFNRSLL REEIEGSGIL
       430        440        450        460        470        480
SKDDIIDVMK KLIDIRNGKG EVDDIDHLGN RRIRSVGEMA ENQFRVGLVR VERAVKERLS
       490        500        510        520        530        540
LGDLDTLMPQ DMINAKPISA AVKEFFGSSQ LSQFMDQNNP LSEITHKRRI SALGPGGLTR
       550        560        570        580        590        600
ERAGFEVRDV HPTHYGRVCP IETPEGPNIG LINSLSVYAQ TNEYGFLETP YRKVTDGVVT
       610        620        630        640        650        660
DEIHYLSAIE EGNYVIAQAN SNLDEEGHFV EDLVTCRSKG ESSLFSRDQV DYMDVSTQQV
       670        680        690        700        710        720
VSVGASLIPF LEHDDANRAL MGANMQRQAV PTLRADKPLV GTGMERAVAV DSGVTAVAKR
       730        740        750        760        770        780
GGVVQYVDAS RIVIKVNEDE MYPGEAGIDI YNLTKYTRSN QNTCINQMPC VSLGEPVERG
       790        800        810        820        830        840
DVLADGPSTD LGELALGQNM RVAFMPWNGY NFEDSILVSE RVVQEDRFTT IHIQELACVS
       850        860        870        880        890        900
RDTKLGPEEI TADIPNVGEA ALSKLDESGI VYIGAEVTGG DILVGKVTPK GETQLTPEEK
       910        920        930        940        950        960
LLRAIFGEKA SDVKDSSLRV PNGVSGTVID VQVFTRDGVE KDKRALEIEE MQLKQAKKDL
       970        980        990       1000       1010       1020
SEELQILEAG LFSRIRAVLV AGGVEAEKLD KLPRDRWLEL GLTDEEKQNQ LEQLAEQYDE
      1030       1040       1050       1060       1070       1080
LKHEFEKKLE AKRRKITQGD DLAPGVLKIV KVYLAVKRRI QPGDKMAGRH GNKGVISKIN
      1090       1100       1110       1120       1130       1140
PIEDMPYDEN GTPVDIVLNP LGVPSRMNIG QILETHLGMA AKGIGDKINA MLKQQQEVAK
      1150       1160       1170       1180       1190       1200
LREFIQRAYD LGADVRQKVD LSTFSDEEVM RLAENLRKGM PIATPVFDGA KEAEIKELLK
      1210       1220       1230       1240       1250       1260
LGDLPTSGQI RLYDGRTGEQ FERPVTVGYM YMLKLNHLVD DKMHARSTGS YSLVTQQPLG
      1270       1280       1290       1300       1310       1320
GKAQFGGQRF GEMEVWALEA YGAAYTLQEM LTVKSDDVNG RTKMYKNIVD GNHQMEPGMP
      1330       1340
ESFNVLLKEI RSLGINIELE DE   

Encoded by rpoB gene


OTHER NAME(S):
ECK3978
ftsR
groN
JW3950
mbrD?
nitB
rif
ron
sdgB
stl
stv
tabD
tabG


DESCRIPTION:
HT_Cmplx11_Mem: [More information is available at EcoGene: EG10894]. Along with its ' partner, the subunit of is integrally involved in the enzymatic function of RNA polymerase. [More information is available at EcoCyc: EG10894].


Nucleic acid sequence

        10         20         30         40         50         60
atggtttact cctataccga gaaaaaacgt attcgtaagg attttggtaa acgtccacaa
        70         80         90        100        110        120
gttctggatg taccttatct cctttctatc cagcttgact cgtttcagaa atttatcgag
       130        140        150        160        170        180
caagatcctg aagggcagta tggtctggaa gctgctttcc gttccgtatt cccgattcag
       190        200        210        220        230        240
agctacagcg gtaattccga gctgcaatac gtcagctacc gccttggcga accggtgttt
       250        260        270        280        290        300
gacgtccagg aatgtcaaat ccgtggcgtg acctattccg caccgctgcg cgttaaactg
       310        320        330        340        350        360
cgtctggtga tctatgagcg cgaagcgccg gaaggcaccg taaaagacat taaagaacaa
       370        380        390        400        410        420
gaagtctaca tgggcgaaat tccgctcatg acagacaacg gtacctttgt tatcaacggt
       430        440        450        460        470        480
actgagcgtg ttatcgtttc ccagctgcac cgtagtccgg gcgtcttctt tgactccgac
       490        500        510        520        530        540
aaaggtaaaa cccactcttc gggtaaagtg ctgtataacg cgcgtatcat cccttaccgt
       550        560        570        580        590        600
ggttcctggc tggacttcga attcgatccg aaggacaacc tgttcgtacg tatcgaccgt
       610        620        630        640        650        660
cgccgtaaac tgcctgcgac catcattctg cgcgccctga actacaccac agagcagatc
       670        680        690        700        710        720
ctcgacctgt tctttgaaaa agttatcttt gaaatccgtg ataacaagct gcagatggaa
       730        740        750        760        770        780
ctggtgccgg aacgcctgcg tggtgaaacc gcatcttttg acatcgaagc taacggtaaa
       790        800        810        820        830        840
gtgtacgtag aaaaaggccg ccgtatcact gcgcgccaca ttcgccagct ggaaaaagac
       850        860        870        880        890        900
gacgtcaaac tgatcgaagt cccggttgag tacatcgcag gtaaagtggt tgctaaagac
       910        920        930        940        950        960
tatattgatg agtctaccgg cgagctgatc tgcgcagcga acatggagct gagcctggat
       970        980        990       1000       1010       1020
ctgctggcta agctgagcca gtctggtcac aagcgtatcg aaacgctgtt caccaacgat
      1030       1040       1050       1060       1070       1080
ctggatcacg gcccatatat ctctgaaacc ttacgtgtcg acccaactaa cgaccgtctg
      1090       1100       1110       1120       1130       1140
agcgcactgg tagaaatcta ccgcatgatg cgccctggcg agccgccgac tcgtgaagca
      1150       1160       1170       1180       1190       1200
gctgaaagcc tgttcgagaa cctgttcttc tccgaagacc gttatgactt gtctgcggtt
      1210       1220       1230       1240       1250       1260
ggtcgtatga agttcaaccg ttctctgctg cgcgaagaaa tcgaaggttc cggtatcctg
      1270       1280       1290       1300       1310       1320
agcaaagacg acatcattga tgttatgaaa aagctcatcg atatccgtaa cggtaaaggc
      1330       1340       1350       1360       1370       1380
gaagtcgatg atatcgacca cctcggcaac cgtcgtatcc gttccgttgg cgaaatggcg
      1390       1400       1410       1420       1430       1440
gaaaaccagt tccgcgttgg cctggtacgt gtagagcgtg cggtgaaaga gcgtctgtct
      1450       1460       1470       1480       1490       1500
ctgggcgatc tggataccct gatgccacag gatatgatca acgccaagcc gatttccgca
      1510       1520       1530       1540       1550       1560
gcagtgaaag agttcttcgg ttccagccag ctgtctcagt ttatggacca gaacaacccg
      1570       1580       1590       1600       1610       1620
ctgtctgaga ttacgcacaa acgtcgtatc tccgcactcg gcccaggcgg tctgacccgt
      1630       1640       1650       1660       1670       1680
gaacgtgcag gcttcgaagt tcgagacgta cacccgactc actacggtcg cgtatgtcca
      1690       1700       1710       1720       1730       1740
atcgaaaccc ctgaaggtcc gaacatcggt ctgatcaact ctctgtccgt gtacgcacag
      1750       1760       1770       1780       1790       1800
actaacgaat acggcttcct tgagactccg tatcgtaaag tgaccgacgg tgttgtaact
      1810       1820       1830       1840       1850       1860
gacgaaattc actacctgtc tgctatcgaa gaaggcaact acgttatcgc ccaggcgaac
      1870       1880       1890       1900       1910       1920
tccaacttgg atgaagaagg ccacttcgta gaagacctgg taacttgccg tagcaaaggc
      1930       1940       1950       1960       1970       1980
gaatccagct tgttcagccg cgaccaggtt gactacatgg acgtatccac ccagcaggtg
      1990       2000       2010       2020       2030       2040
gtatccgtcg gtgcgtccct gatcccgttc ctggaacacg atgacgccaa ccgtgcattg
      2050       2060       2070       2080       2090       2100
atgggtgcga acatgcaacg tcaggccgtt ccgactctgc gcgctgataa gccgctggtt
      2110       2120       2130       2140       2150       2160
ggtactggta tggaacgtgc tgttgccgtt gactccggtg taactgcggt agctaaacgt
      2170       2180       2190       2200       2210       2220
ggtggtgtcg ttcagtacgt ggatgcttcc cgtatcgtta tcaaagttaa cgaagacgag
      2230       2240       2250       2260       2270       2280
atgtatccgg gtgaagcagg tatcgacatc tacaacctga ccaaatacac ccgttctaac
      2290       2300       2310       2320       2330       2340
cagaacacct gtatcaacca gatgccgtgt gtgtctctgg gtgaaccggt tgaacgtggc
      2350       2360       2370       2380       2390       2400
gacgtgctgg cagacggtcc gtccaccgac ctcggtgaac tggcgcttgg tcagaacatg
      2410       2420       2430       2440       2450       2460
cgcgtagcgt tcatgccgtg gaatggttac aacttcgaag actccatcct cgtatccgag
      2470       2480       2490       2500       2510       2520
cgtgttgttc aggaagaccg tttcaccacc atccacattc aggaactggc gtgtgtgtcc
      2530       2540       2550       2560       2570       2580
cgtgacacca agctgggtcc ggaagagatc accgctgaca tcccgaacgt gggtgaagct
      2590       2600       2610       2620       2630       2640
gcgctctcca aactggatga atccggtatc gtttacattg gtgcggaagt gaccggtggc
      2650       2660       2670       2680       2690       2700
gacattctgg ttggtaaggt aacgccgaaa ggtgaaactc agctgacccc agaagaaaaa
      2710       2720       2730       2740       2750       2760
ctgctgcgtg cgatcttcgg tgagaaagcc tctgacgtta aagactcttc tctgcgcgta
      2770       2780       2790       2800       2810       2820
ccaaacggtg tatccggtac ggttatcgac gttcaggtct ttactcgcga tggcgtagaa
      2830       2840       2850       2860       2870       2880
aaagacaaac gtgcgctgga aatcgaagaa atgcagctca aacaggcgaa gaaagacctg
      2890       2900       2910       2920       2930       2940
tctgaagaac tgcagatcct cgaagcgggt ctgttcagcc gtatccgtgc tgtgctggta
      2950       2960       2970       2980       2990       3000
gccggtggcg ttgaagctga gaagctcgac aaactgccgc gcgatcgctg gctggagctg
      3010       3020       3030       3040       3050       3060
ggcctgacag acgaagagaa acaaaatcag ctggaacagc tggctgagca gtatgacgaa
      3070       3080       3090       3100       3110       3120
ctgaaacacg agttcgagaa gaaactcgaa gcgaaacgcc gcaaaatcac ccagggcgac
      3130       3140       3150       3160       3170       3180
gatctggcac cgggcgtgct gaagattgtt aaggtatatc tggcggttaa acgccgtatc
      3190       3200       3210       3220       3230       3240
cagcctggtg acaagatggc aggtcgtcac ggtaacaagg gtgtaatttc taagatcaac
      3250       3260       3270       3280       3290       3300
ccgatcgaag atatgcctta cgatgaaaac ggtacgccgg tagacatcgt actgaacccg
      3310       3320       3330       3340       3350       3360
ctgggcgtac cgtctcgtat gaacatcggt cagatcctcg aaacccacct gggtatggct
      3370       3380       3390       3400       3410       3420
gcgaaaggta tcggcgacaa gatcaacgcc atgctgaaac agcagcaaga agtcgcgaaa
      3430       3440       3450       3460       3470       3480
ctgcgcgaat tcatccagcg tgcgtacgat ctgggcgctg acgttcgtca gaaagttgac
      3490       3500       3510       3520       3530       3540
ctgagtacct tcagcgatga agaagttatg cgtctggctg aaaacctgcg caaaggtatg
      3550       3560       3570       3580       3590       3600
ccaatcgcaa cgccggtgtt cgacggtgcg aaagaagcag aaattaaaga gctgctgaaa
      3610       3620       3630       3640       3650       3660
cttggcgacc tgccgacttc cggtcagatc cgcctgtacg atggtcgcac tggtgaacag
      3670       3680       3690       3700       3710       3720
ttcgagcgtc cggtaaccgt tggttacatg tacatgctga aactgaacca cctggtcgac
      3730       3740       3750       3760       3770       3780
gacaagatgc acgcgcgttc caccggttct tacagcctgg ttactcagca gccgctgggt
      3790       3800       3810       3820       3830       3840
ggtaaggcac agttcggtgg tcagcgtttc ggggagatgg aagtgtgggc gctggaagca
      3850       3860       3870       3880       3890       3900
tacggcgcag catacaccct gcaggaaatg ctcaccgtta agtctgatga cgtgaacggt
      3910       3920       3930       3940       3950       3960
cgtaccaaga tgtataaaaa catcgtggac ggcaaccatc agatggagcc gggcatgcca
      3970       3980       3990       4000       4010       4020
gaatccttca acgtattgtt gaaagagatt cgttcgctgg gtatcaacat cgaactggaa

gacgagtaa     

Last modification date: Oct. 2, 2011