Amino acids sequence

        10         20         30         40         50         60
MFSEQAAQRA HTLLSPPSAN NATFARVPVA TYTNSSQPFR LGERSFSRQY AHIYATRLIQ
        70         80         90        100        110        120
MRPFLENRAQ QHWGSGVGVK KLCELQPEEK CCVVGTLFKA MPLQPSILRE VSEEHNLLPQ
       130        140        150        160        170        180
PPRSKYIHPD DELVLEDELQ RIKLKGTIDV SKLVTGTVLA VFGSVRDDGK FLVEDYCFAD
       190        200        210        220        230        240
LAPQKPAPPL DTDRFVLLVS GLGLGGGGGE SLLGTQLLVD VVTGQLGDEG EQCSAAHVSR
       250        260        270        280        290        300
VILAGNLLSH STQSRDSINK AKYLTKKTQA ASVEAVKMLD EILLQLSASV PVDVMPGEFD
       310        320        330        340        350        360
PTNYTLPQQP LHPCMFPLAT AYSTLQLVTN PYQATIDGVR FLGTSGQNVS DIFRYSSMED
       370        380        390        400        410        420
HLEILEWTLR VRHISPTAPD TLGCYPFYKT DPFIFPECPH VYFCGNTPSF GSKIIRGPED
       430        440        450        460
QTVLLVTVPD FSATQTACLV NLRSLACQPI SFSGFGAEDD DLGGLGLGP 

Encoded by POLD2 gene

FULL NAME: polymerase (DNA directed), delta 2, regulatory subunit 50kDa


DESCRIPTION:
The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA; MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2, POLD3 (MIM 611415), and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied by OMIM, Mar 2008]


Nucleic acid sequence

        10         20         30         40         50         60
atgttttctg agcaggctgc ccagagggcc cacactctac tgtccccacc atcagccaac
        70         80         90        100        110        120
aatgccacct ttgcccgggt gccagtggca acctacacca actcctcaca acccttccgg
       130        140        150        160        170        180
ctaggagagc gcagctttag ccggcagtat gcccacattt atgccacccg cctcatccaa
       190        200        210        220        230        240
atgagaccct tcctggagaa ccgggcccag cagcactggg gcagtggagt gggagtgaag
       250        260        270        280        290        300
aagctgtgtg aactgcagcc tgaggagaag tgctgtgtgg tgggcactct gttcaaggcc
       310        320        330        340        350        360
atgccgctgc agccctccat cctgcgggag gtcagcgagg agcacaacct gctcccccag
       370        380        390        400        410        420
cctcctcgga gtaaatacat acacccagat gacgagctgg tcttggaaga tgaactgcag
       430        440        450        460        470        480
cgtatcaaac taaaaggcac cattgacgtg tcaaagctgg ttacggggac tgtcctggct
       490        500        510        520        530        540
gtgtttggct ccgtgagaga cgacgggaag tttctggtgg aggactattg ctttgctgac
       550        560        570        580        590        600
cttgctcccc agaagcccgc acccccactt gacacagata ggtttgtgct actggtgtcc
       610        620        630        640        650        660
ggcctgggcc tgggtggcgg tggaggcgag agcctgctgg gcacccagct gctggtggat
       670        680        690        700        710        720
gtggtgacgg ggcagcttgg ggacgaaggg gagcagtgca gcgccgccca cgtctcccgg
       730        740        750        760        770        780
gttatcctcg ctggcaacct cctcagccac agcacccaga gcagggattc tatcaataag
       790        800        810        820        830        840
gccaaatacc tcaccaagaa aacccaggca gccagcgtgg aggctgttaa gatgctggat
       850        860        870        880        890        900
gagatcctcc tgcagctgag cgcctcagtg cccgtggacg tgatgccagg cgagtttgat
       910        920        930        940        950        960
cccaccaatt acacgctccc ccagcagccc ctccacccct gcatgttccc gctggccact
       970        980        990       1000       1010       1020
gcctactcca cgctccagct ggtcaccaac ccctaccagg ccaccattga tggagtcaga
      1030       1040       1050       1060       1070       1080
tttttgggga catcaggaca gaacgtgagt gacattttcc gatacagcag catggaggat
      1090       1100       1110       1120       1130       1140
cacttggaga tcctggagtg gaccctgcgg gtccgtcaca tcagccccac agcccctgac
      1150       1160       1170       1180       1190       1200
actctaggtt gttacccctt ctacaaaact gacccgttca tcttcccaga gtgcccgcat
      1210       1220       1230       1240       1250       1260
gtctactttt gtggcaacac ccccagcttt ggctccaaaa tcatccgagg tcctgaggac
      1270       1280       1290       1300       1310       1320
cagacagtgc tgttggtgac tgtccctgac ttcagtgcca cgcagaccgc ctgccttgtg
      1330       1340       1350       1360       1370       1380
aacctgcgca gcctggcctg ccagcccatc agcttctcgg gcttcggggc agaggacgat
      1390       1400       1410
gacctgggag gcctggggct gggcccctga   

Last modification date: Oct. 2, 2011