Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: DNA primase small subunit


DESCRIPTION:
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

MISCELLANEOUS:
The bound zinc ion is not a cofactor. It is bound to a zinc knuckle motif that may be involved in sequence recognition and the binding of ssDNA (By similarity).


STRUCTURE SIMILARITY:
Belongs to the eukaryotic-type primase small subunit family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MTVQIDELDD KDLDEIIANG TLDGAKQGAV DSETMIQYYR HLFPWKYLFQ WLNHGPVVTN
        70         80         90        100        110        120
DFAHREFAFT LPNDAYIRYL SFSNWEELKK EALNLCPSRF EVGPVYSANP RDRKTIRKST
       130        140        150        160        170        180
FHPLKKELVF DIDMTDYDDV RTCCSKTNIC EKCWPFITIA VQVLDICFHE DFGFKHILWV
       190        200        210        220        230        240
YSGRRGIHAW ICDEIACSLD DRSRRMIASY LQVVVGNPQG GVRLINNLKR PLHPHLTRSL
       250        260        270        280        290        300
NILKSAFVKI VLEDQDPWAS KEGAENLLKL LPDKDLASAL RKKWEVDPER SSKNKWSDID
       310        320        330        340        350        360
TVLASGSIAS ISPSVIAIAK QDIVLTYLYP RLDVEVSRHL NHLLKSPFCV HPGTSRVCVP
       370        380        390        400        410        420
IDIERMDSFN PLKVPTVNDL LQELDKNSQN DNGHGPTMET NTTENQKDNA RGQSNKGHGF
       430        440        450
STSLNPYTLY FKSFSSQLFK ETVGNKRKHE NLEF  

Encoded by spp1 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgactgttc aaatcgatga attggacgac aaagatttgg atgagataat tgcaaacgga
        70         80         90        100        110        120
acacttgatg gcgctaaaca gggagctgtg gattcagaga cgatgattca atattatcgc
       130        140        150        160        170        180
catctttttc cgtggaaata tttatttcaa tggttaaatc atggtccggt agtcactaat
       190        200        210        220        230        240
gattttgctc atcgggagtt cgcgttcaca cttcctaatg atgcttatat tcgttattta
       250        260        270        280        290        300
tctttttcaa attgggaaga gttaaaaaag gaagctttaa atttatgccc aagccgattt
       310        320        330        340        350        360
gaagttggac ccgtttatag tgccaatccc agggacagga aaacaataag gaagtcaaca
       370        380        390        400        410        420
tttcatccgc ttaaaaagga actcgttttt gatatagata tgactgacta cgatgatgta
       430        440        450        460        470        480
cgaacctgct gctcaaaaac aaatatatgc gaaaaatgct ggccatttat tacgatcgca
       490        500        510        520        530        540
gttcaagttt tagatatttg ttttcatgag gactttggat ttaaacacat attgtgggta
       550        560        570        580        590        600
tactctggtc gaagaggtat tcacgcttgg atttgtgacg aaattgcttg ttctttagac
       610        620        630        640        650        660
gatcggtctc gtagaatgat tgccagttat ttacaggttg tagtaggtaa tcctcaaggt
       670        680        690        700        710        720
ggcgtacgac ttattaataa cttaaaaaga ccccttcacc cacatttgac tcgttctctc
       730        740        750        760        770        780
aacattctca aatcggcctt tgtaaaaatt gtccttgaag accaagatcc gtgggcttct
       790        800        810        820        830        840
aaagaaggag ccgaaaacct tttgaaatta ctaccagaca aggatttagc atctgctctt
       850        860        870        880        890        900
cgtaaaaaat gggaggttga tcctgaacga tctagcaaaa ataaatggtc cgacattgac
       910        920        930        940        950        960
actgtcttag catctggttc tattgcctct atatctcctt cagtaattgc gattgccaag
       970        980        990       1000       1010       1020
caggacattg ttttaaccta tttgtatcca agattggatg ttgaggtttc tagacattta
      1030       1040       1050       1060       1070       1080
aaccatttgc taaaatctcc attttgcgtc caccccggaa ctagtcgtgt ttgtgttccc
      1090       1100       1110       1120       1130       1140
atagatatag agaggatgga ttcttttaat cctttgaaag tacccactgt gaatgatctt
      1150       1160       1170       1180       1190       1200
ttgcaagagt tggataaaaa ttcccaaaat gataacggcc atggtccaac aatggaaact
      1210       1220       1230       1240       1250       1260
aatacaacag aaaaccaaaa agataatgct aggggacaat caaacaaggg gcatggcttt
      1270       1280       1290       1300       1310       1320
tcaacttctc tcaatcctta tacgctgtac tttaaatcgt tcagtagcca gctttttaaa
      1330       1340       1350       1360
gaaacagtag gaaataaaag aaaacatgag aatttggaat tttaa 

Last modification date: Oct. 2, 2011