Homo sapiens L. (human) [HSA]

FULL NAME: DNA-directed RNA polymerases I, II, and III subunit RPABC3


DESCRIPTION:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

STRUCTURE SIMILARITY:
Belongs to the eukaryotic RPB8 RNA polymerase subunit family.


RELATED PATHWAY(S):
transcription


Amino acids sequence

        10         20         30         40         50         60
MAGILFEDIF DVKDIDPEGK KFDRVSRLHC ESESFKMDLI LDVNIQIYPV DLGDKFRLVI
        70         80         90        100        110        120
ASTLYEDGTL DDGEYNPTDD RPSRADQFEY VMYGKVYRIE GDETSTEAAT RLSAYVSYGG
       130        140        150
LLMRLQGDAN NLHGFEVDSR VYLLMKKLAF   

Encoded by POLR2H gene

FULL NAME: polymerase (RNA) II (DNA directed) polypeptide H


OTHER NAME(S):
RPABC3
RPB17
RPB8
hsRPB8


DESCRIPTION:
This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. [provided by RefSeq, Jul 2008]


Nucleic acid sequence

        10         20         30         40         50         60
atggcgggca tcctgtttga ggatattttc gatgtgaagg atattgaccc ggagggcaag
        70         80         90        100        110        120
aagtttgacc gagtgtctcg actgcattgt gagagtgaat ctttcaagat ggatctaatc
       130        140        150        160        170        180
ttagatgtaa acattcaaat ttaccctgta gacttgggtg acaagttccg gttggtcata
       190        200        210        220        230        240
gctagtacct tgtatgaaga tggtaccctg gatgatggtg aatacaaccc cactgatgat
       250        260        270        280        290        300
aggccttcca gggctgacca gtttgagtat gtaatgtatg gaaaagtgta caggattgag
       310        320        330        340        350        360
ggagatgaaa cttctactga agcagcaaca cgcctctctg cgtacgtgtc ctatgggggc
       370        380        390        400        410        420
ctgctcatga ggctgcaggg ggatgccaac aacctgcatg gattcgaggt ggactccaga
       430        440        450
gtttatctcc tgatgaagaa gctagccttc tga  

Last modification date: Oct. 2, 2011