Caenorhabditis elegans Maupas (nematode) [CEL]

FULL NAME: DNA topoisomerase III (hypothetical protein)


MISCELLANEOUS:
Evidence at transcript level.


STRUCTURE SIMILARITY:
Belongs to the prokaryotic type I/III topoisomerase family.


CATALYTIC ACTIVITY:
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.


PROTEIN TYPE(S):
DNA topoisomerase


RELATED PATHWAY(S):
DNA replication
homologous recombination (HR)
Fanconi anemia (FA) pathway


Amino acids sequence

        10         20         30         40         50         60
MAPTVLMVAE KPLLADSIAN LLSNGQAKKR KGWNGVCSVS EYDGQFNGRA ARFKVTSTCG
        70         80         90        100        110        120
HVMSLDFPPK FNNWERVDPA ELYSAPTQRI EANPKMKMNE FLASEAKNAD FLVLWLDCDK
       130        140        150        160        170        180
EGENICFEVI DAVKCAMFKN RQDFMSDVYR AHFSAITEKD IKAAMRNLGR PDQNMSHSVD
       190        200        210        220        230        240
ARQELDLRIG CSFTRFQTKF FQGKYGDLDS NVISYGPCQT PTLGFCVTRH DQIVQFKPEQ
       250        260        270        280        290        300
YWVLKTNFTT SDDGQIFSPE WQRGRIFDAE VARVFVDRIK KCHTGLVLDV SKKEARKERP
       310        320        330        340        350        360
CALNTVELMR VASSSLGMSP STTMHVAEAL YTQGYISYPR TETTAYSANF DLTGTLKILA
       370        380        390        400        410        420
GDRKWGSVVL ADGIKRPKSG VDKGDHPPIT PMRPNHGGLS GDMSRIYEYV SQHFVATLMK
       430        440        450        460        470        480
QCVYEVTTVK MSCGDEQFTL QGKNVVEPGF TAVMPWLSVE EECSVPKSLQ QIGAKIELQN
       490        500        510        520        530        540
AEIQARETTP PGYLTEAELI TLMEKHGIGT DASIPVHINT ITQRNYVTVE SGRRLVPTRL
       550        560        570        580        590        600
GQCLVRGYWK VDPELVLPTM RAELEEQLNL VASGKADYLD RNFEKKFLIE NFIFFKTFFV
       610        620        630        640        650        660
EKNENTGKPF SRCGKCRRYM KLVQTKPQRL YCPTCQETYA VPNFKDGVLK VIGDHKCPLD
       670        680        690        700        710        720
DFDVILYQGP GGKLARTFTL CPFCFNNPPF EKMPQGAGCD TCVHPSCQYS ISSNGVCGCL
       730        740        750        760        770        780
QDCGGVMLLD TQSHPKWRMT CNKCPSVVGL FEGAIKVKVD STRSCEQCDA QFIKAEFKPN
       790        800        810        820        830        840
SGKPGAIEYE SSSYEGCIFC DAMKKYPDAI NLNHAYLTEE SRQRNTQAPR RGGGGGRGRG
       850
GRGRGGRGRG RGRGR    

Encoded by Y48C3A.14 gene

FULL NAME: DNA topoisomerase III


Last modification date: Oct. 14, 2011