Caenorhabditis elegans Maupas (nematode) [CEL]


STRUCTURE SIMILARITY:
Belongs to the DNA mismatch repair mutS family.


RELATED PATHWAY(S):
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MSKRQSSLMS FFTKTPKSEK PEEEVKEKSV EEPKSLKNDT PKISNDSEKK VLKRSNSKTV
        70         80         90        100        110        120
SSPVKTPRNA SKRPKVVVCS SSEGEDDDGD EDFEMKEAEE HESSDESEAD ENASDCEVVE
       130        140        150        160        170        180
SPESTPQSTP KRGGKKKISK PLLAENTPKS VKMAGKSKKV IPDGEAVSMA GVLDKMDKIM
       190        200        210        220        230        240
DGEGERKRIV EKTTGAKNKA VELEPAERFD HESFDFLKPD KIRDGFKRPM SDPEYDPKTL
       250        260        270        280        290        300
WVPPDFHQKQ TPGHRQWWTM KSQHFDTILL FKVGKFYETY HMDAVEVVRA LNIAFMRGSY
       310        320        330        340        350        360
AHAGFPEHAA SKFADQLMNH GYKVARIEQT ETPQMLEERN QKTKTKEKVV RREVCRVTSN
       370        380        390        400        410        420
GTRTYGVLDG VDLGSASSTL DPTAKHLLAI KEFHNPETGK SSYGVCMIDT TTAHIRIGQF
       430        440        450        460        470        480
EDDDYRSQLR TLLANVIVVQ AIVERGSISS TTKSIINGIL FSVPVEHLLP KKQFMTAEDV
       490        500        510        520        530        540
VRIVSNEDYY GSDASEWPEV LKGMLEDSSI LPKPSTDWQL ALSAFGAIFW YLRDSLIDVD
       550        560        570        580        590        600
MLSMRNVTIY NSNSMENDQK KEKIDWNGKN LILDGTALEN LNIVPNGRDS HLTSLYYVIN
       610        620        630        640        650        660
KCSTPFGRRL LRSWLLQPTC DPKKLEQRQK AIKWLVSPDA SSFMTTATAT LKKIPDLDRL
       670        680        690        700        710        720
LQKIHTIGLK YRSEKHPDSR AIFFDTIKTN QKKIAELLAA IDGFKLCNKL RKEYIKVQKE
       730        740        750        760        770        780
GEGCELLDEL LGNEQEMEEV DENIYFFEKM FDRSTAMKDG KIVPNAGCDE EYDEALNRVK
       790        800        810        820        830        840
EALNELNDYK DSVAKKYSCS IKFVDSGKVK YLLEMPENTK VSSSFELKSR RKGFIRYSTP
       850        860        870        880        890        900
DSEQLVAALD AVEKEKSKLG DDATRRVFEQ FGHKNPIWLE TVKLVSSFDV LTSLALFAKS
       910        920        930        940        950        960
SPFEMCMPEF DFNATDPYLI VDKGVHPCLA LQSRNEVTQT TSFIANSTTM GASEAAVMLL
       970        980        990       1000       1010       1020
TGPNMGGKST LMRQTAVLAI LAHIGSMVPA FSMRLTPIDR IFTRIGANDR IMCGESTFFI
      1030       1040       1050       1060       1070       1080
ELKETDIMLK NATKHSLLLV DELGRGTSTF DGTAIASAVL QKISDDLACR TFFSTHYHSI
      1090       1100       1110       1120       1130       1140
CDSFTNHPNV RLAHMKCVVD KENNEDPTME DVTFLYELES GICPKSYGFY AAKLAGIDHQ
      1150       1160       1170       1180
VVRNAYLESN KFASNLIIDP KIRHLVECAR DDNFDVGELK RMIEAI 

Encoded by msh-6 gene

FULL NAME: MSH (MutS Homolog) family


Nucleic acid sequence

        10         20         30         40         50         60
atgtcgaagc gacaaagctc actgatgtct ttcttcacca aaactccgaa atctgagaag
        70         80         90        100        110        120
ccggaggaag aagttaaaga aaaaagtgtt gaggagccga aatcactgaa aaatgatact
       130        140        150        160        170        180
ccgaagatat caaatgattc cgaaaagaag gtcttgaaac gatccaactc aaaaaccgtc
       190        200        210        220        230        240
agctcaccgg taaaaactcc aagaaacgcg tcaaaacgtc caaaagtcgt cgtttgttcc
       250        260        270        280        290        300
tcttctgaag gtgaagatga cgatggagat gaggattttg agatgaaaga agccgaagaa
       310        320        330        340        350        360
cacgaatcat cggatgaatc ggaagctgat gagaatgcga gtgactgtga agttgttgaa
       370        380        390        400        410        420
tcgccagaga gcacaccgca gagcacaccg aaacgaggag gaaagaagaa gatttcgaaa
       430        440        450        460        470        480
cctctcctcg ctgaaaacac cccaaaaagc gtaaaaatgg ctggaaaatc gaaaaaagtg
       490        500        510        520        530        540
attcccgacg gagaagccgt gtcgatggcc ggagttttgg acaaaatgga taaaattatg
       550        560        570        580        590        600
gacggagagg gtgaacgcaa gcgaatcgtc gagaaaacca ccggagccaa gaacaaggca
       610        620        630        640        650        660
gtggagctgg agcccgctga aagatttgat catgaatctt ttgattttct gaagccggat
       670        680        690        700        710        720
aaaattcgtg atggtttcaa gcgtccgatg tctgatccag aatatgatcc aaaaactctc
       730        740        750        760        770        780
tgggttcctc cagattttca tcaaaaacag acaccaggtc atcgacaatg gtggactatg
       790        800        810        820        830        840
aaatcacagc atttcgatac aattctcctt tttaaagttg gaaaattcta tgaaacatat
       850        860        870        880        890        900
catatggatg cagtggaagt tgttcgtgca cttaatattg cttttatgcg tggatcatat
       910        920        930        940        950        960
gctcatgctg gcttcccgga gcacgcagcc tcaaaattcg ctgatcaact aatgaatcac
       970        980        990       1000       1010       1020
ggctataaag tggctcggat cgagcagact gagacacctc aaatgttgga ggagagaaat
      1030       1040       1050       1060       1070       1080
cagaaaacga aaacaaagga aaaagttgtg aggagagaag tgtgtagggt tacatcgaat
      1090       1100       1110       1120       1130       1140
ggaacacgaa cttatggagt tttggatggt gttgatttgg gaagtgcttc gtcgacgttg
      1150       1160       1170       1180       1190       1200
gatccgactg ctaagcattt gttggcgatt aaggaattcc ataacccaga aacaggaaaa
      1210       1220       1230       1240       1250       1260
tcctcctacg gagtgtgcat gattgacaca acgactgcac acattcgtat cggacaattt
      1270       1280       1290       1300       1310       1320
gaagatgatg actatcgttc acaactgcgt acacttctcg cgaatgtgat tgttgttcag
      1330       1340       1350       1360       1370       1380
gcgatcgttg agcgtggatc catctcttca accactaaat caattattaa tggaattctt
      1390       1400       1410       1420       1430       1440
ttctcggttc ccgttgagca tttactcccg aaaaagcaat ttatgacagc cgaagatgtt
      1450       1460       1470       1480       1490       1500
gtgagaattg tttcaaatga agattattat ggatctgatg cttctgaatg gccggaagtt
      1510       1520       1530       1540       1550       1560
ctgaagggaa tgctggagga ttccagtatt cttccaaaac cttcaaccga ctggcaactg
      1570       1580       1590       1600       1610       1620
gctctttcag catttggagc aattttctgg tatcttcgtg acagcctaat cgatgtggat
      1630       1640       1650       1660       1670       1680
atgttatcaa tgaggaatgt gactatttat aattcgaatt ctatggaaaa tgatcagaaa
      1690       1700       1710       1720       1730       1740
aaggaaaaga ttgactggaa cggaaagaat ctgattctcg acggaactgc actggaaaat
      1750       1760       1770       1780       1790       1800
ctgaatattg taccaaatgg cagagattct catctcactt ccctctacta tgtcattaac
      1810       1820       1830       1840       1850       1860
aaatgctcca caccatttgg ccgtcgactt ctccgttcgt ggcttcttca accgacttgt
      1870       1880       1890       1900       1910       1920
gatccgaaaa agctcgagca acgacagaaa gccattaagt ggctcgtttc accggatgcc
      1930       1940       1950       1960       1970       1980
tcgtcattta tgacgactgc gacggctacg ttgaaaaaga ttccagattt ggatagactt
      1990       2000       2010       2020       2030       2040
ttgcaaaaaa tccacacaat tggcctcaaa taccgttccg aaaagcatcc ggacagtcgt
      2050       2060       2070       2080       2090       2100
gcaatcttct tcgatacaat caaaacaaat cagaaaaaaa tcgccgaact tttggccgca
      2110       2120       2130       2140       2150       2160
attgatggat tcaaactgtg taataaactg agaaaagagt atataaaagt acaaaaagag
      2170       2180       2190       2200       2210       2220
ggtgaaggat gtgaattact tgatgaatta cttggaaatg agcaagaaat ggaagaagtc
      2230       2240       2250       2260       2270       2280
gatgagaata tctacttttt cgagaaaatg ttcgatcgaa gcacggctat gaaagatggg
      2290       2300       2310       2320       2330       2340
aaaattgtgc cgaatgcggg atgtgatgag gaatatgatg aagctttgaa tcgagtgaag
      2350       2360       2370       2380       2390       2400
gaagcattga atgaattgaa tgattataag gattctgttg ccaagaaata tagttgctcg
      2410       2420       2430       2440       2450       2460
atcaaattcg tggattcagg aaaagtaaag tacctactgg aaatgcctga aaacacgaaa
      2470       2480       2490       2500       2510       2520
gtctcatcgt cattcgagct gaaatctcgt cgaaagggct tcatccgata ctctacaccg
      2530       2540       2550       2560       2570       2580
gattctgagc aactggtcgc cgctcttgat gcagttgaaa aggaaaaatc aaaattgggt
      2590       2600       2610       2620       2630       2640
gatgatgcga ctcgtcgtgt attcgaacaa tttggacaca aaaatccaat ttggttggag
      2650       2660       2670       2680       2690       2700
actgtgaagc ttgtctcgag ctttgatgtg ctcacctcat tggctttgtt cgcaaaatct
      2710       2720       2730       2740       2750       2760
tctccattcg agatgtgtat gccggaattc gatttcaacg ccacggatcc ttatctgatc
      2770       2780       2790       2800       2810       2820
gttgacaagg gtgtacatcc atgtttggcg ttacaatcaa gaaatgaagt tacccagaca
      2830       2840       2850       2860       2870       2880
acatcgttca ttgcgaatag taccacaatg ggagcatctg aagctgctgt gatgcttctg
      2890       2900       2910       2920       2930       2940
actggtccga atatgggtgg aaaatctacg ttgatgaggc aaaccgctgt tctggcgatt
      2950       2960       2970       2980       2990       3000
ctcgctcata ttggttcaat ggttcctgcc ttctcgatgc ggctcactcc aatcgatcga
      3010       3020       3030       3040       3050       3060
attttcactc gtattggagc caacgatagg attatgtgcg gagaatcaac attcttcatt
      3070       3080       3090       3100       3110       3120
gagctaaaag aaactgatat tatgctcaaa aatgcgacaa agcattctct cttgctcgtc
      3130       3140       3150       3160       3170       3180
gacgagctcg gtcgtggcac aagtacattc gatggaactg ccattgcttc tgctgtttta
      3190       3200       3210       3220       3230       3240
caaaagattt ctgatgattt ggcgtgtcga acattctttt ctacacatta tcactcgatt
      3250       3260       3270       3280       3290       3300
tgtgactcat ttactaatca tccgaatgtc agattggccc atatgaaatg tgtcgtggat
      3310       3320       3330       3340       3350       3360
aaggagaaca atgaggatcc aacaatggaa gatgtcactt tcttatacga actcgaatct
      3370       3380       3390       3400       3410       3420
ggaatttgcc caaaatccta cggtttctat gcagcaaaac tggctggaat tgaccatcaa
      3430       3440       3450       3460       3470       3480
gtcgttcgaa atgcctattt ggaaagcaat aaattcgcat caaatctcat cattgatccc
      3490       3500       3510       3520       3530       3540
aaaatccgac atcttgttga atgtgctcgt gacgataatt ttgatgttgg agagttgaag
      3550       3560
cgaatgattg aagccatcta a   

Last modification date: Oct. 2, 2011