Escherichia coli Migula (bacterium) K-12 MG1655 [ECO]

FULL NAME: Single-stranded DNA-binding protein


DESCRIPTION:
This protein is essential for replication of the chromosomes and its single-stranded DNA phages. It is also involved in DNA recombination and repair.

STRUCTURE SIMILARITY:
Contains 1 SSB domain.


POST-TRANSLATIONAL MODIFICATION:
Phosphorylated on tyrosine residue(s).


PROTEIN TYPE(S):
accessory protein


RELATED PATHWAY(S):
DNA replication
mismatch repair (MMR)
homologous recombination (HR)
prokaryotic (SOS) response


Amino acids sequence

        10         20         30         40         50         60
MASRGVNKVI LVGNLGQDPE VRYMPNGGAV ANITLATSES WRDKATGEMK EQTEWHRVVL
        70         80         90        100        110        120
FGKLAEVASE YLRKGSQVYI EGQLRTRKWT DQSGQDRYTT EVVVNVGGTM QMLGGRQGGG
       130        140        150        160        170
APAGGNIGGG QPQGGWGQPQ QPQGGNQFSG GAQSRPQQSA PAAPSNEPPM DFDDDIPF

Encoded by ssb gene


OTHER NAME(S):
ECK4051
exrB
JW4020
lexC


DESCRIPTION:
SSB binds to RecQ and stimulates DNA unwinding (Shereda, 2007). [More information is available at EcoGene: EG10976]. The product of the essential ssb gene, the highly stable single-stranded DNA binding protein SSB, is involved in replication, recombination, and repair in the DNA metabolism of Escherichia coli. [More information is available at EcoCyc: EG10976].


Nucleic acid sequence

        10         20         30         40         50         60
atggccagca gaggcgtaaa caaggttatt ctcgttggta atctgggtca ggacccggaa
        70         80         90        100        110        120
gtacgctaca tgccaaatgg tggcgcagtt gccaacatta cgctggctac ttccgaatcc
       130        140        150        160        170        180
tggcgtgata aagcgaccgg cgagatgaaa gaacagactg aatggcaccg cgttgtgctg
       190        200        210        220        230        240
ttcggcaaac tggcagaagt ggcgagcgaa tatctgcgta aaggttctca ggtttatatc
       250        260        270        280        290        300
gaaggtcagc tgcgtacccg taaatggacc gatcaatccg gtcaggatcg ctacaccaca
       310        320        330        340        350        360
gaagtcgtgg tgaacgttgg cggcaccatg cagatgctgg gtggtcgtca gggtggtggc
       370        380        390        400        410        420
gctccggcag gtggcaatat cggtggtggt cagccgcagg gcggttgggg tcagcctcag
       430        440        450        460        470        480
cagccgcagg gtggcaatca gttcagcggc ggcgcgcagt ctcgcccgca gcagtccgct
       490        500        510        520        530
ccggcagcgc cgtctaacga gccgccgatg gactttgatg atgacattcc gttctga

Last modification date: Oct. 2, 2011