Escherichia coli Migula (bacterium) K-12 MG1655 [ECO]

FULL NAME: Exodeoxyribonuclease 10


DESCRIPTION:
Capable of degrading both single-strand and double-strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre-synaptic and/or post-synaptic DNA degradation.

RELATED PATHWAY(S):
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MLRIIDTETC GLQGGIVEIA SVDVIDGKIV NPMSHLVRPD RPISPQAMAI HRITEAMVAD
        70         80         90        100        110        120
KPWIEDVIPH YYGSEWYVAH NASFDRRVLP EMPGEWICTM KLARRLWPGI KYSNMALYKT
       130        140        150        160        170        180
RKLNVQTPPG LHHHRALYDC YITAALLIDI MNTSGWTAEQ MADITGRPSL MTTFTFGKYR
       190        200        210        220
GKAVSDVAER DPGYLRWLFN NLDSMSPELR LTLKHYLENT  

Encoded by exoX gene


OTHER NAME(S):
ECK1845
JW1833
yobC


DESCRIPTION:
Exonuclease X is a DNA repair enzyme involved in mismatch repair, and is able to degrade both single-stranded and duplex DNA . [More information is available at EcoCyc: G7016].


Nucleic acid sequence

        10         20         30         40         50         60
atgttgcgca ttatcgatac agaaacctgc ggtttgcagg gagggatcgt tgagattgcc
        70         80         90        100        110        120
tctgttgatg tcattgacgg aaaaatcgtc aaccccatga gccacctggt gcgccccgat
       130        140        150        160        170        180
cgtcctatta gtccacaagc gatggcgatt catcgcatca ccgaagccat ggtcgccgat
       190        200        210        220        230        240
aaaccgtgga ttgaagatgt gatcccacac tattacggta gtgaatggta tgtcgcgcat
       250        260        270        280        290        300
aacgccagct ttgaccgccg cgtactgcct gagatgcccg gtgagtggat ttgcactatg
       310        320        330        340        350        360
aaactggccc gtcgtttgtg gcctgggatc aagtacagca atatggcgtt atataaaaca
       370        380        390        400        410        420
cgcaagctca atgtacagac gccgccgggc ctgcatcatc accgcgcgtt gtatgactgt
       430        440        450        460        470        480
tatatcaccg ccgcgttgct tatcgatatt atgaacacct ccggctggac ggcagaacag
       490        500        510        520        530        540
atggccgata tcaccggacg tccgtcgttg atgacgacct tcacctttgg caaataccgt
       550        560        570        580        590        600
ggcaaagcgg tttccgacgt tgccgaacgc gatccgggct atctgcgctg gttatttaat
       610        620        630        640        650        660
aacctggaca gcatgagccc ggagctgcgt ttaacactga aacattatct ggaaaatact

tag     

Last modification date: Oct. 2, 2011