Escherichia coli Migula (bacterium) K-12 MG1655 [ECO]

FULL NAME: Exodeoxyribonuclease 7 small subunit


DESCRIPTION:
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. It can also degrade 3' or 5' ss regions extending from the termini of duplex DNA molecules and displaced ss regions.

STRUCTURE SIMILARITY:
Belongs to the xseB family.


CATALYTIC ACTIVITY:
Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.


RELATED PATHWAY(S):
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MPKKNEAPAS FEKALSELEQ IVTRLESGDL PLEEALNEFE RGVQLARQGQ AKLQQAEQRV
        70         80
QILLSDNEDA SLTPFTPDNE    

Encoded by xseB gene


OTHER NAME(S):
ECK0416
JW0412
yajE


DESCRIPTION:
XseB is the small subunit of Exonuclease VII . [More information is available at EcoCyc: EG11098].


Nucleic acid sequence

        10         20         30         40         50         60
atgccgaaga aaaatgaggc gcccgccagc tttgaaaagg cgctgagcga gctggaacag
        70         80         90        100        110        120
attgtaaccc gtctggaaag tggcgacctg ccgctggaag aggcgctgaa cgagttcgaa
       130        140        150        160        170        180
cgcggcgtgc agctggcacg tcaggggcag gccaaattac aacaagccga acagcgcgta
       190        200        210        220        230        240
caaattctgc tgtctgacaa tgaagacgcc tctctaaccc cttttacacc ggacaatgag

taa     

Last modification date: Oct. 2, 2011