Drosophila melanogaster Meigen (fruit fly) [DME]

FULL NAME: DNA repair protein complementing XP-A cells homolog


DESCRIPTION:
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region (By similarity).

STRUCTURE SIMILARITY:
Belongs to the XPA family.


RELATED PATHWAY(S):
nucleotide excision repair (NER)


Amino acids sequence

        10         20         30         40         50         60
MSAEVSTNES APPAEKKSKL TNAQKARIER NQAKAQKLRE AKLVSHPFKE LASNKEGGTH
        70         80         90        100        110        120
PEAALSQGSS VIKVQGTKYI DSGGGFLLEQ PVMPTGVGPA GLNKSGEEAP PILDDAIAIP
       130        140        150        160        170        180
VQYEECLECG DMFADSYLFN NFGHSVCDKC RDKDERYALI TRTEAKAEYL LKDCDFDKRE
       190        200        210        220        230        240
PKLRYISRKN PHNVRWGEMK LYLHLQIHQR ALEVWGSEEE LVRQHEARED KREEGKARKY
       250        260        270        280        290
NKKMKQLRME VRSSIYTKKT HEVHEHEFGP DTYDEEEDTY THTCITCPYS ETYEKM

Encoded by Xpac gene

FULL NAME: Xeroderma pigmentosum group A-like


OTHER NAME(S):
CG6358
DhR14
DhXPA
Dmel\CG6358
dmXPA
DmXPA
dxpa
Dxpa
EG:EG0007.8
Xpa
XPAC
XPA_DROME


Nucleic acid sequence

        10         20         30         40         50         60
atgtctgcgg aggtctctac caacgaatct gctccgccgg cggagaagaa gtccaagctg
        70         80         90        100        110        120
accaatgccc aaaaggcgcg gatcgaaagg aaccaggcca aggcgcagaa attgcgggag
       130        140        150        160        170        180
gccaagttgg tttcgcatcc attcaaggag ctggccagca acaaggaggg tggcacccat
       190        200        210        220        230        240
ccggaggcgg cgctcagcca gggaagctct gtgatcaagg tgcagggcac caagtacata
       250        260        270        280        290        300
gactccggcg ggggcttcct gctcgaacag cctgttatgc ccacgggcgt gggcccagcg
       310        320        330        340        350        360
ggcctcaata agtccgggga ggaggccccg ccgatcctgg acgacgccat tgctatacca
       370        380        390        400        410        420
gtgcagtacg aggagtgcct ggagtgcggc gacatgttcg ccgactccta tttgttcaac
       430        440        450        460        470        480
aacttcggac actcggtgtg cgacaagtgc cgggacaagg atgagcgcta cgcgctgatt
       490        500        510        520        530        540
acccgcaccg aggccaaggc ggagtacttg ctgaaggact gcgatttcga caagcgggag
       550        560        570        580        590        600
cccaagctgc ggtacataag ccgcaagaat ccgcacaacg tacgttgggg cgagatgaag
       610        620        630        640        650        660
ctgtatctgc atctgcagat tcaccagcgc gccctggagg tctggggtag cgaggaggag
       670        680        690        700        710        720
ctggtgcgcc agcacgaggc gcgcgaggac aagcgagagg agggcaaggc gcgcaagtac
       730        740        750        760        770        780
aacaagaaga tgaagcagct gcgcatggag gtgcgcagca gcatctacac caagaagacg
       790        800        810        820        830        840
cacgaagttc acgagcacga gttcgggccg gacacctacg atgaagagga ggacacctac
       850        860        870        880        890
acccacacct gcattacctg tccgtacagc gagacctacg agaagatgta g

Last modification date: Oct. 2, 2011