Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: Transcription initiation factor TFIID subunit 3


DESCRIPTION:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (By similarity).

STRUCTURE SIMILARITY:
Belongs to the TAF3 family.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MEETQIDELY FSLMRIFCSQ TLRAAGIDRT KVSLLNSFTD ITIRYIRLLS ETAMAKAEVG
        70         80         90        100        110        120
RRSCCDLGDL RLAMEEIGLL NGSEEDVKTL VEWFNGPQVA ELRRVSGFVQ DSETQVKPKD
       130        140        150
WLTSLIQKQI RVSGPERFYE TVFSASNEEE DVKDS  

Encoded by taf3 gene


Nucleic acid sequence

        10         20         30         40         50         60
atggaagaaa cacaaattga cgagctgtat ttctcgctaa tgaggatttt ctgttctcag
        70         80         90        100        110        120
acacttcgcg cagctggcat tgaccgaacg aaggtttcat tattaaactc ttttactgat
       130        140        150        160        170        180
attactatcc ggtatattag acttctttca gaaaccgcta tggcaaaagc tgaagttggc
       190        200        210        220        230        240
aggaggagct gttgcgattt gggcgatctg cgtcttgcaa tggaagaaat tggtttgtta
       250        260        270        280        290        300
aatggctctg aagaagatgt taaaacgtta gtagaatggt ttaatggtcc acaggttgcg
       310        320        330        340        350        360
gaacttcgtc gggtatctgg atttgttcaa gacagtgaaa cgcaagtcaa acctaaagac
       370        380        390        400        410        420
tggcttacaa gcttaattca aaaacagatt cgtgtcagcg gccctgaaag attttatgag
       430        440        450        460
actgtatttt ctgcttctaa cgaagaagaa gacgtcaaag atagttaa 

Last modification date: Oct. 2, 2011