Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: Transcription initiation factor TFIID subunit 3


DESCRIPTION:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.

MISCELLANEOUS:
Present with 3300 molecules/cell in log phase SD medium.


STRUCTURE SIMILARITY:
Belongs to the TAF3 family.
Contains 1 histone-fold domain.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MTTNNDFYFA LLRISILQLL KAQGFDRARP SLVDVMTDLY AKFLSLLASE VSSIAQARCD
        70         80         90        100        110        120
QDDTIALQDI TLALENLGIV KPTNVLDVYD ENSELSSSRG MEKFKDWCIY STQLTDARIT
       130        140        150        160        170        180
ALPTVELLQS EEKESDPLSA IPDYLNQLLQ NKGAKQKLET KNRKTELIED LINNNGLDDW
       190        200        210        220        230        240
IKLVIARQRI NMIERASKKE SQNVPALPHI AGYKSSILSR HHHTTITNED RMPSAMTPRD
       250        260        270        280        290        300
EDALTEIQEN PFVTSKLPIM RKENRLENIT LSFEDEELES LGEVEGPNQK SQENNNEESF
       310        320        330        340        350
KENNKSLTES PHGDDRDISM FQFDSNVDTK WAEQEDMDST FQRRTSLDYG GYF

Encoded by TAF3 gene


OTHER NAME(S):
TAF47


Nucleic acid sequence

        10         20         30         40         50         60
atgactacaa ataatgactt ctattttgct ctactacgca tatctattct ccaattattg
        70         80         90        100        110        120
aaggcacaag gatttgacag ggcaaggccc agtctggtgg atgtcatgac cgatctctat
       130        140        150        160        170        180
gcaaaattct tgagtttgtt agcatcagag gtcagttcta tcgctcaggc aagatgtgat
       190        200        210        220        230        240
caggacgata caattgcttt acaagatata actctggctc tggaaaatct aggtattgtt
       250        260        270        280        290        300
aagcctacga acgttctgga tgtctatgat gaaaactccg aattatcaag ttcacgagga
       310        320        330        340        350        360
atggaaaagt tcaaggactg gtgtatttat agtactcaat tgaccgacgc gcgaataact
       370        380        390        400        410        420
gccttaccca cagtagaatt actacaaagt gaggaaaaag aatctgatcc tttgtcagca
       430        440        450        460        470        480
atacctgact atctcaatca attactgcaa aacaagggtg cgaaacagaa attagaaaca
       490        500        510        520        530        540
aagaatagaa aaacagagtt gatagaagat ctaataaata ataatggatt agatgattgg
       550        560        570        580        590        600
atcaaattag tcattgctag acaacgtata aacatgattg aaagagcttc caaaaaagaa
       610        620        630        640        650        660
tctcaaaatg taccggcttt accacatatt gcaggctata aatcttccat tctaagccgc
       670        680        690        700        710        720
catcaccaca ctaccataac aaacgaagat aggatgcctt cggcgatgac cccaagagat
       730        740        750        760        770        780
gaggatgcct taacagagat ccaagaaaat ccatttgtaa ctagcaaact gccgataatg
       790        800        810        820        830        840
agaaaagaaa ataggttaga aaatataact ctttcatttg aggatgagga gcttgaatca
       850        860        870        880        890        900
cttggcgaag tggaaggccc taaccaaaag tctcaagaaa ataacaatga ggaaagtttt
       910        920        930        940        950        960
aaagagaaca ataaaagttt aacagagtct cctcatggtg atgaccgtga catatcaatg
       970        980        990       1000       1010       1020
tttcaattcg actcaaatgt tgatactaaa tgggcagagc aggaagatat ggacagcaca
      1030       1040       1050       1060
tttcaacgtc gaacctcact agattatggg ggttactttt aa 

Last modification date: Oct. 2, 2011