Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: Transcription initiation factor TFIID subunit 8


DESCRIPTION:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.

MISCELLANEOUS:
Present with 4684 (+/-522) molecules/cell in log phase SD medium.


STRUCTURE SIMILARITY:
Belongs to the TAF8 family.
Contains 1 histone-fold domain.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MTSKTSESGT GTQSTIVQLR NLPDLTEISH LEIDAPVVEI LKKTVLFQLN SLNICISNFA
        70         80         90        100        110        120
LDELVNLVTV QMDGMFRNLH NLTLLQRRSQ ASQADLKLLL REFNLDAPSL YQQFQASEFI
       130        140        150        160        170        180
KSKHSTEYEK LMSWSSLAAL PHNEEDEEDE LNNIEEQQNE INVLLPPSNP LEKQIPSWLP
       190        200        210        220        230        240
NFPPDHTYKF TPEFNHPITD LKTIKKEIVK ESQESEKALL NLNKSLSHIS SASNTPQPPG
       250        260        270        280        290        300
LDDEDAIEQQ LEIWGNALEE RKPTITEKSF NENNIEQYAK YRVELARERV TKFEVNQLKR
       310        320        330        340        350        360
TKNPFLKISE TLYLPESPHQ SHKTIQKTIE LQFRKSMTLF MHNLPKVQKL KKEKIRMAKE
       370        380        390        400        410        420
ERAKSLKRRQ EELISQRTKR EQDEGHDLEL LLNNEHARDA ADDTTTPNAL NNSTIVINTN
       430        440        450        460        470        480
AEDEDDDINL FGILGSSEDE NEMSSMPAEN LVAESEPPTM TAQDTTNTTP VAHNTTNIDA
       490        500        510
TTSHSPHSTP NENAPTSPPA DIATDHDITM   

Encoded by TAF8 gene


OTHER NAME(S):
TAF65


Nucleic acid sequence

        10         20         30         40         50         60
atgacttcca aaacgtcaga aagtggtacc ggtacccaaa gtaccatagt tcagctgagg
        70         80         90        100        110        120
aacctaccgg atttgacgga aattagtcac ttggaaatag atgctcccgt agttgaaatt
       130        140        150        160        170        180
ctaaagaaaa cagtactttt ccagttgaat tcgttgaaca tctgcatttc aaactttgca
       190        200        210        220        230        240
ttggatgagc tggtcaacct cgtgaccgtc caaatggacg gcatgtttcg gaacctgcac
       250        260        270        280        290        300
aatttaacac ttttacaaag aaggtcgcaa gcttctcaag cagatttgaa attgttgctt
       310        320        330        340        350        360
cgagagttta acctggatgc gccctccctt tatcagcagt ttcaggcctc agaattcatc
       370        380        390        400        410        420
aaatcgaagc attccacgga atatgaaaaa ttgatgagct ggtcgtctct tgctgcttta
       430        440        450        460        470        480
ccgcataacg aagaagatga agaggacgaa ttgaataata tcgaggagca acagaacgag
       490        500        510        520        530        540
atcaacgttt tgctgcctcc ctctaaccca ctggaaaaac agataccgag ttggctgccc
       550        560        570        580        590        600
aactttccgc ctgaccatac ctataagttt acacctgagt tcaaccatcc aattactgat
       610        620        630        640        650        660
ctaaaaacca tcaagaaaga aatagtaaaa gaaagccaag agtctgaaaa ggcactattg
       670        680        690        700        710        720
aacttgaaca aaagtctctc ccacatatca tcagcgtcaa ataccccgca accgccgggt
       730        740        750        760        770        780
ttagacgatg aggacgctat cgagcaacaa ttggagattt ggggcaacgc gctggaagaa
       790        800        810        820        830        840
aggaaaccaa ccataactga aaagtccttc aatgaaaaca atatcgagca gtatgcgaag
       850        860        870        880        890        900
tatagagtgg aattggcgag agaacgtgtc acgaaatttg aagtgaatca gttgaaaaga
       910        920        930        940        950        960
acaaaaaatc cattcttgaa aatttctgaa actctctacc ttccagagag tcctcaccag
       970        980        990       1000       1010       1020
tctcacaaaa ccatacaaaa aaccatagaa ttgcaatttc gtaagtctat gacactattc
      1030       1040       1050       1060       1070       1080
atgcacaatt tacctaaggt ccagaagttg aagaaggaaa aaatacgaat ggccaaggaa
      1090       1100       1110       1120       1130       1140
gaaagagcaa aatcgctaaa acgtcggcaa gaagagctta tttcacaacg aacaaagagg
      1150       1160       1170       1180       1190       1200
gaacaagatg aaggccatga tcttgagctt ctactaaata acgagcacgc aagggacgct
      1210       1220       1230       1240       1250       1260
gcagacgaca cgaccacccc taatgcatta aacaactcta ccatagttat caacacaaac
      1270       1280       1290       1300       1310       1320
gccgaggatg aggacgatga cataaactta tttggcatct tagggagcag tgaagatgag
      1330       1340       1350       1360       1370       1380
aatgaaatgt cgagtatgcc tgcggagaac ctggtcgcgg aatcggaacc gccaacaatg
      1390       1400       1410       1420       1430       1440
acagcgcaag atactacaaa tactacacct gtagcacata acacaaccaa tatcgatgct
      1450       1460       1470       1480       1490       1500
actacaagtc actctcctca ttcgacgcct aatgaaaacg ccccgacatc tcctcctgca
      1510       1520       1530
gatatagcca cagatcacga tataactatg taa  

Last modification date: Oct. 2, 2011