Escherichia coli Migula (bacterium) K-12 MG1655 [ECO]

FULL NAME: DNA polymerase III subunit psi


DESCRIPTION:
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

CATALYTIC ACTIVITY:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


PROTEIN TYPE(S):
accessory protein


RELATED PATHWAY(S):
DNA replication
mismatch repair (MMR)
homologous recombination (HR)


Amino acids sequence

        10         20         30         40         50         60
MTSRRDWQLQ QLGITQWSLR RPGALQGEIA IAIPAHVRLV MVANDLPALT DPLVSDVLRA
        70         80         90        100        110        120
LTVSPDQVLQ LTPEKIAMLP QGSHCNSWRL GTDEPLSLEG AQVASPALTD LRANPTARAA
       130
LWQQICTYEH DFFPRND    

Encoded by holD gene


OTHER NAME(S):
ECK4363
JW4334


DESCRIPTION:
The preinitiation complex binds primed ssDNA and loads the beta processivity clamp. [More information is available at EcoCyc: EG11414].


Nucleic acid sequence

        10         20         30         40         50         60
atgacatccc gacgagactg gcagttacag caactgggca ttacccagtg gtcgctgcgt
        70         80         90        100        110        120
cgccctggcg cgttgcaggg ggagattgcc attgcgatcc cggcacacgt ccgtctggtg
       130        140        150        160        170        180
atggtggcaa acgatcttcc cgccctgact gatcctttag tgagcgatgt tctgcgcgca
       190        200        210        220        230        240
ttaaccgtca gccccgacca ggtgctgcaa ctgacgccag aaaaaatcgc gatgctgccg
       250        260        270        280        290        300
caaggcagtc actgcaacag ttggcggttg ggtactgacg aaccgctatc actggaaggc
       310        320        330        340        350        360
gctcaggtgg catcaccggc gctcaccgat ttacgggcaa acccaacggc acgcgccgcg
       370        380        390        400        410
ttatggcaac aaatttgcac atatgaacac gatttcttcc ctcgaaacga ctga

Last modification date: Oct. 2, 2011