Mus musculus L. (mouse) [MMU]

FULL NAME: General transcription factor IIE subunit 1


DESCRIPTION:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

STRUCTURE SIMILARITY:
Contains 1 HTH TFE/IIEalpha-type domain.
Belongs to the TFIIE alpha subunit family.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MADPDVLTEV PAALKRLAKY VIRGFYGIEH VLALDILIRN PCVKEEDMLE LLKFDRKQLR
        70         80         90        100        110        120
SVLNNLKGDK FIKCRMRVET AADGKTTRHN YYFINYRTLV NVVKYKLDHM RRRIETDERN
       130        140        150        160        170        180
STNRASFKCP VCCSTFTDLE ANQLFDPMTG TFRCTFCHTE VEEDESAMPK KDARTLLARF
       190        200        210        220        230        240
NEQIEPIYAL LRETEDVNLA YEILEPEPTE IPALKQSKDR AATAAGAAGL AGGHHREAWT
       250        260        270        280        290        300
NKGPSYEDLY TQNVVINMDD QDDVHRPSLE GKAAKERPIW LRESTVQGAY SSEEMKEGGI
       310        320        330        340        350        360
DVDTFQEREE ARAGPDDNEE VMRALLIHEK KTSSVTAGSV GAAAPVTAAN GSDSESETSE
       370        380        390        400        410        420
SDDDSPPRPA AAAPPHHHRD EDEEDEEFEE VADDPIVMVA GCPFSYSEVS QRPELVAQMT
       430        440
PEEKEAYIAM GQRMFEDLFE    

Encoded by Gtf2e1 gene

FULL NAME: general transcription factor II E, polypeptide 1 (alpha subunit)


OTHER NAME(S):
2610024P03Rik
56kDa
AI303800
FE
TFIIE-A


Nucleic acid sequence

        10         20         30         40         50         60
atggcagacc cagatgttct cactgaagtt ccggcggcat tgaagcggct agccaagtat
        70         80         90        100        110        120
gtcatccggg gcttttatgg cattgagcac gtgttggcct tggacatctt gatccggaac
       130        140        150        160        170        180
ccctgtgtaa aagaagagga catgctggag ctgctcaagt ttgatcggaa gcaacttcga
       190        200        210        220        230        240
tccgttttga ataatttaaa gggagacaag ttcatcaaat gcagaatgag ggtagagact
       250        260        270        280        290        300
gctgcagatg ggaagaccac ccgccataac tactacttca tcaattaccg cactcttgtt
       310        320        330        340        350        360
aatgtagtga aatataagct ggaccacatg agaagaagga ttgaaacaga tgagagaaat
       370        380        390        400        410        420
tccaccaatc gggcttcctt caaatgtcct gtctgctgca gcactttcac tgacctagaa
       430        440        450        460        470        480
gccaatcaac tgtttgatcc catgacagga actttccgct gcaccttttg ccatacagag
       490        500        510        520        530        540
gtagaagaag atgaatcagc aatgcccaaa aaagatgctc gcacgctttt ggcaagattt
       550        560        570        580        590        600
aatgaacaaa ttgagcccat ttatgcattg cttcgggaga cagaggatgt aaacttggcc
       610        620        630        640        650        660
tatgaaatac ttgaaccaga acccacagaa atcccagcac tgaagcaaag caaggaccga
       670        680        690        700        710        720
gcagcaactg ctgctggagc tgctggcctg gcaggtgggc accaccgaga ggcgtggacc
       730        740        750        760        770        780
aacaaaggcc cctcgtatga ggacttgtat actcagaatg ttgtcattaa catggatgat
       790        800        810        820        830        840
caagatgatg tgcatcgccc ctcgctggaa gggaaagctg ccaaagagag acccatttgg
       850        860        870        880        890        900
ttgagagaga gcactgtcca aggggcatac agttctgaag agatgaagga aggtggcatc
       910        920        930        940        950        960
gatgtggaca catttcagga gcgcgaggaa gcccgtgcgg ggcctgatga caatgaggag
       970        980        990       1000       1010       1020
gtcatgcgag ctctactcat tcatgagaag aagacttcct cggtgacagc tggctctgtg
      1030       1040       1050       1060       1070       1080
ggagcagccg ctccggtgac agctgctaat ggcagtgact ctgagagtga gaccagcgag
      1090       1100       1110       1120       1130       1140
tcagatgatg actctccacc tcggccagca gctgcggctc ctcctcatca tcatcgcgat
      1150       1160       1170       1180       1190       1200
gaagatgagg aagacgagga gtttgaggaa gtagcagatg accccattgt tatggtggct
      1210       1220       1230       1240       1250       1260
ggctgtccat tttcctacag tgaagttagc cagcggccgg agctggtggc ccagatgacc
      1270       1280       1290       1300       1310       1320
ccagaagaga aggaagcata catagccatg ggccagcgta tgtttgagga tctctttgag

tga     

Last modification date: Oct. 2, 2011