Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: Transcription initiation factor IIE subunit alpha


DESCRIPTION:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity).

STRUCTURE SIMILARITY:
Contains 1 HTH TFE/IIEalpha-type domain.
Belongs to the TFIIE alpha subunit family.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MSNAPEIVQR LIKMIMRAFY ETRHIIFMDA ILRHSAYVLH KIRTILTFGR LTDEQTALLM
        70         80         90        100        110        120
GIPIKECRFI AGKLREDRLL AIQSRTEMKE GQQRQYHTTY FYIDFCSTID SIKWRMHQLV
       130        140        150        160        170        180
KTVEDRMRND FDSKGYVCPF CNKKFSSLDV LSLVTNEGTF ACNVCGTELK DDEESAEMMS
       190        200        210        220        230        240
SQKRLGKLMG QVNGIIDALK RVDEIVVPQN NFQSALEHAV PVSLDTQNLS QQNLSKSNSD
       250        260        270        280        290        300
VRLSTSSPSI TVDFSADKET DEKRERNCDK QVKAAQNILP EWHATSTISG SITRAGAKDA
       310        320        330        340        350        360
ALHSFRTETV NEVQDTKTDI TSEKSALDAY YATLRAKQKE ESEFMDSENV DDEEDDDFLD
       370        380        390        400        410        420
VTTATSLQNK STDYGSVKRK TENLNSDSDI QNKRTKSIEE NNSLPPIVST NGITDGDTEM
       430        440
QESKKNVIIN GFNEDDEDDE DEADFEDV   

Encoded by tfa1 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgtccaatg ctccagaaat agtacagaga cttataaaaa tgattatgag ggcgttttac
        70         80         90        100        110        120
gaaactagac atataatatt tatggatgcg attttgcgac attcagcgta cgtgcttcac
       130        140        150        160        170        180
aagatcagaa cgattttaac ctttggtaga cttacagatg agcaaacagc gctgttaatg
       190        200        210        220        230        240
ggtatcccta taaaagaatg tcggtttatt gctggaaaat tgcgcgagga tcgtttattg
       250        260        270        280        290        300
gcaattcaaa gtaggacgga aatgaaggaa ggccaacaaa ggcaatatca tacaacctat
       310        320        330        340        350        360
ttctatatcg atttctgttc tacgattgac agcattaaat ggcgtatgca ccaattagtg
       370        380        390        400        410        420
aaaacagtag aagatcgaat gcgaaatgat ttcgattcta aaggctatgt ttgtccattt
       430        440        450        460        470        480
tgcaacaaaa agttttctag ccttgacgtt ttgtctttgg tgaccaacga gggaactttt
       490        500        510        520        530        540
gcttgtaacg tttgtggaac cgaactcaaa gacgatgagg agagtgcaga aatgatgtct
       550        560        570        580        590        600
agtcagaaaa ggctaggaaa actgatggga caagttaatg gtataatcga tgcattgaaa
       610        620        630        640        650        660
agggtggatg aaattgtcgt accacaaaac aatttccaat ctgctttaga acatgcggtt
       670        680        690        700        710        720
cctgtttcgt tagacaccca aaatttgtcg caacaaaact tgtcaaaaag taattcagac
       730        740        750        760        770        780
gtccgtcttt ccacctcttc gccatctatt acagttgatt tctctgctga taaagagact
       790        800        810        820        830        840
gatgaaaagc gtgaaaggaa ttgcgacaag caagtcaaag ctgctcaaaa cattcttccc
       850        860        870        880        890        900
gaatggcatg caacatcaac aatttctggc tccattactc gtgctggagc taaagatgcc
       910        920        930        940        950        960
gcacttcata gttttagaac tgaaactgtt aatgaggttc aagacactaa aacagatatt
       970        980        990       1000       1010       1020
acttctgaaa agagcgcctt agatgcttat tacgcaacac ttcgtgcaaa gcaaaaagag
      1030       1040       1050       1060       1070       1080
gaaagcgagt ttatggacag tgaaaacgta gatgatgagg aggatgatga cttcttagac
      1090       1100       1110       1120       1130       1140
gttacgacgg ctacctctct tcaaaacaaa agtactgatt atgggtcggt caagcgtaaa
      1150       1160       1170       1180       1190       1200
accgagaacc taaattcaga tagtgatatc caaaataaaa gaacaaaatc gatagaagaa
      1210       1220       1230       1240       1250       1260
aacaattcat taccacctat tgtttctaca aatggtatta ctgatggtga tacggaaatg
      1270       1280       1290       1300       1310       1320
caagaaagta aaaagaatgt tattattaat ggatttaatg aggacgatga agacgatgaa
      1330       1340
gatgaagctg attttgaaga tgtttaa   

Last modification date: Oct. 2, 2011