Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: Transcription initiation factor IIE subunit alpha


DESCRIPTION:
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity).

MISCELLANEOUS:
Present with 35900 molecules/cell in log phase SD medium.


STRUCTURE SIMILARITY:
Contains 1 HTH TFE/IIEalpha-type domain.
Belongs to the TFIIE alpha subunit family.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MDRPIDDIVK NLLKFVVRGF YGGSFVLVLD AILFHSVLAE DDLKQLLSIN KTELGPLIAR
        70         80         90        100        110        120
LRSDRLISIH KQREYPPNSK SVERVYYYVK YPHAIDAIKW KVHQVVQRLK DDLDKNSEPN
       130        140        150        160        170        180
GYMCPICLTK YTQLEAVQLL NFDRTEFLCS LCDEPLVEDD SGKKNKEKQD KLNRLMDQIQ
       190        200        210        220        230        240
PIIDSLKKID DSRIEENTFE IALARLIPPQ NQSHAAYTYN PKKGSTMFRP GDSAPLPNLM
       250        260        270        280        290        300
GTALGNDSSR RAGANSQATL HINITTASDE VAQRELQERQ AEEKRKQNAV PEWHKQSTIG
       310        320        330        340        350        360
KTALGRLDNE EEFDPVVTAS AMDSINPDNE PAQETSYQNN RTLTEQEMEE RENEKTLNDY
       370        380        390        400        410        420
YAALAKKQAK LNKEEEEEEE EEEDEEEEEE EEMEDVMDDN DETARENALE DEFEDVTDTA
       430        440        450        460        470        480
GTAKTESNTS NDVKQESIND KTEDAVNATA TASGPSANAK PNDGDDDDDD DDDEMDIEFE

DV     

Encoded by TFA1 gene


Nucleic acid sequence

        10         20         30         40         50         60
atggatagac ctatagatga tattgtgaaa aatcttttaa agttcgtcgt tagggggttt
        70         80         90        100        110        120
tatggtggct cctttgtact ggtactcgat gctatactat ttcactcggt cctagctgaa
       130        140        150        160        170        180
gatgacttga aacaattgtt gagcataaat aagacggaac tggggccgct aattgctaga
       190        200        210        220        230        240
ctaagatcag acaggttaat atccatacac aaacaaagag aataccctcc aaactcaaaa
       250        260        270        280        290        300
agtgtggaaa gagtttacta ctatgtaaaa tatcctcatg ctattgacgc aatcaaatgg
       310        320        330        340        350        360
aaggtccatc aagtcgtaca aagattgaag gatgacttgg acaaaaattc agaacctaat
       370        380        390        400        410        420
ggttacatgt gtccgatttg tttgaccaag tacacacaat tggaagctgt acaattattg
       430        440        450        460        470        480
aattttgata ggacagaatt tttatgttcc ctatgtgatg aaccgttggt ggaagatgat
       490        500        510        520        530        540
tctggtaaaa aaaacaaaga gaagcaagat aaattaaata ggttaatgga ccaaattcag
       550        560        570        580        590        600
ccaatcattg attctttgaa aaagattgat gattcaagaa ttgaggagaa tactttcgaa
       610        620        630        640        650        660
attgcattgg ctcgcttgat accacctcaa aatcaatcac atgcagcata cacgtacaat
       670        680        690        700        710        720
ccaaagaaag gcagcaccat gttcagaccg ggagattctg ctccattgcc aaatcttatg
       730        740        750        760        770        780
ggtactgctc ttggtaacga cagtagtaga cgtgccggtg ctaactctca agccacatta
       790        800        810        820        830        840
cacatcaaca ttaccacggc aagtgatgaa gtggctcaaa gggaattgca agagagacag
       850        860        870        880        890        900
gctgaagaga aaagaaaaca aaacgctgtc cctgaatggc ataaacagag taccatcggt
       910        920        930        940        950        960
aaaactgctc ttggtagact ggataatgaa gaggagttcg atcctgtagt tactgcatct
       970        980        990       1000       1010       1020
gccatggatt ctataaatcc tgataatgaa cctgcacagg aaacatccta tcaaaataac
      1030       1040       1050       1060       1070       1080
agaactctga ccgagcaaga aatggaagaa agagagaatg aaaagacgtt gaatgattac
      1090       1100       1110       1120       1130       1140
tacgctgctt tggctaaaaa gcaagcaaag ctcaataaag aagaagagga ggaggaagaa
      1150       1160       1170       1180       1190       1200
gaagaagagg atgaggaaga agaagaggaa gaagagatgg aagatgttat ggatgataac
      1210       1220       1230       1240       1250       1260
gatgaaactg ctagagaaaa tgcattggaa gatgaatttg aagacgtaac ggatacagct
      1270       1280       1290       1300       1310       1320
ggcaccgcaa agacagaatc aaacacctcc aacgacgtaa aacaagaatc gattaatgat
      1330       1340       1350       1360       1370       1380
aagactgaag acgctgtaaa tgctactgcc actgcttcag gtccgagtgc aaacgctaaa
      1390       1400       1410       1420       1430       1440
ccaaatgatg gtgatgatga tgatgatgat gatgatgatg agatggacat tgagtttgag

gacgtttga     

Last modification date: Oct. 2, 2011