Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: Transcription initiation factor TFIID subunit 11


DESCRIPTION:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (By similarity).

STRUCTURE SIMILARITY:
Belongs to the TAF11 family.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MKRTGSASSV PRFQRSMSYD QSNSPTAGAH AKANTASPAA EPAPSSKEKE NWNRQEENDL
        70         80         90        100        110        120
EEDDRDDFGT AAISKVAGKP GETDDEANEK LRTKYLLESF DEEQMQRYEV FRRANLNKTN
       130        140        150        160        170        180
VKKLANQILN QSVTPNVAIV ISGFSKVFVG EIVELARKIQ DQWGDTGPLS PDHLREAYRL
       190
SRQNRRLYPQ SRHVSHLFR    

Encoded by taf11 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgaaacgaa ctggttctgc gagttcagta cctcgatttc agcgatcgat gagctacgat
        70         80         90        100        110        120
caatctaatt ctcctacagc aggagctcat gcaaaggcaa atacggcatc gcctgctgct
       130        140        150        160        170        180
gagcctgctc cctcatcaaa agaaaaagag aattggaatc ggcaagaaga aaatgatctg
       190        200        210        220        230        240
gaagaagacg atagggatga ctttggtaca gctgctattt caaaagttgc tggaaaacct
       250        260        270        280        290        300
ggtgaaacgg acgacgaagc taatgaaaaa ttgcgcacaa aatatcttct agagagtttt
       310        320        330        340        350        360
gatgaagagc aaatgcaaag atacgaagtg tttcgtcgtg ctaacttaaa taaaaccaat
       370        380        390        400        410        420
gttaaaaaat tggctaacca aattttaaac caaagtgtaa cccccaatgt tgctattgtg
       430        440        450        460        470        480
atctcaggat tttcaaaggt gtttgttgga gaaatcgttg aattagctcg aaagattcaa
       490        500        510        520        530        540
gatcaatggg gggatactgg tccactgagt cctgatcatt tacgagaggc gtatagatta
       550        560        570        580        590        600
tcacgtcaaa atcggaggct ttatccacag agccgtcatg ttagtcattt gtttcggtga

Last modification date: Oct. 2, 2011