Mus musculus L. (mouse) [MMU]

FULL NAME: TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L


DESCRIPTION:
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex (By similarity).

STRUCTURE SIMILARITY:
Belongs to the TAF6 family.


POST-TRANSLATIONAL MODIFICATION:
Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity).


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MQSSTGAMSE REERRFVEIP RESVRLMAES TGLELSDEVA ALLAEDVCYR LREATQNSSQ
        70         80         90        100        110        120
FMKHTKRRKL TVEDFNRALR WSSVEAVCGY GSQEALPLRP AREGDLYFPE DREVSLVELA
       130        140        150        160        170        180
LATNIPKGCA ETAVRVHVSY LDGKGNLAPQ GSVPSAVSSL TDDLLKYYQQ VTRAVLGDDP
       190        200        210        220        230        240
QLMKVKSVSH DLEQLHRLLQ VARSLIRNPH LCLGPYVRSL VGSVLYCVLE PLAASINPLN
       250        260        270        280        290        300
DHWTLRDGAA LLLSHIFWTH GDLVSGLYQQ ILLSLQKVLT DPVRPLCSHY GAVVGLHALG
       310        320        330        340        350        360
WKAVERVLYP HLPTYWTNLQ AVLDDYSVSN AQVKADGHKV YGAILVAVER LLKMKAQAAE
       370        380        390        400        410        420
PNRGGLGGRG YRPAEDLPWD SLLLQESPPG GSSETGFGSG LPPPSGVAGP EDPSSLTLAD
       430        440        450        460        470        480
IYRELYSFFG DSLATRFGTG QPAPTAPRPP GDKKEPAAAP DSVRKMPQLT ASAVVSPQGD
       490        500        510        520        530        540
ESPCGGTLAT ATAASESRPL PRVHRARGAP RQQGPGAGTR DVFQKSRFAP RGAPHFRFII
       550        560        570        580        590
AGRQAGRRCR GRLFQTAFPA PYGPSPASRY VQKLPMIGRT GRPARRWALS DYSLYLPL

Encoded by Taf6l gene

FULL NAME: TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor


OTHER NAME(S):
2810417N14Rik
BB223262
C530024J06Rik
MGC41377
Paf65a


Nucleic acid sequence

        10         20         30         40         50         60
atgcaaagtt ccaccggggc catgtcagaa cgagaggaga ggaggtttgt ggagatccct
        70         80         90        100        110        120
cgggagtcgg tccggctcat ggcagagagc acaggtctag agctgagtga cgaggtggcc
       130        140        150        160        170        180
gctctgctcg ctgaagatgt gtgctaccgt ctccgagagg ccacacagaa tagctctcaa
       190        200        210        220        230        240
ttcatgaaac acaccaaacg aaggaagctg acggtggagg acttcaacag ggctctcagg
       250        260        270        280        290        300
tggagcagcg tggaggctgt gtgtggctat gggtcccagg aggcattgcc cttgcgccct
       310        320        330        340        350        360
gcaagggagg gtgatctcta cttcccggag gatcgagaag tgagcctggt ggagctggca
       370        380        390        400        410        420
ctagccacca acatccccaa gggctgtgca gagacagctg tcagagttca tgtctcctat
       430        440        450        460        470        480
ctggatggca aaggaaacct ggcacctcag ggatcagtgc ccagtgcagt gtcttcactg
       490        500        510        520        530        540
acagatgacc tgctcaaata ctaccagcaa gtgacacggg ctgtactggg agatgaccca
       550        560        570        580        590        600
cagctgatga aggtaaaatc tgtaagccac gacctggaac aactgcaccg actactgcag
       610        620        630        640        650        660
gtggcaagga gcctgatacg gaacccacac ctgtgcttgg gaccctatgt ccgatccttg
       670        680        690        700        710        720
gtgggcagcg tgctttactg tgtcttggag ccactggccg cctccatcaa ccctttgaat
       730        740        750        760        770        780
gaccactgga ctctgcgaga tggggctgcc cttctactca gtcacatatt ctggacgcat
       790        800        810        820        830        840
ggagaccttg taagtggcct gtatcagcag attctgctgt ccctgcagaa ggtcctgaca
       850        860        870        880        890        900
gaccctgttc ggcctctctg ttctcactat ggggcagtgg tggggctgca tgctctaggc
       910        920        930        940        950        960
tggaaggcag tggagcgagt cctctaccca catctgccca cttactggac aaacttgcag
       970        980        990       1000       1010       1020
gctgtgctgg atgactattc cgtatctaat gcccaggtca aagcggacgg gcacaaagtg
      1030       1040       1050       1060       1070       1080
tatggagcca ttctggtggc cgtagaacga ctattgaaga tgaaagctca ggcagcagag
      1090       1100       1110       1120       1130       1140
cccaaccgcg gtggccttgg cgggagaggg taccgtcctg cggaggacct gccttgggac
      1150       1160       1170       1180       1190       1200
agccttctcc tacaagaatc tccccccggg ggcagctccg aaacaggttt tgggtctggt
      1210       1220       1230       1240       1250       1260
ctcccgccac catcaggggt tgcgggacca gaggaccctt cttccttgac cctggcagac
      1270       1280       1290       1300       1310       1320
atctaccgtg agctatactc cttctttggt gacagcttgg ccactcgctt tggcactggc
      1330       1340       1350       1360       1370       1380
cagcctgctc ccacggcccc gcgaccaccc ggagacaaga aggagcctgc ggctgccccg
      1390       1400       1410       1420       1430       1440
gattcggtgc ggaaaatgcc gcagctgact gccagcgccg tggtcagccc tcagggtgac
      1450       1460       1470       1480       1490       1500
gaaagcccgt gcggtgggac tctcgccacc gccaccgccg cctcggagag caggccgcta
      1510       1520       1530       1540       1550       1560
ccgcgcgtac accgggcgcg gggtgctcct cgtcagcagg gccccggcgc gggaacgcga
      1570       1580       1590       1600       1610       1620
gacgtcttcc agaagagccg cttcgcgccc cgtggcgccc cacacttccg gtttataatc
      1630       1640       1650       1660       1670       1680
gcagggcgtc aggccgggcg gcgctgccgc gggcgcctct ttcaaactgc ctttcctgcc
      1690       1700       1710       1720       1730       1740
ccatatgggc ccagccccgc gtcccgctac gtgcagaagc tgcccatgat cggccgtacc
      1750       1760       1770       1780       1790
ggccgcccgg cccgccgctg ggcgctctcc gactactcgc tgtacctgcc gctgtga

Last modification date: Oct. 2, 2011