Mus musculus L. (mouse) [MMU]

FULL NAME: Transcription initiation factor TFIID subunit 5


DESCRIPTION:
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed (By similarity).

STRUCTURE SIMILARITY:
Belongs to the WD repeat TAF5 family.
Contains 12 WD repeats.
Contains 1 LisH domain.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MAALAEEQTE VAVKLEPEGP PTLLPPQAGD GAGEGSGGTP NNGPNGGGGG NVAVAAAAGG
        70         80         90        100        110        120
DGGTPKPGVA VSAAAPAGAA PVPAAPAEAG APHDRQTLLA VLQFLRQSNL REAEEALRRE
       130        140        150        160        170        180
ARLLEEAVAG SGAPGELDGA GAEAASALLS RVTASVPGSA APEPPGTGAS VTSVFSGSAS
       190        200        210        220        230        240
GPAAPGKVAS VAVEDQPDVS AVLSAYNQQG DPTMYEEYYS GLKHFIECSL DCHRAELSQL
       250        260        270        280        290        300
FYPLFVHMYL ELVYNQHENE AKSFFEKFHG DQECYYQDDL RVLSSLTKKE HMKGNETMLD
       310        320        330        340        350        360
FRTSKFVLRI SRDSYQLLKR HLQEKQNNQI WNIVQEHLYI DIFDGMPRSK QQIDAMVGSL
       370        380        390        400        410        420
AGEAKREANK SKVFFGLLKE PEIEVPLDDE DEEGENEEGK PKKKKPKKDS IGSKSKKQDP
       430        440        450        460        470        480
NAPPQNRIPL PELKDSDKLD KIMNMKETTK RVRLGPDCLP SICFYTFLNA YQGLTAVDVT
       490        500        510        520        530        540
DDSSLIAGGF ADSTVRVWSV TPKKLRSVKQ ASDLSLIDKE SDDVLERIMD EKTASELKIL
       550        560        570        580        590        600
YGHSGPVYGA SFSPDRNYLL SSSEDGTVRL WSLQTFTCLV GYKGHNYPVW DTQFSPYGYY
       610        620        630        640        650        660
FVSGGHDRVA RLWATDHYQP LRIFAGHLAD VNCTRFHPNS NYVATGSADR TVRLWDVLNG
       670        680        690        700        710        720
NCVRIFTGHK GPIHSLTFSP NGRFLATGAT DGRVLLWDIG HGLMVGELKG HTDTVCSLRF
       730        740        750        760        770        780
SRDGEILASG SMDNTVRLWD AVKAFEDLET DDFTTATGHI NLPENSQELL LGTYMTKSTP
       790        800
VVHLHFTRRN LVLAAGAYSP Q   

Encoded by Taf5 gene

FULL NAME: TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor


OTHER NAME(S):
6330528C20Rik
AV117817


Nucleic acid sequence

        10         20         30         40         50         60
atggcggcgc tggcggagga gcagacggag gtggcggtca agctagagcc tgagggaccg
        70         80         90        100        110        120
ccgacgctgc tacctccgca ggctggcgac ggcgcaggcg aggggagcgg cggcactccc
       130        140        150        160        170        180
aacaacggcc ccaacggcgg cggcggcggg aatgtggcag tggcagcggc ggccggcggg
       190        200        210        220        230        240
gacggcggga cccccaagcc tggggtggct gtctccgccg ctgccccggc gggggcggcc
       250        260        270        280        290        300
ccggtgcccg ccgctccggc ggaggccggc gctccccacg accgacagac cctcctggcc
       310        320        330        340        350        360
gtgctgcaat tcctccggca gagcaacctc cgcgaggccg aagaggcgct gcgccgggag
       370        380        390        400        410        420
gcccggctgc tggaggaggc ggtggcgggc tccggagctc cgggagagtt ggacggggcc
       430        440        450        460        470        480
ggcgcggagg cggccagcgc gcttctcagc cgggtcaccg cttcagttcc cggctctgcg
       490        500        510        520        530        540
gcccccgagc ctccggggac gggcgcctcg gtgacctcgg tgttctcggg ttcagcctca
       550        560        570        580        590        600
ggtcctgcgg ctccgggaaa ggttgcaagt gtagctgtgg aagaccagcc agacgtcagt
       610        620        630        640        650        660
gctgtcttgt cggcctacaa ccaacaagga gaccctacaa tgtatgaaga atactacagt
       670        680        690        700        710        720
ggactgaaac acttcattga atgttctctg gactgccatc gagcagagtt atcccaactc
       730        740        750        760        770        780
ttttatcctc tgtttgtaca tatgtacttg gagctagttt ataatcaaca tgaaaatgaa
       790        800        810        820        830        840
gcaaaatcat tctttgagaa gttccatgga gatcaggaat gttactacca ggatgaccta
       850        860        870        880        890        900
cgagtgttat ctagtcttac caaaaaggag cacatgaaag ggaacgagac catgctggac
       910        920        930        940        950        960
tttcggacga gtaaattcgt tctccgcatt tcccgggact cgtaccagct cttgaagcgg
       970        980        990       1000       1010       1020
catctccagg agaagcagaa caatcagatc tggaacatcg tgcaggagca cctctacatc
      1030       1040       1050       1060       1070       1080
gacatcttcg acgggatgcc tcgcagtaag caacagatcg acgccatggt gggcagcctg
      1090       1100       1110       1120       1130       1140
gcaggagagg cgaaacgaga ggcgaacaaa tcgaaggtat tttttggttt actaaaagaa
      1150       1160       1170       1180       1190       1200
ccagaaattg aggtgccttt ggatgatgag gacgaagaag gagaaaatga agaaggaaaa
      1210       1220       1230       1240       1250       1260
cctaaaaaga agaagcctaa gaaggatagt attggctcta aaagcaaaaa acaagatccc
      1270       1280       1290       1300       1310       1320
aatgccccgc ctcaaaacag aattcctctt cctgagttaa aagattcaga caaactggac
      1330       1340       1350       1360       1370       1380
aaaataatga atatgaaaga aactaccaaa cgagtgcgcc tcgggccaga ctgtttaccc
      1390       1400       1410       1420       1430       1440
tccatttgtt tctatacatt ccttaatgct taccagggcc tcactgcagt ggatgtcact
      1450       1460       1470       1480       1490       1500
gatgactcta gtctgattgc tggaggtttt gctgattcaa ctgtcagagt gtggtctgtg
      1510       1520       1530       1540       1550       1560
acccctaaaa agcttcgtag tgtcaaacaa gcatcagatc ttagtcttat agacaaagaa
      1570       1580       1590       1600       1610       1620
tcagatgatg tcttagagag aatcatggat gagaaaactg caagtgagtt gaagattttg
      1630       1640       1650       1660       1670       1680
tatggtcaca gtgggcctgt ctatggagcc agcttcagtc cggataggaa ctacctactc
      1690       1700       1710       1720       1730       1740
tcctcttcag aggatggaac tgttagactc tggagccttc agactttcac ttgcttggtt
      1750       1760       1770       1780       1790       1800
gggtataaag gacacaacta cccagtatgg gacacacagt tttctccata cggatattat
      1810       1820       1830       1840       1850       1860
ttcgtgtcag gaggccatga ccgagtagct cggctttggg ctaccgatca ctatcagcct
      1870       1880       1890       1900       1910       1920
ttgaggatat ttgctggcca tcttgctgat gtgaattgca ctagatttca tccaaattcg
      1930       1940       1950       1960       1970       1980
aactatgttg ctacgggctc tgcagacaga actgtgcggc tctgggatgt cctcaatggt
      1990       2000       2010       2020       2030       2040
aactgtgtaa gaatcttcac tgggcacaag ggaccaattc attccttgac attttctccc
      2050       2060       2070       2080       2090       2100
aatgggagat tcctggctac aggagcaaca gatggcagag tacttctttg ggatattgga
      2110       2120       2130       2140       2150       2160
cacggcttga tggttggaga attaaaaggc cacactgata cagtgtgttc acttaggttt
      2170       2180       2190       2200       2210       2220
agtagagatg gtgaaatttt ggcatcaggt tcaatggata atacagtccg gttatgggac
      2230       2240       2250       2260       2270       2280
gccgtcaaag cgtttgaaga cttagagact gatgacttta ctacagccac cgggcatata
      2290       2300       2310       2320       2330       2340
aacctacctg agaattccca ggagttgtta ttgggtacat atatgaccaa atcaacacca
      2350       2360       2370       2380       2390       2400
gttgtacacc tacattttac aagaagaaac ttggttctag ctgcaggagc ttacagtccg

caataa     

Last modification date: Oct. 2, 2011