Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: Transcription initiation factor TFIID subunit 2


DESCRIPTION:
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.

MISCELLANEOUS:
Present with 1200 molecules/cell in log phase SD medium.


STRUCTURE SIMILARITY:
Belongs to the TAF2 family.


RELATED PATHWAY(S):
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MMSFSKNATP RAIVSESSTL HEMKFRNFRV AHEKISLDID LATHCITGSA TIIIIPLIQN
        70         80         90        100        110        120
LEYVTFDCKE MTIKDVLVEN RRCDQFIHDD PLQTNLNGLT SQNVLYSDNS IEQSHFLRSK
       130        140        150        160        170        180
FASLNEYPET DSKSQLTIKI PSSIKISLED ANALSNYTPI TPSIKTTPGF QESVFTPITL
       190        200        210        220        230        240
QIEYEIRNPK SGIKFDTVYA DKPWLWNVYT SNGEICSSAS YWVPCVDLLD EKSTWELEFS
       250        260        270        280        290        300
VPRLVKNIGT SKLIGQNGEE SEKEKEDTPE HDEEEEGKPA RVIKDEDKDS NLKNDEEGKN
       310        320        330        340        350        360
SKSKDAQDND EEEEEGESDE EEEEGEEERR NIEESNNPSL RDVIVCCSEY SNIKELPHPI
       370        380        390        400        410        420
DLTKKKCIFQ IINPVAPHHI GWAIGAFNSW SLPLISPPSV DAEDEVEEDK LRENVVDNVN
       430        440        450        460        470        480
DTMDDDIGSD IIPIQIFTLP TQETDELTVI NSTVVCQKII DFYSKEFGSY PFTCYSMVFL
       490        500        510        520        530        540
PTAPSKHMDF AALGICNTRL LYPLEVIDKA FSTTNELAWA LANQWSCVNI TPLDMNDYWC
       550        560        570        580        590        600
CLGIAGYMVF QVTKKLMGNN TYKYQLKRNS EAIVEQDFEK PPIGSTFTGS SRPISWSSKD
       610        620        630        640        650        660
LSFIQLKAPM ILHILDRRMT KTERSFGMSR VLPKIFLQAM SGDLPNNSLT SSHFQHVCER
       670        680        690        700        710        720
VNKSKLENFF NEWVYGSGVP ILRVTQRFNR KRMVIELGIR QVQDEELGHE KVVGEEGFFK
       730        740        750        760        770        780
SALDHLEHPD LNRTECFTGS MTIRIHEHDG TPYEHIVEIK DTFTKIDIQY NTKYRRLRKR
       790        800        810        820        830        840
GGGANDENGV ENNNEEKPIV VDVNCLGNVY MSPEECSRFS LTEFNRTSES NELLKQNEAF
       850        860        870        880        890        900
EWIRIDSDLE WICQMHINQP DYMFSSQLRQ DGDIEAQLEA IRYYEDVVVN GGVKSLVYSS
       910        920        930        940        950        960
ILFRTAIDER YFFGIRLAAC EALSKYVYDP DFTGGVKHLI QIFQILFCLE DSNIPKSNNF
       970        980        990       1000       1010       1020
ENPKLYFLQC NIPKYLAKVK NENGKCPKLV KQFLLDILVY NENGENKYSD DAYVRSLIEN
      1030       1040       1050       1060       1070       1080
VVKVALNEYK DKAYMEKVKT QLLRYENLVN WLSSYESLIK TTIMYAKYKL HKVGAYDFTE
      1090       1100       1110       1120       1130       1140
LTGMIMHTLT LGINNGDISR ESFQNEFLMV LKIMLLEGGL KNKDALVLFT EILCFHEDSY
      1150       1160       1170       1180       1190       1200
IRDKSVDVLS ECVNLVVMDG SLDTISDDIK SSVQSVHNEV KNIKSEDDIE LFLSGHYVDD
      1210       1220       1230       1240       1250       1260
MKIKIEKIGR QNISGLIQIC RDMFKGYSPL KILLWDVLNL PVLSLYQRKQ IHDLVRVMYT
      1270       1280       1290       1300       1310       1320
LINSFVVRLE TPRERRLVAK MNSNEEGKLD IVIKRESILK VHIKKEVTST VEAPKKANKI
      1330       1340       1350       1360       1370       1380
KISLKGDKPV RKVEKQIVKP KVTSKQRKVK SHVNRMGSLP LRFVKIQQQP RVMVHLSSVP
      1390       1400
YSQFVQITKV TSRSFMVKIR TKNDAKN   

Encoded by TAF2 gene


OTHER NAME(S):
TAF150
TSM1


Nucleic acid sequence

        10         20         30         40         50         60
atgatgtcct tttccaaaaa cgccactcct agagccattg ttagtgaatc tagcactttg
        70         80         90        100        110        120
catgagatga agtttagaaa ttttagagtt gcccatgaaa aaatctcgtt ggatatagat
       130        140        150        160        170        180
ctagctactc actgcattac cggtagcgct actataataa tcattccgtt gatccaaaac
       190        200        210        220        230        240
ctagaatatg taacttttga ttgcaaggaa atgactatta aagatgttct ggtcgaaaat
       250        260        270        280        290        300
cgtcgatgtg atcaatttat tcatgacgac ccacttcaaa caaatttgaa tggattgact
       310        320        330        340        350        360
tcacaaaatg tattatacag cgacaattcc attgaacagt cacatttttt gagatctaag
       370        380        390        400        410        420
tttgctagct tgaatgaata cccagaaacg gactctaaat cccagttaac tataaaaata
       430        440        450        460        470        480
ccatcttcca tcaaaatatc tttggaggac gccaatgcat taagtaatta cactccgatt
       490        500        510        520        530        540
actccttcaa ttaagactac ccctgggttt caagaatctg ttttcactcc aattacatta
       550        560        570        580        590        600
caaattgaat atgaaatcag aaacccaaag tcgggtatta aattcgatac tgtgtatgct
       610        620        630        640        650        660
gacaagccct ggttatggaa cgtttacact tcaaatggtg agatttgcag ttctgcatca
       670        680        690        700        710        720
tattgggtcc catgtgtcga tttgcttgat gaaaaatcta catgggagtt agaattcagc
       730        740        750        760        770        780
gtaccgagat tggttaaaaa tataggtact tcgaaattaa tcggacaaaa tggagaagag
       790        800        810        820        830        840
agtgaaaaag agaaggagga tacgcctgag cacgatgaag aggaagaggg gaagccggca
       850        860        870        880        890        900
agagttatca aagacgaaga taaggattct aacttgaaaa atgacgaaga aggcaaaaat
       910        920        930        940        950        960
agtaaaagca aagatgcaca agataatgat gaagaagaag aggaaggcga aagtgacgaa
       970        980        990       1000       1010       1020
gaggaagagg aaggggaaga ggaaaggcgg aatattgagg aaagcaacaa tccgagtttg
      1030       1040       1050       1060       1070       1080
agggatgtga ttgtgtgttg ttcagaatat tcaaatatta aagaacttcc gcacccgatt
      1090       1100       1110       1120       1130       1140
gatttgacga aaaaaaaatg catatttcag ataattaatc ctgtggctcc acatcacatt
      1150       1160       1170       1180       1190       1200
ggttgggcta taggcgcctt taattcatgg tctttacctt tgatatcacc tccaagtgtt
      1210       1220       1230       1240       1250       1260
gatgccgagg acgaagtaga ggaagacaag ttgagagaga atgttgtgga caatgttaac
      1270       1280       1290       1300       1310       1320
gatactatgg atgacgacat tggttcggat attataccca ttcaaatttt cacacttccg
      1330       1340       1350       1360       1370       1380
acgcaggaaa cagatgagtt aacagttata aattcgacag ttgtctgcca aaaaattata
      1390       1400       1410       1420       1430       1440
gatttctact cgaaagaatt tgggtcttat cctttcactt gttactctat ggtgttttta
      1450       1460       1470       1480       1490       1500
cctaccgcac cttctaagca tatggatttt gcagcattag gcatttgtaa taccagatta
      1510       1520       1530       1540       1550       1560
ttgtaccctc tagaagttat tgataaagca ttcagtacta cgaatgagtt agcatgggca
      1570       1580       1590       1600       1610       1620
cttgctaacc aatggtcttg tgtgaatata actcctttag atatgaacga ctactggtgc
      1630       1640       1650       1660       1670       1680
tgtcttggta ttgctggtta tatggtgttt caggtaacca aaaaattaat gggtaataac
      1690       1700       1710       1720       1730       1740
acgtataaat atcaattaaa gcgtaatagt gaggcgattg tggaacaaga cttcgagaaa
      1750       1760       1770       1780       1790       1800
ccgcctattg ggagcacttt taccggcagt tctaggccaa tatcttggtc ttctaaagat
      1810       1820       1830       1840       1850       1860
ttgtccttta tacaattgaa ggcaccgatg atactacaca tacttgacag aaggatgact
      1870       1880       1890       1900       1910       1920
aaaacagaac gatctttcgg tatgtctcga gtattaccta aaattttcct tcaagctatg
      1930       1940       1950       1960       1970       1980
tctggtgatt taccgaataa ttcgttgact tcatcgcatt ttcaacatgt ttgcgaaaga
      1990       2000       2010       2020       2030       2040
gttaataaaa gtaaattaga gaattttttc aacgaatggg tatatgggtc tggggtaccc
      2050       2060       2070       2080       2090       2100
atattacgtg tcacccaaag atttaatagg aagaggatgg ttatagaact gggtataagg
      2110       2120       2130       2140       2150       2160
caagttcaag atgaagaact tggccacgaa aaagtggtag gggaggaagg atttttcaaa
      2170       2180       2190       2200       2210       2220
agtgcactag accacttaga acatccagat ttgaaccgaa ccgaatgctt cacgggctcg
      2230       2240       2250       2260       2270       2280
atgactataa ggatccatga acacgatggt actccgtatg agcatattgt ggaaatcaaa
      2290       2300       2310       2320       2330       2340
gatacattca caaaaataga tattcagtac aatacaaagt acagaagatt aaggaaaaga
      2350       2360       2370       2380       2390       2400
ggtggtggtg caaatgatga aaatggtgtt gaaaacaata atgaggagaa gcctattgtt
      2410       2420       2430       2440       2450       2460
gtggatgtga attgtctagg aaatgtatac atgtcgcccg aagagtgttc ccgattcagt
      2470       2480       2490       2500       2510       2520
ttgacggaat ttaatcgtac gtctgagagt aatgaattgc ttaagcaaaa cgaagcattt
      2530       2540       2550       2560       2570       2580
gagtggatac gcatagactc tgatctggaa tggatttgcc aaatgcacat taatcagccg
      2590       2600       2610       2620       2630       2640
gattacatgt tttcttctca gttgagacaa gatggggaca tagaggccca actagaagcc
      2650       2660       2670       2680       2690       2700
atacgatatt atgaggacgt cgttgttaat ggtggtgtga aatcacttgt ttattcaagt
      2710       2720       2730       2740       2750       2760
attttgttta gaacggcgat cgacgagcgt tacttttttg gcataagact cgcggcgtgc
      2770       2780       2790       2800       2810       2820
gaagcgctta gtaaatacgt atatgatccg gattttactg gcggtgttaa gcatttaatt
      2830       2840       2850       2860       2870       2880
cagatttttc agattttgtt ttgcctagaa gactctaata ttccaaagag taataacttt
      2890       2900       2910       2920       2930       2940
gagaatccta agttgtattt cttacagtgt aatattccca aatatttggc taaagtgaaa
      2950       2960       2970       2980       2990       3000
aatgaaaatg gtaaatgtcc aaaattggtg aagcaatttt tactggatat tcttgtttat
      3010       3020       3030       3040       3050       3060
aatgagaatg gtgaaaataa atacagtgat gatgcgtacg tccgcagctt gattgaaaat
      3070       3080       3090       3100       3110       3120
gttgttaaag ttgctttaaa tgagtataaa gataaagcat atatggaaaa agttaagact
      3130       3140       3150       3160       3170       3180
cagttattga ggtacgaaaa tttggtgaat tggctttcat catacgagtc tttgattaag
      3190       3200       3210       3220       3230       3240
actactatca tgtatgctaa gtacaaattg cataaagtgg gtgcttatga ctttacggaa
      3250       3260       3270       3280       3290       3300
ttgacaggaa tgataatgca tacattaaca ttaggtataa ataacggaga tatttccagg
      3310       3320       3330       3340       3350       3360
gaaagctttc agaatgagtt tttaatggtt ttgaaaatca tgcttttaga aggtggttta
      3370       3380       3390       3400       3410       3420
aaaaacaagg atgcccttgt tttgtttact gaaatacttt gcttccatga ggattcttat
      3430       3440       3450       3460       3470       3480
attagggata aaagtgttga tgtgctttct gaatgtgtaa atctagttgt tatggatggt
      3490       3500       3510       3520       3530       3540
agtttggata ccataagtga cgatattaag tcctccgtcc aatctgtgca caatgaagtt
      3550       3560       3570       3580       3590       3600
aaaaatataa aaagtgagga tgatattgag ttgtttttaa gtggtcatta cgtcgatgat
      3610       3620       3630       3640       3650       3660
atgaaaataa aaatagaaaa gattggccgt caaaatatta gtgggttaat acaaatatgc
      3670       3680       3690       3700       3710       3720
cgagatatgt ttaaagggta tagccctttg aagatattac tctgggatgt tttgaattta
      3730       3740       3750       3760       3770       3780
cctgttctta gcttgtacca gaggaagcaa atacatgatc ttgttagggt gatgtacacc
      3790       3800       3810       3820       3830       3840
ctaatcaaca gttttgtagt tagattggaa acaccaaggg agagaagact tgtggcgaag
      3850       3860       3870       3880       3890       3900
atgaatagta atgaagaagg taaacttgat attgttataa agcgtgaaag tatcctaaaa
      3910       3920       3930       3940       3950       3960
gtacatatta aaaaggaagt aacctctact gtggaggcac ccaagaaggc gaataagata
      3970       3980       3990       4000       4010       4020
aagataagtt tgaaaggtga taaacctgtt agaaaagtgg aaaaacaaat tgtgaagccg
      4030       4040       4050       4060       4070       4080
aaggtaacta gcaaacaaag gaaagtcaaa agtcatgtga accgcatggg cagtttacct
      4090       4100       4110       4120       4130       4140
ttacggtttg ttaagatcca acaacaacct agagtaatgg tgcatttgtc atccgtcccg
      4150       4160       4170       4180       4190       4200
tatagccaat tcgttcaaat tacaaaagtc acatcaagat cgtttatggt taagataaga
      4210       4220
acaaagaatg atgctaagaa ttga   

Last modification date: Oct. 2, 2011