Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]

FULL NAME: Cyclin-dependent kinase D-1


STRUCTURE SIMILARITY:
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Contains 1 protein kinase domain.


CATALYTIC ACTIVITY:
ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.


POST-TRANSLATIONAL MODIFICATION:
Autophosphorylated.


RELATED PATHWAY(S):
nucleotide excision repair (NER)
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MEQPKKVADR YLKREVLGQG TYGVVFKATD TKNGETVAIK KIRLGKEKEG VNVTALREIK
        70         80         90        100        110        120
LLKELKHPHI IELIDAFPHK ENLHIVFEFM ETDLEAVIRD RNLYLSPGDV KSYLQMILKG
       130        140        150        160        170        180
LEYCHGKWVL HRDMKPNNLL IGPNGQLKLA DFGLARIFGS PGRKFTHQVF ARWYRAPELL
       190        200        210        220        230        240
FGAKQYDGAV DVWAAGCIFA ELLLRRPFLQ GNSDIDQLSK IFAAFGTPKA DQWPDMICLP
       250        260        270        280        290        300
DYVEYQFVPA PSLRSLLPTV SEDALDLLSK MFTYDPKSRI SIQQALKHRY FTSAPSPTDP
       310        320        330        340        350        360
LKLPRPVSKQ DAKSSDSKLE AIKVLSPAHK FRRVMPDRGK SGNGFKDQSV DVMRQASHDG
       370        380        390
QAPMSLDFTI LAERPPNRPT ITSADRSHLK RKLDLEFL  

Encoded by CDKD1;1 gene


OTHER NAME(S):
AT;CDKD;1
CAK3AT
CDKD1;1
CYCLIN-DEPENDENT KINASE D1
cyclin-dependent kinase D1;1
F25P22.11
F25P22_11


DESCRIPTION:
cyclin dependent kinase activator CDKD;1. Nuclear localization. Involved in cell cycle regulation and cell differentiation.


Nucleic acid sequence

        10         20         30         40         50         60
atggaacagc cgaagaaagt tgctgatagg tatctaaagc gagaggttct tggtcaaggt
        70         80         90        100        110        120
acttatggag tcgtcttcaa agctactgat acaaagaatg gagaaactgt agcgatcaag
       130        140        150        160        170        180
aaaataagac ttggtaaaga gaaagaaggt gtgaatgtaa cagctcttag agaaatcaaa
       190        200        210        220        230        240
ttacttaaag agcttaagca tccacatata attgagttga ttgatgcgtt tcctcacaag
       250        260        270        280        290        300
gagaatttgc acatcgtgtt tgagttcatg gagactgatc tcgaagcagt tatccgagat
       310        320        330        340        350        360
cgtaatctct atctttcgcc tggtgatgtc aaatcttacc tccaaatgat attgaaaggt
       370        380        390        400        410        420
cttgaatatt gccatggcaa atgggttctg cacagagata tgaagccaaa caacttgttg
       430        440        450        460        470        480
ataggaccca atggacagct gaaacttgca gattttgggt tagcacgtat atttggtagc
       490        500        510        520        530        540
ccaggtcgta agtttaccca ccaggtgttt gctagatggt atagagcacc tgaacttttg
       550        560        570        580        590        600
tttggtgcaa aacaatatga tggtgcagtt gatgtttggg ctgctggctg catttttgct
       610        620        630        640        650        660
gaacttctat tacgcagacc atttcttcag ggaaacagtg atattgatca attaagcaaa
       670        680        690        700        710        720
atctttgctg cctttgggac tccaaaagca gatcagtggc ctgacatgat ctgccttcct
       730        740        750        760        770        780
gattatgtag agtatcaatt tgtccctgct ccttctttac gttctttact cccaacggtt
       790        800        810        820        830        840
agtgaggatg ctttagattt gttgtcaaag atgttcacct atgaccccaa gtctagaata
       850        860        870        880        890        900
tcgattcagc aggctctaaa acacaggtac ttcacatctg caccttcacc tactgaccct
       910        920        930        940        950        960
ttaaagctcc caagaccagt ttccaagcaa gatgctaagt catctgatag taaacttgaa
       970        980        990       1000       1010       1020
gccattaaag tgctgtcacc agcacataag tttagaagag tgatgcctga ccgaggaaag
      1030       1040       1050       1060       1070       1080
tctggtaatg gtttcaagga ccagagtgtt gatgtcatga gacaagctag ccatgatgga
      1090       1100       1110       1120       1130       1140
caagcaccaa tgtctttaga tttcaccatc ttagctgagc ggccaccaaa ccgaccaacc
      1150       1160       1170       1180       1190
atcaccagtg cagatagatc tcatctgaag aggaaacttg atctcgagtt cctatag

Last modification date: Oct. 2, 2011