Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: Probable DNA repair helicase ercc3


DESCRIPTION:
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA (By similarity).

STRUCTURE SIMILARITY:
Contains 1 helicase C-terminal domain.
Contains 1 helicase ATP-binding domain.
Belongs to the helicase family. RAD25/XPB subfamily.


CATALYTIC ACTIVITY:
ATP + H(2)O = ADP + phosphate.


RELATED PATHWAY(S):
nucleotide excision repair (NER)
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MSLKRKNNAR EGTPDEDLEE YSDYSDVDNY GEEDDDSYKP APRIRINNNK TKAQTTTNSN
        70         80         90        100        110        120
EARQSGISAM FGQNDFSNLL GLKLDHTARP LWINPIDGRI ILEAFSPLAE QAIDFLVTIS
       130        140        150        160        170        180
EPVSRPAFIH EYRITAYSLY AAVSVGLKTE DIIAVLDRLS KTPIPPSIVD FIRACTVSYG
       190        200        210        220        230        240
KVKLVLKKNR YFIESGDASV LRLLLRDPVI GPLRIDYSTQ SSKQKSSKPS NEDNVEDKKD
       250        260        270        280        290        300
ITNDSSKETA EKSSSDELFS AVVGLQEEED DEDAVHLFEI KHSSVETIKK RCAEIDYPLL
       310        320        330        340        350        360
EEYDFRNDNI NPDLPIDLKP STQIRPYQEK SLSKMFGNGR ARSGIIVLPC GAGKTLVGIT
       370        380        390        400        410        420
AACTIKKSVI VLCTSSVSVM QWRQQFLQWS NIKPDHIAVF TADHKERFHS EAGVVVSTYS
       430        440        450        460        470        480
MVANTRNRSY DSQKMMDFLT GREWGFILLD EVHVVPAAMF RRVVTTIAAH TKLGLTATLV
       490        500        510        520        530        540
REDDKIDDLN FLIGPKMYEA NWMDLAQKGH IAKVQCAEVW CAMTTEFYNE YLRENSRKRM
       550        560        570        580        590        600
LLYIMNPKKF QACQFLIDYH EKRGDKIIVF SDNVYALRAY AIKLGKYFIY GGTPQQERMR
       610        620        630        640        650        660
ILENFQYNEL VNTIFLSKVG DTSIDLPEAT CLIQISSHYG SRRQEAQRLG RILRAKRRND
       670        680        690        700        710        720
EGFNAFFYSL VSKDTQEMYY SSKRQAFLID QGYAFKVITN LKGMENLPNL AYASKAERLE
       730        740        750        760        770        780
LLQEVLLQNE EAADLDDGED TSFGSRSLSR APAKAKRSSG SLSTLAGADN MAYVEYNKSA
       790        800
NKQLKKDSKE HHALFRKHLY TKRR   

Encoded by ptr8 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgagcctaa agagaaaaaa taatgcaagg gaagggacac ctgacgagga tttagaagaa
        70         80         90        100        110        120
tatagcgatt acagcgatgt tgacaattac ggtgaagagg atgatgattc ttacaagcct
       130        140        150        160        170        180
gcacccagga ttcgtataaa caacaataaa actaaagcac aaaccacgac taatagcaat
       190        200        210        220        230        240
gaagcccgcc aatctgggat ttctgctatg tttggccaaa acgatttttc taatttacta
       250        260        270        280        290        300
ggtttaaaat tggatcatac ggctaggcca ctttggatta atccaattga tggtagaatt
       310        320        330        340        350        360
atccttgaag cattcagccc attggctgag caagctatcg acttcttggt aacaatttca
       370        380        390        400        410        420
gagccagttt ctcgacccgc tttcattcat gagtatagaa ttactgcata ttcactttat
       430        440        450        460        470        480
gctgctgtta gcgttgggtt aaaaactgaa gatataatag cagtccttga tagactttca
       490        500        510        520        530        540
aaaaccccaa ttcctccttc tatcgtagac tttatccgcg cttgtactgt ctcttacggt
       550        560        570        580        590        600
aaggtcaaac tggtcttgaa gaaaaacaga tattttattg aaagtggaga tgcaagtgtt
       610        620        630        640        650        660
ttacgactgt tattaagaga tcctgtcata ggccctcttc gaatcgatta ttctacccag
       670        680        690        700        710        720
tctagcaagc agaagtcttc aaagccttcc aatgaagata atgtggaaga caaaaaagat
       730        740        750        760        770        780
atcaccaatg attcctcaaa agaaactgct gagaaaagtt catctgatga actgttttcg
       790        800        810        820        830        840
gcagtagtag gcttacagga agaggaagat gatgaagatg ccgttcatct tttcgaaatt
       850        860        870        880        890        900
aagcactctt cagtggaaac tatcaagaag agatgtgcag agattgatta tcccttattg
       910        920        930        940        950        960
gaagagtacg attttcgtaa tgacaacatc aatccagatc ttcctataga ccttaagcca
       970        980        990       1000       1010       1020
agcactcaaa ttcgtccata ccaagaaaag agtcttagta aaatgtttgg aaatggtaga
      1030       1040       1050       1060       1070       1080
gctcgaagtg gaattattgt attaccatgt ggagctggta aaaccttggt tggtatcaca
      1090       1100       1110       1120       1130       1140
gcggcttgta ctatcaaaaa atcagtaatc gtgctttgca ccagttctgt ttcggtaatg
      1150       1160       1170       1180       1190       1200
caatggcgtc aacaattttt acagtggagc aacatcaagc ctgatcacat tgcggttttt
      1210       1220       1230       1240       1250       1260
actgctgatc acaaagaacg gtttcacagc gaagcaggtg tggttgtctc cacgtactca
      1270       1280       1290       1300       1310       1320
atggttgcca ataccaggaa tagatcctat gattctcaaa aaatgatgga ttttcttacg
      1330       1340       1350       1360       1370       1380
ggacgtgaat gggggtttat cctattagac gaagtacatg tggttcctgc tgccatgttt
      1390       1400       1410       1420       1430       1440
cggcgagttg tcaccacaat tgccgctcac acaaagcttg ggttaactgc tacgttagtt
      1450       1460       1470       1480       1490       1500
cgtgaggatg ataaaattga tgatttaaat tttttgattg ggcctaaaat gtacgaagca
      1510       1520       1530       1540       1550       1560
aattggatgg atttggcaca aaaaggtcac atcgctaagg ttcaatgcgc cgaagtttgg
      1570       1580       1590       1600       1610       1620
tgcgcgatga ccactgagtt ttataatgaa tatcttcgag aaaactcccg aaaaagaatg
      1630       1640       1650       1660       1670       1680
ctactttata tcatgaatcc taaaaaattt caggcttgtc aattcctcat cgattatcac
      1690       1700       1710       1720       1730       1740
gaaaaacgtg gtgataaaat tatcgttttt tcagacaatg tctatgcttt gcgtgcttat
      1750       1760       1770       1780       1790       1800
gcaataaaat taggcaaata ttttatttat ggtggaactc cacagcagga aagaatgagg
      1810       1820       1830       1840       1850       1860
attttggaaa atttccagta taatgaactt gtaaatacca ttttcctttc taaagttggt
      1870       1880       1890       1900       1910       1920
gatacgtcta ttgatcttcc tgaagcaacc tgtttgattc agatttcttc tcattatggt
      1930       1940       1950       1960       1970       1980
tctaggcgtc aagaagctca acgtttgggg cgtattcttc gtgccaagcg acgaaatgat
      1990       2000       2010       2020       2030       2040
gaaggcttta acgcattttt ctatagcttg gtatctaaag acactcagga aatgtattat
      2050       2060       2070       2080       2090       2100
tccagtaaac ggcaagcatt tttaattgac caaggctatg cttttaaagt catcactaat
      2110       2120       2130       2140       2150       2160
ttaaagggta tggagaactt gccaaatttg gcttacgcct ccaaagcgga gagacttgag
      2170       2180       2190       2200       2210       2220
cttttgcagg aagtattgct acaaaatgaa gaagcagctg atttggatga cggtgaggat
      2230       2240       2250       2260       2270       2280
actagctttg gatccagaag tctctctaga gcaccggcga aagctaaacg ttctagtggt
      2290       2300       2310       2320       2330       2340
tctttaagta cattggctgg tgccgacaat atggcatacg tggaatataa caagagtgct
      2350       2360       2370       2380       2390       2400
aataaacagc tgaaaaagga cagtaaagaa catcatgcct tatttcggaa gcacctgtat
      2410
actaaacgtc gctag    

Last modification date: Oct. 2, 2011