Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: UV excision repair protein rhp23


DESCRIPTION:
Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.
Involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA.

STRUCTURE SIMILARITY:
Contains 2 UBA domains.
Contains 1 ubiquitin-like domain.


RELATED PATHWAY(S):
nucleotide excision repair (NER)


Amino acids sequence

        10         20         30         40         50         60
MNLTFKNLQQ QKFVISDVSA DTKISELKEK IQTQQNYEVE RQKLIYSGRI LADDKTVGEY
        70         80         90        100        110        120
NIKEQDFIVC MVSRPKTSTS TPKSAASPAP NPPASVPEKK VEAPSSTVAE STSTTQTVAA
       130        140        150        160        170        180
AAPSNPDTTA TSEAPIDANT LAVGAQRNVA VENMVEMGYE RSEVERAMRA AFNNPDRAVE
       190        200        210        220        230        240
YLLTGIPEDI LNRQREESAA ALAAQQQQSE ALAPTSTGQP ANLFEQAALS ENENQEQPSN
       250        260        270        280        290        300
TVGDDPLGFL RSIPQFQQLR QIVQQNPQML ETILQQIGQG DPALAQAITQ NPEAFLQLLA
       310        320        330        340        350        360
EGAEGESALP SGGIQIQITQ EESESIDRLC QLGFDRNIVI QAYLACDKNE ELAANYLFEH

GHESEDEP     

Encoded by rhp23 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgaatttga cattcaaaaa tctacagcag cagaaatttg ttatttctga tgtttctgca
        70         80         90        100        110        120
gataccaaaa tttcagaatt aaaagaaaaa attcaaacgc aacagaatta tgaagtcgaa
       130        140        150        160        170        180
cgtcaaaagt taatttactc aggtcgaatc cttgctgatg acaaaactgt tggcgaatac
       190        200        210        220        230        240
aatataaaag aacaggattt cattgtatgc atggtttcac gacccaaaac ttccacctct
       250        260        270        280        290        300
actccgaaat cagctgccag tcctgccccc aatcctccgg cttccgtacc tgaaaagaaa
       310        320        330        340        350        360
gttgaagctc cttcttctac cgtggcggaa tctacctcta ctacacaaac tgttgctgct
       370        380        390        400        410        420
gctgcccctt caaacccaga tactactgcc actagtgaag caccaataga cgccaacaca
       430        440        450        460        470        480
ttggcagttg gtgctcaacg aaatgttgct gtcgaaaata tggtagaaat gggatacgaa
       490        500        510        520        530        540
cgcagcgaag ttgaaagagc catgcgtgcc gcttttaaca accctgatcg ggcagtggaa
       550        560        570        580        590        600
tacttattaa ctggtattcc cgaagacatt ctcaatcgac agagagaaga gagtgctgca
       610        620        630        640        650        660
gcccttgctg ctcagcaaca gcaaagcgaa gcccttgctc ctacttccac tggccagcca
       670        680        690        700        710        720
gcgaatcttt ttgaacaagc tgctttatca gaaaatgaaa atcaagaaca accttctaat
       730        740        750        760        770        780
accgttggtg atgaccctct aggcttcctt cgtagcattc ctcaatttca acagctaaga
       790        800        810        820        830        840
caaattgttc aacaaaatcc acagatgttg gaaactatat tgcaacaaat tgggcaggga
       850        860        870        880        890        900
gatcctgcat tggctcaagc tattacgcaa aatcctgaag catttttgca attattggcg
       910        920        930        940        950        960
gagggtgccg aaggcgagtc tgccttacct tctggtggaa ttcagattca aattactcaa
       970        980        990       1000       1010       1020
gaagaatctg agagtattga tagattatgt caacttggct tcgacagaaa cattgtaatt
      1030       1040       1050       1060       1070       1080
caggcttatt tagcttgtga taaaaatgaa gagcttgctg ctaattacct tttcgagcat
      1090       1100
ggacatgaat ctgaggatga accttaa   

Last modification date: Oct. 2, 2011