Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: DNA repair protein RAD10


DESCRIPTION:
Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD1 forms an endonuclease that specifically degrades single-stranded DNA.

STRUCTURE SIMILARITY:
Belongs to the ERCC1/RAD10/SWI10 family.


RELATED PATHWAY(S):
Fanconi anemia (FA) pathway
nucleotide excision repair (NER)


Amino acids sequence

        10         20         30         40         50         60
MNNTDPTSFE SILAGVAKLR KEKSGADTTG SQSLEIDASK LQQQEPQTSR RINSNQVINA
        70         80         90        100        110        120
FNQQKPEEWT DSKATDDYNR KRPFRSTRPG KTVLVNTTQK ENPLLNHLKS TNWRYVSSTG
       130        140        150        160        170        180
INMIYYDYLV RGRSVLFLTL TYHKLYVDYI SRRMQPLSRN ENNILIFIVD DNNSEDTLND
       190        200        210
ITKLCMFNGF TLLLAFNFEQ AAKYIEYLNL   

Encoded by RAD10 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgaacaata ctgatcctac ttcatttgaa agtatattgg ctggtgtggc caaattgaga
        70         80         90        100        110        120
aaggaaaaga gtggtgcaga tactactgga tctcaatcgt tagaaataga tgcatcaaaa
       130        140        150        160        170        180
ctccagcagc aggaaccgca aacatcaaga cgcataaatt caaaccaggt cataaacgcc
       190        200        210        220        230        240
ttcaatcagc aaaaaccgga agaatggacc gactcaaagg ctacagatga ctataatcga
       250        260        270        280        290        300
aagagaccct tcaggagtac tcgaccggga aaaactgtac tagtgaacac tacccaaaaa
       310        320        330        340        350        360
gaaaatccac tcctgaacca cttaaagagc accaattgga gatatgtatc ttcaacagga
       370        380        390        400        410        420
attaatatga tatactacga ctatctagtt cgtggaagaa gtgtactgtt cttaactttg
       430        440        450        460        470        480
acttatcaca aattatatgt cgattatatc tctaggagaa tgcagccctt atctagaaac
       490        500        510        520        530        540
gaaaataata tactgatatt catagtagac gataacaact ctgaagatac ccttaatgac
       550        560        570        580        590        600
attacaaaac tatgtatgtt caacggattt actctacttt tagcatttaa ttttgaacaa
       610        620        630
gctgcaaaat atattgaata tttgaattta tga  

Last modification date: Oct. 2, 2011