Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: RNA polymerase II transcription factor B subunit 5


DESCRIPTION:
Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro. TFB5 is required for stable recruitment of TFIIH to a promoter, but not for stability of TFIIH subunits.

STRUCTURE SIMILARITY:
Belongs to the TFB5 family.


RELATED PATHWAY(S):
nucleotide excision repair (NER)
transcription factors


Amino acids sequence

        10         20         30         40         50         60
MARARKGALV QCDPSIKALI LQIDAKMSDI VLEELDDTHL LVNPSKVEFV KHELNRLLSK
        70
NIYNPMDEEE NQ    

Encoded by TFB5 gene


Nucleic acid sequence

        10         20         30         40         50         60
atggctagag caagaaaggg tgcactggtt caatgtgatc catccatcaa ggcgctcata
        70         80         90        100        110        120
ttacaaattg acgccaagat gagtgatata gtactagagg agttggatga cacccatctt
       130        140        150        160        170        180
ttagtaaatc cctcgaaagt cgaatttgtt aagcatgagc taaataggct attatctaag
       190        200        210
aatatatata atcctatgga tgaagaagaa aatcagtaa  

Last modification date: Oct. 2, 2011