Mus musculus L. (mouse) [MMU]

FULL NAME: ATR-interacting protein


DESCRIPTION:
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein (By similarity).

STRUCTURE SIMILARITY:
Belongs to the ATRIP family.


POST-TRANSLATIONAL MODIFICATION:
Phosphorylated by ATR (By similarity).


RELATED PATHWAY(S):
Fanconi anemia (FA) pathway
DNA damage response (DDR)


Amino acids sequence

        10         20         30         40         50         60
MAGTPAPNSH RKQSGGLEPF PGLSRSIENP PSKRARSFSE TTVPDPEDPF GEHAEFTADD
        70         80         90        100        110        120
LEELDILASQ ALSQCPVAPR NLSSAHKVRR LDGLPNSPIR KSREDIPVKD NFELEVLQIQ
       130        140        150        160        170        180
YKELKEKLKA MEEEILIKNG EIKILRDSLR QTESVLEEQK RSHFLLEQEK TQALSEKEKE
       190        200        210        220        230        240
FSRKLQSLQS ELQFKDAEMN ELRTKSQSNG RTNKPAAPSV SHVSPRKGSS VVLKSEACSP
       250        260        270        280        290        300
HVGKTTFPTK ESFSANTPLF HPCQTEAGHR FLVGQEVSDN KNHSLGGSLM KQDVQQRILA
       310        320        330        340        350        360
DGWMQRKDAQ GSILINLLLK QPLVPGSSLG LCHLLSSCPE VPTGTLLQPP GLSTLPGTSG
       370        380        390        400        410        420
LRTISSSDGP FSPSALREAQ NLAFTGLNLV ARTESSHDGD MAGRRVFPLH QLPGAVHLLP
       430        440        450        460        470        480
LVQFFVGLHC QALQDLAPAK KSGVPGDSAT HTSCMSSGVE ASPEDSIHGL ESFSVASLSV
       490        500        510        520        530        540
LQNLVCHSGA VVCLLLSGMG TEAAAREGNL VQTCADTTSA SREDAHDQDQ HPLLKMLLQL
       550        560        570        580        590        600
MASSSAASGH FQASVLGLCL KVLVKLAENA SSDLLPRFSC VFPVLPQCLG SALPLPCVLL
       610        620        630        640        650        660
AVELLSVLLD HDSLAWQLCS HPEGCLLLRL YMYITSRPDR TASETQWLQL EQEVVWLLAK
       670        680        690        700        710        720
LSVQSPAPAG IGSDCHCNVE AVRALTVMLH RQWLTVRRAG GPRTHQQKQT IRCLRDTVLL
       730        740        750        760        770        780
LHSLSQKDKL FTVHCVEVLH QYDQVMPGVS MLIRALPDVT DCEEAALDDL CAAETDLEDS

EMDCN     

Encoded by Atrip gene

FULL NAME: ATR interacting protein


OTHER NAME(S):
6620401K05Rik
MGC90531


Nucleic acid sequence

        10         20         30         40         50         60
atggccggga cccccgcacc gaacagccac aggaaacaga gtggcggcct ggagcctttc
        70         80         90        100        110        120
cccggtctgt ctcgatccat tgagaaccct ccgagcaagc gggcccggag cttctctgag
       130        140        150        160        170        180
accacagtcc cggaccccga agacccattc ggtgagcacg cggaatttac tgcggacgac
       190        200        210        220        230        240
ctagaggaac tcgacatcct cgcgtcacag gccctgagcc agtgtcccgt cgcgcctcgg
       250        260        270        280        290        300
aacctgtcca gtgctcataa ggtccgccga ttagatgggt taccaaatag tcctataagg
       310        320        330        340        350        360
aaaagcagag aagatattcc agttaaagat aattttgaat tagaagtact tcagatacaa
       370        380        390        400        410        420
tacaaagaac ttaaagaaaa gctgaaagca atggaagaag aaatcctaat taagaatgga
       430        440        450        460        470        480
gaaattaaaa ttttgcgtga ctctctgcgt cagacagaat ccgttctaga agaacagaaa
       490        500        510        520        530        540
agatcacatt tccttcttga gcaagaaaag actcaagcac tcagtgaaaa ggaaaaggaa
       550        560        570        580        590        600
ttctccagaa agctccaatc actgcagtct gaactgcagt ttaaagacgc agaaatgaat
       610        620        630        640        650        660
gagttaagga caaagtctca gagcaacgga cgaacaaata agccagccgc tccctccgtc
       670        680        690        700        710        720
tcccacgtca gtcctaggaa aggctcttct gtggttctca agtcagaagc atgttctcca
       730        740        750        760        770        780
catgttggaa aaacaacttt ccctacaaaa gaatctttta gtgctaacac gcctctcttc
       790        800        810        820        830        840
cacccctgtc agactgaggc aggacacaga tttctggtgg gccaagaggt ttcagataat
       850        860        870        880        890        900
aaaaaccaca gtctgggagg tagcctcatg aagcaagatg tgcagcagag aattctggct
       910        920        930        940        950        960
gatggctgga tgcagagaaa agatgctcaa ggttctattt tgataaactt gctcctgaag
       970        980        990       1000       1010       1020
caacctttgg tgccagggtc atctctaggt ctttgtcacc ttctgagcag ttgtcctgag
      1030       1040       1050       1060       1070       1080
gttcctactg gcaccctctt gcagccacca gggctcagta ctttgcctgg gacttcaggc
      1090       1100       1110       1120       1130       1140
ctcaggacca tcagttcttc tgatgggcca ttttccccct ctgccctgag agaagcacag
      1150       1160       1170       1180       1190       1200
aacttggcat tcactggatt aaatctggtt gccaggactg agagctcaca tgatggagac
      1210       1220       1230       1240       1250       1260
atggcaggca gaagagtctt cccgctccac cagcttcctg gagctgtgca tctccttcct
      1270       1280       1290       1300       1310       1320
cttgtgcagt ttttcgtcgg cttacactgc caggctctgc aagatttagc cccagctaag
      1330       1340       1350       1360       1370       1380
aagagtgggg tgcctgggga ctctgcgaca catacctcct gcatgagctc tggggtcgag
      1390       1400       1410       1420       1430       1440
gctagcccag aggactccat tcatggcttg gagagctttt ctgtggcatc actcagcgtc
      1450       1460       1470       1480       1490       1500
cttcagaacc tggtgtgcca cagtggggca gttgtctgcc tgttactgtc aggcatgggg
      1510       1520       1530       1540       1550       1560
acagaagctg ccgccaggga aggaaacttg gtccagactt gtgcagatac aacctcagcc
      1570       1580       1590       1600       1610       1620
tccagggagg atgctcatga ccaagaccag cacccactgc taaagatgct tcttcagctg
      1630       1640       1650       1660       1670       1680
atggcttcct cctctgcagc atcaggtcat tttcaagcca gtgtcctggg cctgtgcctc
      1690       1700       1710       1720       1730       1740
aaagttttgg tgaaattagc agaaaacgct tcctctgatt tgttgcccag gttctcctgt
      1750       1760       1770       1780       1790       1800
gtgttcccgg tgttgccaca gtgcctcggc tcagcgctgc cgctgccctg tgtgctcctg
      1810       1820       1830       1840       1850       1860
gctgttgagc tgctctctgt gctgctggac catgacagcc tagcatggca gctatgctcc
      1870       1880       1890       1900       1910       1920
cacccagaag gctgccttct cctgaggctg tacatgtaca tcacatcaag gcctgacaga
      1930       1940       1950       1960       1970       1980
acggcctcag agacacagtg gcttcagctg gaacaagagg tagtatggct cttggccaag
      1990       2000       2010       2020       2030       2040
ctgagtgtac agagccctgc ccccgctggc attggttctg actgtcactg caatgtagag
      2050       2060       2070       2080       2090       2100
gcagtcagag cgctcactgt gatgttgcac aggcaatggc tgacggtgcg gcgggcagga
      2110       2120       2130       2140       2150       2160
ggtccaagga cccaccagca gaagcagacg atacgctgtc tgcgggacac tgtgctgctg
      2170       2180       2190       2200       2210       2220
ctgcatagcc tatctcagaa ggacaagctc ttcactgtgc actgtgtcga ggtcctgcat
      2230       2240       2250       2260       2270       2280
cagtacgacc aggtgatgcc aggggtcagc atgctgattc gagcccttcc tgatgtgact
      2290       2300       2310       2320       2330       2340
gactgtgaag aggctgccct ggatgacctc tgtgctgcgg agactgattt ggaagactct
      2350
gagatggact gtaactga    

Last modification date: Oct. 2, 2011