Saccharomyces cerevisiae Meyen ex E.C. Hansen (budding yeast) [SCE]

FULL NAME: DNA base excision repair N-glycosylase 2


DESCRIPTION:
Excision repair N-glycosylase involved in the repair of DNA base damage in the nucleus. NTG2 can use dihydrothymine (poor substrate), urea, and uracil glycol are substrates.

MISCELLANEOUS:
Present with 125 molecules/cell in log phase SD medium.


STRUCTURE SIMILARITY:
Belongs to the Nth/MutY family.


RELATED PATHWAY(S):
base excision repair (BER)


Amino acids sequence

        10         20         30         40         50         60
MREESRSRKR KHIPVDIEEV EVRSKYFKKN ERTVELVKEN KINKDLQNYG GVNIDWIKAL
        70         80         90        100        110        120
KPIEYFEWIE SRTCDDPRTW GRPITKEEMI NDSGAKVPES FLPIYNRVRL MRSKVKTPVD
       130        140        150        160        170        180
AMGCSMIPVL VSNKCGIPSE KVDPKNFRLQ FLIGTMLSAQ TRDERMAQAA LNITEYCLNT
       190        200        210        220        230        240
LKIAEGITLD GLLKIDEPVL ANLIRCVSFY TRKANFIKRT AQLLVDNFDS DIPYDIEGIL
       250        260        270        280        290        300
SLPGVGPKMG YLTLQKGWGL IAGICVDVHV HRLCKMWNWV DPIKCKTAEH TRKELQVWLP
       310        320        330        340        350        360
HSLWYEINTV LVGFGQLICM ARGKRCDLCL ANDVCNARNE KLIESSKFHQ LEDKEDIEKV
       370        380
YSHWLDTVTN GITTERHKKK    

Encoded by NTG2 gene


OTHER NAME(S):
SCR2


Nucleic acid sequence

        10         20         30         40         50         60
atgagagagg aaagtaggtc taggaagaga aagcatattc ctgttgatat tgaagaggta
        70         80         90        100        110        120
gaagttcgat ctaagtattt caaaaagaat gagagaactg ttgagttagt aaaagaaaat
       130        140        150        160        170        180
aaaatcaata aagatttgca aaattacggc ggagtaaata ttgactggat caaggcactg
       190        200        210        220        230        240
aagccaatag agtattttga atggatcgaa tcaaggactt gtgatgatcc gagaacttgg
       250        260        270        280        290        300
ggacggccaa taactaaaga agaaatgatt aacgattctg gggcgaaagt tcctgagagt
       310        320        330        340        350        360
ttcttaccca tatataatcg ggtgagatta atgaggtcca aggttaaaac cccggtagat
       370        380        390        400        410        420
gctatgggat gtagcatgat tcctgtttta gtttctaata aatgtgggat acctagtgaa
       430        440        450        460        470        480
aaagtcgatc caaagaattt caggcttcaa tttcttattg gcactatgct ttctgctcaa
       490        500        510        520        530        540
acgagggacg aaaggatggc gcaagcggct ttgaatatca ccgaatactg cttaaacaca
       550        560        570        580        590        600
ttaaaaatag cagagggtat tacgctagat ggactgctta aaattgatga acctgtatta
       610        620        630        640        650        660
gcaaatctaa ttcgatgcgt tagcttctat accagaaaag ccaatttcat caaaagaacc
       670        680        690        700        710        720
gcacaattat tggtagacaa tttcgattca gatataccgt atgatataga gggaattctc
       730        740        750        760        770        780
tcgttacctg gagttggacc taaaatggga tatttaacac tgcaaaaagg ttgggggctg
       790        800        810        820        830        840
attgccggca tatgcgtcga tgttcatgtc cataggctgt gtaaaatgtg gaattgggta
       850        860        870        880        890        900
gaccctatta agtgtaagac tgccgagcat actagaaagg agttacaggt ttggctacct
       910        920        930        940        950        960
cactcactgt ggtacgaaat aaacaccgtt ttggttggat ttggtcaatt gatctgcatg
       970        980        990       1000       1010       1020
gccaggggta agaggtgtga tttatgtcta gcaaacgatg tctgcaatgc tcgcaatgag
      1030       1040       1050       1060       1070       1080
aagctaatcg aatcttccaa atttcatcaa ttggaggaca aagaagacat cgagaaagta
      1090       1100       1110       1120       1130       1140
tattcgcatt ggttggacac ggttacaaat ggaattacaa cagaaagaca caagaaaaaa

tag     

Last modification date: Oct. 2, 2011