Schizo-saccharomyces pombe Lindner (fission yeast) [SPO]

FULL NAME: DNA mismatch repair protein pms1


DESCRIPTION:
This protein is involved in the repair of mismatches in DNA.

STRUCTURE SIMILARITY:
Belongs to the DNA mismatch repair mutL/hexB family.


RELATED PATHWAY(S):
Fanconi anemia (FA) pathway
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MSTVKPIDAN TVHKICSGQV ITDVASAVKE LVENSLDSGA TTIEIRFKNY GINSIEVVDN
        70         80         90        100        110        120
GSGIDAGDYE SIGKKHFTSK ITDFEDLEAL QTFGFRGEAL SSLCAVGQVI ISTATQNEAP
       130        140        150        160        170        180
KGVQLNLDHE GSLKDKLTIP FQRGTSVMVN DLFCTLPVRR KLLEKNYKRE FSKAISLLQA
       190        200        210        220        230        240
YATISTNKRF MVYHQTKNSG KLLQLSTNSN KDMKLNIMNV FGTKVSSSLI PWNDGIIEGY
       250        260        270        280        290        300
ISRPHVGSTR ASNERQMLFI NRRLVNLPKI ARVIQEVFKP YSMAQSPFFA INLRITNGTI
       310        320        330        340        350        360
DINVSPDKKS VFLSEEDSII EFIKNSLQNL CESCGHAISC SRSQSIFSYS SQIPDSSGDS
       370        380        390        400        410        420
TDQELPQSIP ATESETSDDS SFSYKRSPCK RKLVEATAQP AISTSVAEGA SLAQVSKPLP
       430        440        450        460        470        480
ERLQKDSMRR SSPLNEKVTA SSERMKKKLA LFASSTDTSM QKTIDSSFPL KQPINKPSSN
       490        500        510        520        530        540
PNNLLLNDPS PASTPVAKTI NLNEIESVHN AESVSTLSSI PRTEQTSVAN RIPSKTAALQ
       550        560        570        580        590        600
KLKFFQSRPL DGLNKFSKKI NISLSGVQKD IVRSDALLKF SNKIGVVHDI SDENQEDHLN
       610        620        630        640        650        660
LTVHKADFLR MRVVGQFNRG FIVVVHGNNL FIIDQHASDE KFNYEHLKSN LVINSQDLVL
       670        680        690        700        710        720
PKRLDLAATE ETVLIDHIDL IRRKGFGVAI DLNQRVGNRC TLLSVPTSKN VIFDTSDLLE
       730        740        750        760        770        780
IISVLSEHPQ IDPFSSRLER MLASKACRSS VMIGRALTIS EMNTIVRHLA ELSKPWNCPH
       790
GRPTMRHLLR LKDI    

Encoded by pms1 gene


Nucleic acid sequence

        10         20         30         40         50         60
atgtcaacgg ttaaacctat cgacgccaat acagtacata aaatatgctc aggccaagtt
        70         80         90        100        110        120
attactgacg ttgcatcggc tgtcaaagag ttggttgaga actctttgga ttcaggagcg
       130        140        150        160        170        180
acaaccattg agattcgctt taagaattat ggtatcaatt ctattgaggt ggtggataat
       190        200        210        220        230        240
ggctcgggta tcgatgctgg tgactacgag agtataggaa aaaagcattt tacttcaaaa
       250        260        270        280        290        300
attactgatt ttgaagattt ggaagcctta cagaccttcg gatttcgtgg tgaagccctg
       310        320        330        340        350        360
agtagtctct gtgcagtagg acaagttatt atatcgacgg ctacacagaa tgaggcgcca
       370        380        390        400        410        420
aaaggcgtac agctcaatct tgatcatgaa ggttcattaa aagataaatt aacaattcct
       430        440        450        460        470        480
tttcaaagag gtacctctgt catggttaat gatttgtttt gtacacttcc tgttcgtcga
       490        500        510        520        530        540
aaacttttgg agaaaaacta taaacgggaa ttttcgaagg caatctcctt gttgcaggct
       550        560        570        580        590        600
tatgccacta tttctacaaa taagcgcttc atggtatatc atcaaactaa gaattctggc
       610        620        630        640        650        660
aagttgcttc agctttcaac aaattctaat aaggatatga agttgaacat catgaatgta
       670        680        690        700        710        720
tttggtacta aagtatcttc atcacttatt ccttggaatg atggaatcat agaaggttac
       730        740        750        760        770        780
atatcacgtc cgcacgttgg atcaactcgt gcgtcgaatg agaggcaaat gttgtttatt
       790        800        810        820        830        840
aaccggaggc ttgtaaattt gccaaaaata gcaagagtta ttcaagaggt atttaagccg
       850        860        870        880        890        900
tatagtatgg cacaatcccc gttttttgcc atcaatcttc gcatcacaaa tggaactatt
       910        920        930        940        950        960
gacatcaatg tatctccaga caaaaaatct gtatttttgt ctgaagagga ttccataatt
       970        980        990       1000       1010       1020
gaatttatta aaaactcctt gcaaaaccta tgtgaaagct gcggacatgc aatttcttgt
      1030       1040       1050       1060       1070       1080
tccagatcgc aatccatttt ttcatattcc tcgcaaattc ctgattcctc tggagacagt
      1090       1100       1110       1120       1130       1140
acagatcagg aattgcctca gtcaattcca gcaacagaat ccgaaacaag tgatgactca
      1150       1160       1170       1180       1190       1200
agtttttctt ataaacgctc accatgtaaa agaaagctcg tagaagctac tgctcaacca
      1210       1220       1230       1240       1250       1260
gcaatatcca ctagtgttgc agaaggagcg tcattagcac aagtatccaa acctttgcca
      1270       1280       1290       1300       1310       1320
gagcgtttgc aaaaggattc tatgagacga agtagcccat taaacgaaaa agttacggcc
      1330       1340       1350       1360       1370       1380
tcttccgaaa gaatgaagaa aaagcttgcc ctattcgctt ctagtactga tacttctatg
      1390       1400       1410       1420       1430       1440
cagaaaacaa tagactctag tttcccacta aagcaaccca tcaataaacc tagctcgaat
      1450       1460       1470       1480       1490       1500
cctaacaatt tgttactaaa tgatccaagt ccagcatcaa cacctgttgc taaaacaatt
      1510       1520       1530       1540       1550       1560
aatttaaacg agattgagtc ggtacacaac gcagaatcag tttccacact ctcgagcatt
      1570       1580       1590       1600       1610       1620
cctcgtactg agcaaaccag tgttgcgaac agaattccgt caaaaactgc agcgctacaa
      1630       1640       1650       1660       1670       1680
aagctcaaat tttttcaatc taggcccttg gatggtttaa acaagtttag taaaaaaata
      1690       1700       1710       1720       1730       1740
aatatatctt tgagtggagt gcaaaaagat attgttcgaa gcgatgcctt actgaaattt
      1750       1760       1770       1780       1790       1800
tcgaacaaga ttggcgtggt gcatgatatt tcagatgaaa atcaggaaga tcatttgaat
      1810       1820       1830       1840       1850       1860
ctaactgtac ataaagccga ttttttaaga atgagggttg ttggtcaatt caatagagga
      1870       1880       1890       1900       1910       1920
ttcatagtgg ttgttcatgg aaacaatttg tttataattg atcaacatgc cagcgatgaa
      1930       1940       1950       1960       1970       1980
aagttcaact atgaacatct caaaagtaat ttagttatca acagccaaga cttagtcctt
      1990       2000       2010       2020       2030       2040
ccaaaaagac tggatttagc tgctacagag gaaactgttt taattgacca tatagattta
      2050       2060       2070       2080       2090       2100
attcgaagaa aaggattcgg cgttgctata gatttaaatc agcgagttgg taatcgctgc
      2110       2120       2130       2140       2150       2160
actcttcttt cagttcccac gagtaagaat gtcatttttg acactagtga tttactagag
      2170       2180       2190       2200       2210       2220
atcatcagtg tgttgtctga gcacccacag atagacccat ttagtagtag gcttgagcga
      2230       2240       2250       2260       2270       2280
atgcttgctt caaaggcttg tagaagcagt gtcatgattg gtagggctct aactatatcc
      2290       2300       2310       2320       2330       2340
gaaatgaata caatagttag gcatcttgct gagttgagca agccttggaa ttgccctcat
      2350       2360       2370       2380
ggaaggccaa ctatgaggca tctccttcga ttaaaagata tataa 

Last modification date: Oct. 2, 2011