Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]


RELATED PATHWAY(S):
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MKTIKPLPEG VRHSMRSGII MFDMARVVEE LVFNSLDAGA TKVSIFVGVV SCSVKVVDDG
        70         80         90        100        110        120
SGVSRDDLVL LGERYATSKF HDFTNVETAS ETFGFRGEAL ASISDISLLE VRTKAIGRPN
       130        140        150        160        170        180
GYRKVMKGSK CLHLGIDDDR KDSGTTVTVR DLFYSQPVRR KYMQSSPKKV LESIKKCVFR
       190        200        210        220        230        240
IALVHSNVSF SVLDIESDEE LFQTNPSSSA FSLLMRDAGT EAVNSLCKVN VTDGMLNVSG
       250        260        270        280        290        300
FECADDWKPT DGQQTGRRNR LQSNPGYILC IACPRRLYEF SFEPSKTHVE FKKWGPVLAF
       310        320        330        340        350        360
IERITLANWK KDRILELFDG GADILAKGDR QDLIDDKIRL QNGSLFSILH FLDADWPEAM
       370        380        390        400        410        420
EPAKKKLKRS NDHAPCSSLL FPSADFKQDG DYFSPRKDVW SPECEVELKI QNPKEQGTVA
       430        440        450        460        470        480
GFESRTDSLL QSRDIEMQTN EDFPQVTDLL ETSLVADSKC RKQFLTRCQI TTPVNINHDF
       490        500        510        520        530        540
MKDSDVLNFQ FQGLKDELDV SNCIGKHLLR GCSSRVSLTF HEPKLSHVEG YESVVPMIPN
       550        560        570        580        590        600
EKQSSPRVLE TREGGSYCDV YSDKTPDCSL GSSWQDTDWF TPQCSSDRGC VGIGEDFNIT
       610        620        630        640        650        660
PIDTAEFDSY DEKVGSKKYL SSVNVGSSVT GSFCLSSEWS PMYSTPSATK WESEYQKGCR
       670        680        690        700        710        720
ILEQSLRLGR MPDPEFCFSA ANNIKFDHEV IPEMDCCETG TDSFTAIQNC TQLADKICKS
       730        740        750        760        770        780
SWGHADDVRI DQYSIRKEKF SYMDGTQNNA GKQRSKRSRS APPFYREKKR FISLSCKSDT
       790        800        810        820        830        840
KPKNSDPSEP DDLECLTQPC NASQMHLKCS ILDDVSYDHI QETEKRLSSA SDLKASAGCR
       850        860        870        880        890        900
TVHSETQDED VHEDFSSEEF LDPIKSTTKW RHNCAVSQVP KESHELHGQD GVFDISSGLL
       910        920        930        940        950        960
HLRSDESLVP ESINRHSLED AKVLQQVDKK YIPIVACGTV AIVDQHAADE RIRLEELRTK
       970        980        990       1000       1010       1020
VLAGKARTVT YLSADQELVL PEMGYQLLQS YSEQIRDWGW ICNITVEGST SFKKNMSIIQ
      1030       1040       1050       1060       1070       1080
RKPTPITLNA VPCILGVNLS DVDLLEFLQQ LADTDGSSTI PPSVLRVLNS KACRGAIMFG
      1090       1100       1110       1120       1130       1140
DSLLPSECSL IIDGLKQTSL CFQCAHGRPT TVPLVDLKAL HKQIAKLSGR QVWHGLQRRE
      1150
ITLDRAKSRL DNAKS    

Encoded by MLH3 gene


OTHER NAME(S):
ATMLH3
F8D20.30
F8D20_30
MLH3
MUTL protein homolog 3


DESCRIPTION:
DNA mismatch repair protein similar to MutL. Required for normal levels of meiotic crossovers


Nucleic acid sequence

        10         20         30         40         50         60
atgaagacga tcaagccctt gccggaagga gttcgtcact ccatgcgttc tggaattatc
        70         80         90        100        110        120
atgttcgaca tggcgagggt cgtggaagaa ctcgtcttca acagtctcga tgctggggcg
       130        140        150        160        170        180
accaaggtgt ctatcttcgt gggtgttgtt tcatgctctg tgaaagttgt ggatgatgga
       190        200        210        220        230        240
tcaggcgttt caagagatga tttggttttg ttgggagaaa gatatgctac ttcaaagttt
       250        260        270        280        290        300
cacgacttca ccaacgtgga gacagctagt gaaacttttg gatttcgtgg agaggcctta
       310        320        330        340        350        360
gcttcaatat cagatatctc gttactggag gttaggacaa aagctattgg gaggcctaat
       370        380        390        400        410        420
ggttatcgaa aggttatgaa gggatccaag tgtctacatc ttggaattga tgatgataga
       430        440        450        460        470        480
aaagactctg gcacgacggt aactgtccga gatctatttt acagtcagcc agtgagacga
       490        500        510        520        530        540
aaatatatgc aatccagccc caagaaagtt ttggaatcta tcaaaaagtg tgtgttccgg
       550        560        570        580        590        600
attgcccttg tgcactccaa tgtttccttc agtgttcttg atatcgaaag tgatgaagag
       610        620        630        640        650        660
cttttccaaa ccaatccttc ttcttcagca ttctcactac tgatgagaga tgcagggacc
       670        680        690        700        710        720
gaagctgtaa attcgctttg taaagtaaac gttacagatg gcatgctgaa tgtctctggt
       730        740        750        760        770        780
tttgagtgtg cggatgactg gaagcctacg gatgggcaac aaacaggaag acgcaataga
       790        800        810        820        830        840
cttcaatcca accctggtta cattctgtgc atagcatgtc cacgccgtct ttatgaattc
       850        860        870        880        890        900
tcgtttgaac catcaaagac gcacgttgag ttcaagaagt ggggacctgt acttgccttt
       910        920        930        940        950        960
atagaaagaa tcactctagc caactggaag aaagatagaa ttcttgaact ttttgatggg
       970        980        990       1000       1010       1020
ggagctgata tactggcaaa aggtgataga caagacctga ttgatgacaa aattagactt
      1030       1040       1050       1060       1070       1080
caaaacggca gccttttctc aattcttcat tttctggatg cagattggcc agaagctatg
      1090       1100       1110       1120       1130       1140
gaacctgcaa aaaagaagct gaagagaagt aatgatcatg caccttgtag ttctctcttg
      1150       1160       1170       1180       1190       1200
tttccgtctg ctgactttaa acaagatggt gattattttt ctccacgaaa ggatgtatgg
      1210       1220       1230       1240       1250       1260
tctccagaat gtgaagtcga actgaaaatt cagaatccca aagagcaagg tactgtagct
      1270       1280       1290       1300       1310       1320
ggatttgaaa gccggactga ttctcttcta cagtcacgtg acatagaaat gcaaacgaat
      1330       1340       1350       1360       1370       1380
gaagacttcc cacaagttac tgacctcctt gaaacaagct tggttgctga ctctaagtgc
      1390       1400       1410       1420       1430       1440
cgtaaacagt ttctaacaag atgtcagatt accacacctg tcaatatcaa ccatgatttt
      1450       1460       1470       1480       1490       1500
atgaaagatt cagacgtgtt aaattttcag tttcaaggat tgaaagatga gttggatgtc
      1510       1520       1530       1540       1550       1560
agcaattgca ttggaaagca tctcttgcgt ggttgctctt caagagtaag cctaaccttt
      1570       1580       1590       1600       1610       1620
catgagccta aactatctca tgttgaaggg tatgaatccg tcgtgcctat gatacctaat
      1630       1640       1650       1660       1670       1680
gaaaaacaaa gtagtccgcg ggtcctagag accagagaag gtggttcgta ctgtgatgtt
      1690       1700       1710       1720       1730       1740
tattctgata agactcctga ttgttcccta gggagttcat ggcaggatac tgattggttt
      1750       1760       1770       1780       1790       1800
actccacagt gttcctcaga taggggatgt gttggaattg gagaagattt taacattacc
      1810       1820       1830       1840       1850       1860
cccatagata ctgcggaatt tgattcttat gatgaaaaag ttggtagtaa aaagtatctt
      1870       1880       1890       1900       1910       1920
tcttctgtca atgtggggag ctctgttact ggtagtttct gtttaagttc tgagtggtct
      1930       1940       1950       1960       1970       1980
ccaatgtact ccacaccttc tgcgaccaag tgggagtctg agtaccagaa aggttgtcga
      1990       2000       2010       2020       2030       2040
attcttgaac agagtttgag actgggaagg atgcctgacc ctgaattttg tttcagtgca
      2050       2060       2070       2080       2090       2100
gctaacaaca tcaaatttga ccacgaggtc atacctgaaa tggattgctg tgaaaccggt
      2110       2120       2130       2140       2150       2160
acagactctt tcacagctat tcagaactgc actcagttag ctgataaaat ttgcaagtct
      2170       2180       2190       2200       2210       2220
tcgtgggggc atgcagatga tgtgcgtatt gaccaatata gtatcaggaa ggaaaagttc
      2230       2240       2250       2260       2270       2280
agttatatgg atggcacaca gaacaatgct ggtaaacaaa ggtcaaaaag aagtcgatct
      2290       2300       2310       2320       2330       2340
gctcctccat tttatcgaga gaagaagaga tttatcagct taagttgtaa atcagacaca
      2350       2360       2370       2380       2390       2400
aaaccaaaga actctgatcc atcagaacct gatgatctgg agtgtttgac acaaccttgt
      2410       2420       2430       2440       2450       2460
aatgcatctc aaatgcatct taagtgcagc atccttgatg atgtgtcgta tgaccacata
      2470       2480       2490       2500       2510       2520
caagaaacag aaaaaagatt gagttctgcc tcagacttga aagcatctgc tggttgcagg
      2530       2540       2550       2560       2570       2580
actgtgcact cagagaccca agatgaggat gtgcacgaag acttcagctc agaggaattt
      2590       2600       2610       2620       2630       2640
ctggatccaa ttaaatccac aacaaaatgg cgccataact gtgcggtctc tcaggttccc
      2650       2660       2670       2680       2690       2700
aaggaatcac acgagcttca tggtcaagat ggtgtatttg atatatcttc gggacttctg
      2710       2720       2730       2740       2750       2760
cacttacgat ccgatgaatc cttggttcct gaatctatca acagacactc ccttgaagat
      2770       2780       2790       2800       2810       2820
gccaaggttc tacaacaggt tgataaaaaa tatatcccaa tcgttgcttg tggaacagtt
      2830       2840       2850       2860       2870       2880
gccatcgttg atcagcatgc tgccgatgaa agaattcgtt tggaagagct gcgtacaaag
      2890       2900       2910       2920       2930       2940
gtcctggcag ggaaagcgag gacagtcacc tacttgagtg cagaccaaga gttggtactg
      2950       2960       2970       2980       2990       3000
ccggagatgg gttatcagtt actccagagt tattcagagc agataagaga ctggggttgg
      3010       3020       3030       3040       3050       3060
atctgcaaca ttactgtaga agggtcaacg tcctttaaga aaaacatgag catcatccag
      3070       3080       3090       3100       3110       3120
cggaaaccaa caccaatcac acttaatgcg gttccatgca ttctgggtgt aaatctatca
      3130       3140       3150       3160       3170       3180
gatgttgatc tattagagtt tcttcagcag cttgctgata ctgacggatc atcaactatt
      3190       3200       3210       3220       3230       3240
cctccatctg ttcttcgagt cctaaattcc aaagcctgta gaggtgcaat tatgtttgga
      3250       3260       3270       3280       3290       3300
gatagtctgt taccgtcaga atgctcttta atcattgatg gactgaagca gacctcactt
      3310       3320       3330       3340       3350       3360
tgtttccagt gtgctcatgg gcgacctaca acagttcctc ttgtcgattt gaaggcattg
      3370       3380       3390       3400       3410       3420
cacaaacaga tagcaaagct cagtggaaga caagtgtggc atggcttaca acgcagagaa
      3430       3440       3450       3460
attacacttg atcgtgcaaa atcacgctta gacaacgcta aaagttaa 

Last modification date: Oct. 2, 2011