Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]


RELATED PATHWAY(S):
base excision repair (BER)


Amino acids sequence

        10         20         30         40         50         60
MKTAKGKDKV KTTKEALKPV DDRKVGKRKA PAEKPTKRET RKEKKAKKDP NKPKRAPSAF
        70         80         90        100        110        120
FVFLEDFRVT FKKENPNVKA VSAVGKAGGQ KWKSMSQAEK APYEEKAAKR KAEYEKQMDA
       130        140        150        160        170
YNKNLEEGSD ESEKSRSEIN DEDEASGEEE LLEKEAAGDD EEEEEEEDDD DDDDEEED

Encoded by HMGB1 gene


OTHER NAME(S):
high mobility group B1
HMGB1
NFD1
NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D1


DESCRIPTION:
Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha. In interphase cells, HMGB1 is found throughout the nucleus, whereas in mitotic cells it is not chromatin-associated.


Nucleic acid sequence

        10         20         30         40         50         60
atgaaaacag caaaggggaa agataaagtt aagaccacaa aggaagcctt gaagccagtt
        70         80         90        100        110        120
gatgacagaa aggtgggaaa gaggaaggca ccggctgaga agcctactaa acgagagact
       130        140        150        160        170        180
cgtaaagaga agaaggctaa aaaggaccca aacaaaccaa aaagagctcc tagtgccttc
       190        200        210        220        230        240
tttgtctttc tagaagattt tagggtcacg ttcaagaaag aaaatccaaa tgtgaaggcc
       250        260        270        280        290        300
gtctctgctg ttgggaaagc tggagggcag aaatggaagt caatgtctca agctgaaaaa
       310        320        330        340        350        360
gctccatatg aagagaaagc tgcaaaaagg aaagctgaat atgagaagca aatggatgca
       370        380        390        400        410        420
tacaacaaaa acttggagga agggagtgat gaatctgaaa agtctagatc tgagataaat
       430        440        450        460        470        480
gatgaagatg aagccagtgg ggaggaagaa ctattagaga aggaagcggc aggtgatgat
       490        500        510        520        530
gaagaagaag aagaggaaga agatgacgat gatgatgacg acgaggaaga agactaa

Last modification date: Oct. 2, 2011