Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]

FULL NAME: Proliferating cell nuclear antigen 2


DESCRIPTION:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity).

STRUCTURE SIMILARITY:
Belongs to the PCNA family.


RELATED PATHWAY(S):
DNA replication
base excision repair (BER)
nucleotide excision repair (NER)
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MLELRLVQGS LLKKVLEAVK DLVNDANFDC STTGFSLQAM DSSHVALVSL LLRSEGFEHY
        70         80         90        100        110        120
RCDRNLSMGM NLGNMSKMLK CAGNDDIITI KADDGSDTVT FMFESPTQDK IADFEMKLMD
       130        140        150        160        170        180
IDSEHLGIPD AEYHSIVRMP SGEFSRICKD LSSIGDTVVI SVTKEGVKFS TAGDIGTANI
       190        200        210        220        230        240
VLRQNTTVDK PEDAIVIEMN EPVSLSFALR YMNSFTKATP LSETVTISLS SELPVVVEYK
       250        260
VAEMGYIRYY LAPKIEEEED TKPE   

Encoded by PCNA2 gene


OTHER NAME(S):
A. THALIANA PROLIFERATING CELL NUCLEAR ANTIGEN 2
ATPCNA2
F16P2.5
F16P2_5
PCNA2
proliferating cell nuclear antigen 2


DESCRIPTION:
Functionally interacts with POLH to repair DNA damaged by UVB damage.


Nucleic acid sequence

        10         20         30         40         50         60
atgttggagc ttcgtttagt tcaaggttct ctactgaaga aggttctaga agcggtcaaa
        70         80         90        100        110        120
gatctggtga acgatgcgaa cttcgactgt tcgaccacag ggttctcgct tcaagctatg
       130        140        150        160        170        180
gattcgagcc atgtcgcgtt ggtgtctctt ttgcttagat ctgaaggttt cgagcactat
       190        200        210        220        230        240
agatgcgata ggaacctctc tatgggaatg aatcttggta atatgtctaa gatgctgaaa
       250        260        270        280        290        300
tgtgctggaa atgatgatat catcaccatc aaagctgatg atggtagcga cactgttact
       310        320        330        340        350        360
ttcatgtttg agagtcccac acaagacaag attgcagatt ttgagatgaa gctgatggat
       370        380        390        400        410        420
atcgacagtg agcatttagg aattcctgat gctgagtacc actcgattgt gagaatgcct
       430        440        450        460        470        480
tctggtgaat tttccaggat atgcaaagat ctcagtagca ttggtgacac agttgtgatc
       490        500        510        520        530        540
tcggtaacaa aagaaggggt gaagttttca acagcaggtg atatcgggac agcaaacatt
       550        560        570        580        590        600
gtgctcaggc agaatactac cgtcgacaaa cctgaagatg ctattgtgat agagatgaac
       610        620        630        640        650        660
gagcctgttt cgctttcatt tgcattgagg tacatgaact ccttcacaaa ggctactcca
       670        680        690        700        710        720
ttgtcggaaa ctgtgaccat cagtttgtcc tctgagttac cggtcgtggt ggagtacaag
       730        740        750        760        770        780
gtggctgaga tgggttacat tcgatactat ctggcgccta agattgaaga agaagaagac
       790
accaaaccag aataa    

Last modification date: Oct. 2, 2011