Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]

FULL NAME: Protein PROLIFERA


DESCRIPTION:
Required for megagametophyte and embryo development.

STRUCTURE SIMILARITY:
Contains 1 MCM domain.
Belongs to the MCM family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MKDHDFDGDK GLAKGFLENF ADANGRSKYM EILQEVSNRK IRAIQVDLDD LFNYKDESEE
        70         80         90        100        110        120
FLGRLTENTR RYVSIFSAAV DELLPEPTEA FPDDDHDILM TQRADDGTDN PDVSDPHQQI
       130        140        150        160        170        180
PSEIKRYYEV YFKAPSKGRP STIREVKASH IGQLVRISGI VTRCSDVKPL MAVAVYTCED
       190        200        210        220        230        240
CGHEIYQEVT SRVFMPLFKC PSSRCRLNSK AGNPILQLRA SKFLKFQEAK MQELAEHVPK
       250        260        270        280        290        300
GHIPRSMTVH LRGELTRKVS PGDVVEFSGI FLPIPYTGFK ALRAGLVADT YLEATSVTHF
       310        320        330        340        350        360
KKKYEEYEFQ KDEEEQIARL AEDGDIYNKL SRSLAPEIYG HEDIKKALLL LLVGAPHRQL
       370        380        390        400        410        420
KDGMKIRGDV HICLMGDPGV AKSQLLKHII NVAPRGVYTT GKGSSGVGLT AAVMRDQVTN
       430        440        450        460        470        480
EMVLEGGALV LADMGICAID EFDKMDESDR TAIHEVMEQQ TVSIAKAGIT TSLNARTAVL
       490        500        510        520        530        540
AAANPAWGRY DLRRTPAENI NLPPALLSRF DLLWLILDRA DMDSDLELAK HVLHVHQTEE
       550        560        570        580        590        600
SPALGFEPLE PNILRAYISA ARRLSPYVPA ELEEYIATAY SSIRQEEAKS NTPHSYTTVR
       610        620        630        640        650        660
TLLSILRISA ALARLRFSES VAQSDVDEAL RLMQMSKISL YADDRQKAGL DAISDTYSII
       670        680        690        700        710
RDEAARSKKT HVSYANALNW ISRKGYSEAQ LKECLEEYAA LNVWQIDPHT FDIRFI

Encoded by PRL gene


OTHER NAME(S):
MCM7
PRL
PROLIFERA
T10M13.7
T10M13_7


DESCRIPTION:
Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.


Nucleic acid sequence

        10         20         30         40         50         60
atgaaagacc acgatttcga cggcgacaaa gggcttgcca agggatttct cgagaatttc
        70         80         90        100        110        120
gccgacgcta atggcagatc taagtacatg gagattctcc aagaggtttc aaatcgtaag
       130        140        150        160        170        180
attcgagcta ttcaagtcga tctcgatgac ttattcaatt ataaagatga aagtgaggag
       190        200        210        220        230        240
tttctcggac ggttgacgga aaacactcgc cgatatgttt caattttctc cgccgctgtt
       250        260        270        280        290        300
gacgagttgt tacccgaacc aacggaagcg tttccagatg atgatcatga tattctcatg
       310        320        330        340        350        360
actcagagag cagatgatgg gactgataat ccagatgttt ctgatcctca tcagcagatt
       370        380        390        400        410        420
ccttctgaga ttaaaagata ttatgaggtt tattttaaag ctccttcaaa gggaaggcca
       430        440        450        460        470        480
tctaccatca gggaggttaa ggcttcacac attgggcaac ttgttaggat atctggtatt
       490        500        510        520        530        540
gtgacccgtt gttccgatgt caagccattg atggcggttg ctgtttacac atgtgaagat
       550        560        570        580        590        600
tgtggtcatg agatttacca ggaagttaca tctagagtct tcatgccttt gtttaagtgt
       610        620        630        640        650        660
ccttctagtc gctgtcgtct taatagtaaa gccgggaatc ctattcttca gctcagagca
       670        680        690        700        710        720
tcaaagtttc taaagtttca ggaggccaag atgcaagagt tggctgaaca tgttcccaaa
       730        740        750        760        770        780
gggcatattc cgaggtctat gactgttcat ctaagaggag agttgacaag aaaggtatca
       790        800        810        820        830        840
ccaggtgatg ttgttgagtt ctcagggatt tttcttccca ttccttacac tgggtttaag
       850        860        870        880        890        900
gcacttcgag ctggcttagt agcagacacc tatctggaag caacgtctgt tactcatttc
       910        920        930        940        950        960
aagaagaaat atgaggaata tgagtttcag aaagatgagg aagaacagat tgcacgtttg
       970        980        990       1000       1010       1020
gctgaggatg gtgacatata caataagctg tcgcgatccc tggcccctga gatttatgga
      1030       1040       1050       1060       1070       1080
catgaagata ttaagaaagc tttgcttctc cttcttgtgg gtgctcctca caggcaatta
      1090       1100       1110       1120       1130       1140
aaggatggaa tgaagattag aggagatgtg catatctgtc tgatgggtga tcctggagtt
      1150       1160       1170       1180       1190       1200
gccaagagtc agcttctcaa gcacattata aatgttgctc caaggggagt ctacacaaca
      1210       1220       1230       1240       1250       1260
ggcaaaggta gcagtggagt tggtctaact gccgctgtta tgagagatca agtaacaaat
      1270       1280       1290       1300       1310       1320
gagatggttt tagaaggagg agcactggtg ctggctgaca tgggaatctg tgcaattgat
      1330       1340       1350       1360       1370       1380
gagtttgata agatggatga atcagatcgt actgctattc atgaggtcat ggagcagcaa
      1390       1400       1410       1420       1430       1440
actgtaagca ttgcaaaagc tgggattacc acgtctttga atgctcgaac agctgttctt
      1450       1460       1470       1480       1490       1500
gctgcagcca atccagcctg gggaagatat gatttgcgaa gaactccagc tgaaaacatt
      1510       1520       1530       1540       1550       1560
aatcttccac cggcccttct ttcaagattc gatctgctgt ggttgatctt agatcgagct
      1570       1580       1590       1600       1610       1620
gacatggaca gtgaccttga attggcaaag catgtgcttc acgtacatca gacagaagaa
      1630       1640       1650       1660       1670       1680
tctcctgcgc ttggtttcga gcctctggaa cccaacattc tccgtgcata catttcagct
      1690       1700       1710       1720       1730       1740
gcaaggagat tatcaccata cgtcccagca gagttggagg aatatatagc aactgcttat
      1750       1760       1770       1780       1790       1800
tccagcatca ggcaagaaga agcgaaatca aatactcctc attcttacac aacagtgagg
      1810       1820       1830       1840       1850       1860
acactgctca gcattctgcg catatccgct gcattagcaa ggttgagatt ttcagaatca
      1870       1880       1890       1900       1910       1920
gtggcacaga gtgatgtgga tgaggcgctt agactaatgc agatgtcgaa aatatcattg
      1930       1940       1950       1960       1970       1980
tatgctgatg accgacaaaa agcaggacta gatgcaatat cagacacata ctcaatcata
      1990       2000       2010       2020       2030       2040
agagacgaag ctgcaagatc aaaaaagacc catgtgagct acgcaaatgc cctgaactgg
      2050       2060       2070       2080       2090       2100
atctccagaa agggatacag tgaggctcag ctaaaggagt gtttggagga atatgcagct
      2110       2120       2130       2140       2150
ttgaatgttt ggcagattga tcctcacacc tttgacatcc gttttatctg a

Last modification date: Oct. 2, 2011