Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]

FULL NAME: DNA gyrase subunit B, mitochondrial


DESCRIPTION:
DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner.

STRUCTURE SIMILARITY:
Contains 1 Toprim domain.
Belongs to the type II topoisomerase family.


SUBUNIT STRUCTURE:
Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis (By similarity).


CATALYTIC ACTIVITY:
ATP-dependent breakage, passage and rejoining of double-stranded DNA.


PROTEIN TYPE(S):
DNA topoisomerase


RELATED PATHWAY(S):
DNA replication
prokaryotic nucleoid remodeling


Amino acids sequence

        10         20         30         40         50         60
MALLQRASYL RLYYLRLMGS RPRLFSSSLS PALHRHSSTL SSPPFSSPSP SFRLKFQLTS
        70         80         90        100        110        120
VLSQRLIQRN AISSRFLSTE ASQETTTSKG YSSEQIQVLE GLDPVRKRPG MYIGSTGSRG
       130        140        150        160        170        180
LHHLVYEILD NAIDEAQAGY ASKVDVVLHA DGSVSVVDNG RGIPTDLHPA TKKSSLETVL
       190        200        210        220        230        240
TVLHAGGKFG GTSSGYSVSG GLHGVGLSVV NALSEALEVS VWRDGMEHKQ NYSRGKPITT
       250        260        270        280        290        300
LTCRVLPLES KGTKGTSIRF WPDKEVFTTA IEFDHNTIAG RIRELAFLNP KVTISLKKED
       310        320        330        340        350        360
DDPEKTQYSE YSFAGGLTEY VSWLNTDKNP IHDVLGFRRE INGATVDVAL QWCSDAYSDT
       370        380        390        400        410        420
MLGYANSIRT IDGGTHIEGV KASLTRTLNT LAKKSKTVKE KDISLSGEHV REGLTCIVSV
       430        440        450        460        470        480
KVPNPEFEGQ TKTRLGNPEV RKIVDQSVQE YLTEFLELHP DILESIISKS LNAYKAALAA
       490        500        510        520        530        540
KRARELVRSK SVLKSSSLPG KLADCSSTDP EVSEIFIVEG DSAGGSAKQG RDRRFQAILP
       550        560        570        580        590        600
LRGKILNIER KDEAAMYKNE EIQNLILGLG LGVKGEDFKK ENLRYHKIII LTDADVDGAH
       610        620        630        640        650        660
IRTLLLTFFF RYQRALFDAG CIYVGVPPLF KVERGKNAQY CYDDADLKKI TSNFPANASY
       670        680        690        700        710        720
NIQRFKGLGE MMPEQLWETT MNPETRILKQ LVVDDIAEAN MTFSSLMGAR VDVRKELIKN
       730
AATRINLQRL DI    

Encoded by GYRB2 gene


OTHER NAME(S):
DNA GYRASE B2
F21E1.50
F21E1_50
GYRB2


Nucleic acid sequence

        10         20         30         40         50         60
atggcgcttc ttcagagagc ttcttatctg cgtctctatt atttacggct catgggttct
        70         80         90        100        110        120
cgacctcgtc tcttctctag ctctctctct cctgctcttc accgtcacag ctcgacgctc
       130        140        150        160        170        180
tcctcgcctc cattttcctc tccaagtccc agtttcaggt taaagtttca gttaaccagt
       190        200        210        220        230        240
gttttgagtc aaagactgat acaacgaaat gctatttcat cgaggttctt gtctactgag
       250        260        270        280        290        300
gcttcccaag agactaccac atctaagggt tacagttctg aacagattca agtgctggaa
       310        320        330        340        350        360
ggcttagacc ctgtaagaaa acgtccagga atgtatatcg gaagcactgg atctcgtggt
       370        380        390        400        410        420
ttgcatcatt tggtttatga gatacttgac aacgcaattg atgaggctca agctggttat
       430        440        450        460        470        480
gcctcaaagg ttgatgtcgt cctacatgca gatggctcag ttagtgttgt ggacaatggg
       490        500        510        520        530        540
cgtgggatac ccacggattt gcatcctgcg acaaaaaagt cttccctgga gactgtgctt
       550        560        570        580        590        600
acggttttac atgcgggtgg caagtttggt ggcacgagta gtggctacag tgtgtctggt
       610        620        630        640        650        660
ggattacatg gtgtcggttt atcagtagta aatgctttgt ctgaggctct ggaggtctcg
       670        680        690        700        710        720
gtttggagag atgggatgga gcataagcaa aattattctc gtggaaagcc cataactaca
       730        740        750        760        770        780
cttacatgtc gcgtcctccc cctagagtca aaggggacta aagggacaag catcaggttt
       790        800        810        820        830        840
tggcctgaca aagaagtttt cacaactgca atcgagttcg accataacac cattgctgga
       850        860        870        880        890        900
cgaattaggg agcttgcatt tttgaatcca aaggttacca tctctttaaa aaaggaggat
       910        920        930        940        950        960
gatgatcctg aaaagaccca atatagtgaa tactcttttg ctggaggatt aactgaatat
       970        980        990       1000       1010       1020
gttagttggc taaatactga taagaatcca attcatgacg tgctgggttt caggagagag
      1030       1040       1050       1060       1070       1080
ataaatggtg ccaccgtgga cgttgccctt caatggtgct cagatgcata ttcagacaca
      1090       1100       1110       1120       1130       1140
atgctgggat atgccaatag cattcgcact attgatggtg gaacacacat cgaaggtgtg
      1150       1160       1170       1180       1190       1200
aaagcttcat taacaaggac tcttaatacc cttgcaaaaa agtcaaagac tgttaaggag
      1210       1220       1230       1240       1250       1260
aaagatatta gcttaagtgg ggaacatgtt agagagggat tgacctgtat cgtctcagtc
      1270       1280       1290       1300       1310       1320
aaggttccta atcctgagtt tgaaggtcaa acaaagacaa gattaggaaa tccagaggtg
      1330       1340       1350       1360       1370       1380
agaaaaattg ttgaccaatc agttcaggaa tatctcacag agtttttgga attgcatcca
      1390       1400       1410       1420       1430       1440
gatattcttg agagcattat ttccaaatcc cttaacgctt acaaggctgc tttggctgcc
      1450       1460       1470       1480       1490       1500
aagagggcaa gggagttggt caggtcgaaa agcgttttga agtcatcatc acttcctggg
      1510       1520       1530       1540       1550       1560
aaactggctg attgctcatc aacagatcct gaagtatctg aaatttttat agttgaagga
      1570       1580       1590       1600       1610       1620
gattctgctg gtggcagtgc gaaacagggc cgtgatagac gatttcaggc aattcttcct
      1630       1640       1650       1660       1670       1680
ttgagaggta aaattctgaa cattgaaaga aaggatgaag cagccatgta taagaatgaa
      1690       1700       1710       1720       1730       1740
gaaattcaaa atctaattct tggccttggc ctcggtgtga agggagaaga ttttaagaaa
      1750       1760       1770       1780       1790       1800
gaaaatttgc ggtaccataa gataatcatc ttaacagatg cagatgttga tggtgcacat
      1810       1820       1830       1840       1850       1860
atccggacac ttctgttgac ctttttcttc agatatcaga gagccttgtt tgatgcaggt
      1870       1880       1890       1900       1910       1920
tgcatatatg tcggtgttcc tcctctgttc aaggttgaaa ggggaaagaa tgcacaatat
      1930       1940       1950       1960       1970       1980
tgctatgatg atgcagacct taaaaagatc accagtaact tccctgcaaa cgcatcctac
      1990       2000       2010       2020       2030       2040
aacattcaaa ggttcaaagg tttgggagag atgatgcctg aacagctttg ggaaacgaca
      2050       2060       2070       2080       2090       2100
atgaatccag aaacaaggat actaaagcaa cttgttgtcg atgatatagc ggaagcaaac
      2110       2120       2130       2140       2150       2160
atgacattct catctcttat gggtgctcgg gtcgatgtcc ggaaagaact catcaaaaat
      2170       2180       2190
gctgcaacta ggatcaacct gcagcgtcta gacatataa  

Last modification date: Oct. 5, 2011