Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]

FULL NAME: Probable DNA gyrase subunit A, chloroplastic/mitochondrial


DESCRIPTION:
DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner.

STRUCTURE SIMILARITY:
Belongs to the topoisomerase GyrA/ParC subunit family.


SUBUNIT STRUCTURE:
Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis (By similarity).


CATALYTIC ACTIVITY:
ATP-dependent breakage, passage and rejoining of double-stranded DNA.


PROTEIN TYPE(S):
DNA topoisomerase


RELATED PATHWAY(S):
DNA replication
prokaryotic nucleoid remodeling


Amino acids sequence

        10         20         30         40         50         60
MTPVLCHSTA SIPNPNSLMS LSSTLRLSSS LLRRSFFRFP LTDPLCRLRR TEPSATRFFS
        70         80         90        100        110        120
SRTPRSGKFV VGAGKRGDEQ VKEESGANNG GLVVSGDESR IVPFELHKEA TESYMSYALS
       130        140        150        160        170        180
VLLGRALPDV RDGLKPVHRR ILFAMHELGM SSKKPYKKCA RVVGEVLGKF HPHGDTAVYD
       190        200        210        220        230        240
SLVRMAQSFS LRCPLIQGHG NFGSIDADPP AAMRYTECRL DPLAEAVLLS DLDQDTVDFV
       250        260        270        280        290        300
ANFDNSQKEP AVLPARLPAL LLNGASGIAV GMATNIPPHN LGELVDVLCA LIHNPEATLQ
       310        320        330        340        350        360
ELLEYMPAPD FPTGGIIMGN LGVLDAYRTG RGRVVVRGKA EVELLDPKTK RNAVIITEIP
       370        380        390        400        410        420
YQTNKATLVQ KIAELVENKT LEGISDIRDE SDRNGMRVVI ELKRGGDPAL VLNNLYRHTA
       430        440        450        460        470        480
LQSSFSCNMV GICDGEPKLM GLKELLQAFI DFRCSVVERR ARFKLSHAQQ RKHIIEGIVV
       490        500        510        520        530        540
GLDNVDEVIE LITKASSHSS ATAALQSEYG LSEKQAEAIL EITLRRLTAL ERKKFTDESS
       550        560        570        580        590        600
SLTEQITKLE QLLSTRTNIL KLIEQEAIEL KDRFSSPRRS MLEDSDSGDL EDIDVIPNEE
       610        620        630        640        650        660
MLMAVSEKGY VKRMKADTFN LQHRGTIGKS VGKLRVDDAM SDFLVCHAHD HVLFFSDRGI
       670        680        690        700        710        720
VYSTRAYKIP ECSRNAAGTP LVQILSMSEG ERVTSIVPVS EFAEDRYLLM LTVNGCIKKV
       730        740        750        760        770        780
SLKLFSGIRS TGIIAIQLNS GDELKWVRCC SSDDLVAMAS QNGMVALSTC DGVRTLSRNT
       790        800        810        820        830        840
KGVTAMRLKN EDKIASMDII PASLRKDMEE KSEDASLVKQ STGPWLLFVC ENGYGKRVPL
       850        860        870        880        890        900
SSFRRSRLNR VGLSGYKFAE DDRLAAVFVV GYSLAEDGES DEQVVLVSQS GTVNRIKVRD
       910        920        930        940        950
ISIQSRRARG VILMRLDHAG KIQSASLISA ADEEETEGTL SNEAVEAVSL 

Encoded by GYRA gene


OTHER NAME(S):
DNA GYRASE A
GYRA
T7M13.23


Nucleic acid sequence

        10         20         30         40         50         60
atgactccag tattatgcca ttccactgct tcaatcccta accctaactc tctcatgtct
        70         80         90        100        110        120
ctctcctcca ctctccgtct ctcttcctcc cttcttcgcc gctccttctt ccgattcccc
       130        140        150        160        170        180
ctcaccgacc cattatgccg tctccgccgc actgaaccct ccgccacgcg tttcttctcc
       190        200        210        220        230        240
tcccgtactc ctcggtccgg caaattcgtt gtcggtgctg gtaagcgcgg agatgagcag
       250        260        270        280        290        300
gtcaaggaag agtccggagc taacaatggc ggtttggttg tttctgggga cgaatctcgt
       310        320        330        340        350        360
attgtgcctt ttgagctaca taaggaagct actgagtcgt atatgtcgta tgcgctctct
       370        380        390        400        410        420
gttttgcttg gacgtgcttt gcctgatgtt agagacggac taaaaccagt acatcggaga
       430        440        450        460        470        480
attctctttg caatgcatga gttggggatg tcatctaaaa aaccatacaa gaaatgtgca
       490        500        510        520        530        540
agagttgttg gagaggttct tggtaaattc catccgcatg gagatactgc tgtttatgat
       550        560        570        580        590        600
tctcttgtta ggatggctca gagtttctcc ttgagatgtc cacttatcca aggccatgga
       610        620        630        640        650        660
aattttggct caatagatgc agatcctcct gctgctatgc gttacactga atgcagactc
       670        680        690        700        710        720
gatccactgg cagaggcagt actattgtct gatctggatc aagatacggt ggattttgtg
       730        740        750        760        770        780
gccaattttg ataactcaca aaaagaacca gcagtgttgc ctgctcgtct tcctgctttg
       790        800        810        820        830        840
ttgttgaatg gagcttctgg gattgcggtt ggcatggcaa caaatattcc ccctcataat
       850        860        870        880        890        900
cttggggagt tggtagacgt gctttgcgct ttaatccata atccagaagc aacgctgcaa
       910        920        930        940        950        960
gaactgctgg aatacatgcc tgcaccggat tttccaactg gaggaataat aatgggaaac
       970        980        990       1000       1010       1020
cttggggttt tggatgctta ccgaactggc cgagggcgag ttgtagttag aggaaaagct
      1030       1040       1050       1060       1070       1080
gaagttgaat tgttggatcc aaagacaaag cggaatgcag ttattatcac agagattcct
      1090       1100       1110       1120       1130       1140
taccagacaa acaaagctac acttgtccag aagattgccg aacttgttga aaataagacg
      1150       1160       1170       1180       1190       1200
ctagagggca taagtgacat acgtgacgag agtgatcgta atgggatgcg tgtggttatt
      1210       1220       1230       1240       1250       1260
gagctcaaaa gaggagggga tcctgcactt gtgcttaata atctttaccg gcatactgcc
      1270       1280       1290       1300       1310       1320
cttcaatcaa gcttcagctg caacatggtg ggtatctgcg atggagaacc caagctaatg
      1330       1340       1350       1360       1370       1380
ggattaaaag aactacttca ggcatttata gatttcaggt gttctgtcgt cgaaaggcgt
      1390       1400       1410       1420       1430       1440
gcaagattca agctttcaca tgcacaacaa cgaaagcata ttattgaggg tattgtggtt
      1450       1460       1470       1480       1490       1500
gggcttgaca atgtggacga agtaatcgaa ctcatcacga aggcctcaag tcattcctct
      1510       1520       1530       1540       1550       1560
gctactgctg ctttacaaag tgaatatggt ctttctgaga aacaagctga ggctatactg
      1570       1580       1590       1600       1610       1620
gagataactc ttcgaaggct aactgctctt gagcggaaaa agtttactga tgaaagtagt
      1630       1640       1650       1660       1670       1680
tcactaacag agcaaattac aaagttggag cagctattat caacccgaac aaacatccta
      1690       1700       1710       1720       1730       1740
aagttaatcg aacaagaagc aatagagctg aaggacagat tctcaagtcc caggcgttca
      1750       1760       1770       1780       1790       1800
atgttggagg attctgacag tggtgatcta gaagatatag atgttattcc aaatgaagag
      1810       1820       1830       1840       1850       1860
atgctgatgg cagtcagcga aaagggctat gtgaagagaa tgaaggccga tacattcaat
      1870       1880       1890       1900       1910       1920
cttcagcatc gtggaacaat tggcaaatct gttgggaaac taagagttga tgatgcaatg
      1930       1940       1950       1960       1970       1980
tctgactttc ttgtttgtca tgcacatgac catgtcctct ttttcagtga ccggggtata
      1990       2000       2010       2020       2030       2040
gtttactcaa cccgtgcata taaaattcca gaatgctctc gcaatgcagc tggtacacct
      2050       2060       2070       2080       2090       2100
ttggttcaga tattatccat gtcggaaggt gaaagagtaa cctccattgt tcctgttagc
      2110       2120       2130       2140       2150       2160
gagtttgctg aagatcgcta cctcctgatg cttacagtga atggctgcat caagaaagta
      2170       2180       2190       2200       2210       2220
tctttgaaat tattttcagg aatacgctca actggaatca tagcaattca gttgaattct
      2230       2240       2250       2260       2270       2280
ggtgatgaac tgaaatgggt tcgttgttgc tcaagcgacg atcttgtagc catggcatcc
      2290       2300       2310       2320       2330       2340
caaaatggaa tggtcgcctt gagtacatgt gatggtgttc gcacactgag cagaaataca
      2350       2360       2370       2380       2390       2400
aagggagtga ctgccatgag actcaagaat gaggataaga tagcgagcat ggacatcata
      2410       2420       2430       2440       2450       2460
cctgcatctc tgcggaaaga tatggaagag aagtcggaag atgcttcact tgtgaaacaa
      2470       2480       2490       2500       2510       2520
tccacgggtc catggctatt attcgtgtgt gagaatggct atggaaagcg tgttcctctg
      2530       2540       2550       2560       2570       2580
agtagcttcc ggcgttcgcg tctgaacaga gttggtttat ctggatacaa gtttgctgag
      2590       2600       2610       2620       2630       2640
gatgatcgtt tggctgctgt tttcgttgtt ggttactcct tggctgagga tggggagagt
      2650       2660       2670       2680       2690       2700
gatgagcaag tagttctggt gagccaaagc ggaactgtga accggatcaa agtcagggat
      2710       2720       2730       2740       2750       2760
atctcaatcc aatctcgcag agcacgggga gtgattctta tgcggctaga tcatgccggc
      2770       2780       2790       2800       2810       2820
aaaatccaat ctgcatctct gatctctgca gcagatgaag aagaaacaga aggaactcta
      2830       2840       2850
agtaatgaag ccgtagaagc cgttagcctg taa  

Last modification date: Oct. 5, 2011