Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]

FULL NAME: Cytosine-specific methyltransferase


STRUCTURE SIMILARITY:
Belongs to the C5-methyltransferase family.


CATALYTIC ACTIVITY:
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.


RELATED PATHWAY(S):
DNA replication
heterochromatin formation


Amino acids sequence

        10         20         30         40         50         60
MKTKAGKQKK RSVDSDDDVS RERRPKRATS GTNFKEKSLR FSEKYETVEA KKEQIVGDDE
        70         80         90        100        110        120
KEEKGVRFQS FGRVENWTIS GYEDGSPVIW ISTVIADYDC RKPSKKYKKL YDYFFEKACA
       130        140        150        160        170        180
CVEVCKNLST NPDTSLKELL AAVVRSMNGR KIFSSGGVIQ EFVISQGEFI YNQLAGLDET
       190        200        210        220        230        240
SKNHETKFVD NRVLVSLRDE SRKIHKAFSN VALRIDESKV LTSDQLMDGG EDEDLKYAKL
       250        260        270        280        290        300
LQEEEHMKSM DRSRNKRSST TSAPNKFYIK INEDEIAHDY PLPSYYKNTK DETDELVLFN
       310        320        330        340        350        360
AGYAVDARNL PCRTLHNWAL YNSDLMLISL EFLPMKPCAD IDVTYLGQIK EWKIDFGEDM
       370        380        390        400        410        420
IFVLLRTDMA WYRLGKPSEQ YAPWFEPILK TVRIGTSILA LLKNETRMAK LSYTDVIKRL
       430        440        450        460        470        480
CGLEENDQAY ISSTFFDVER YVIVHGQIIL QFLTECPDEY IKRCPFVTGL ASKMQDRHHT
       490        500        510        520        530        540
KWIIKKKRKM LQKGENLNLR RGKAPKVSKM KAMQATTTRL INRIWGEFYS IYSPEDPLEE
       550        560        570        580        590        600
IGAEEEFEEV EDVEEEDENE EEDTIQKAIE VQKADTLKKI RGSCKEMEIR WEGEILGETC
       610        620        630        640        650        660
AGEPLYGQAL VGGRKMDVGG AVILEVDDQG ETPLIYFVEY MFESSDNSKK LHGKLLQRGS
       670        680        690        700        710        720
ETVLGTAANE RELFLTNECL TVQLKDIKGT VSFEIRSRPW GHQYKKEHMA ADKLDRARAE
       730        740        750        760        770        780
ERKAKDLPIE YYCKSLYSPE KGGFFSLPRS DMGLGSGFCS SCKIRENEEE RSKTKLNDSK
       790        800        810        820        830        840
TRFLSNGIKY SVGDFVYQIP NYLSKDRGKR RPVFKYGRNV GLRAFVVCQI LDIVDLKEPK
       850        860        870        880        890        900
KGNTTSFEVK VRRFYRPDDV SAEEAYASDI QEVYYSEDTY ILPPEAIKGK CEVMKKTDMP
       910        920        930        940        950        960
LCREYPILDH VYFCDRFYDS SNGCLKKLPY NMMLKFSTIK DDTLLREKKT ETGSAMLLKP
       970        980        990       1000       1010       1020
DEVPKGKRLA TLDIFAGCGG LSYGLEKAGV SDTKWAIEYE EPAAQAFKQN HPKTTVFVDN
      1030       1040       1050       1060       1070       1080
CNVILRISWL RLLINDRAIM EKCGDVDDCI STTEAAELAT KLDENQKSTL PLPGQVDFIS
      1090       1100       1110       1120       1130       1140
GGPPCQGFSR LNRFSDGSWS KNQCQMILAF LSFADYFRPK YFLLENVKTF VSFNEGHTFH
      1150       1160       1170       1180       1190       1200
LTVASLLEMG YQVRFGLLEA GAYGISQPRK RAFIWAAAPN EVLPEWPEPM HVFNNPGFKI
      1210       1220       1230       1240       1250       1260
PLSQGLHYAA VQSTKFGAPF RSITVRDAIG DLPPIESGES KINKEEMRGS MTVLTDHICK
      1270       1280       1290       1300       1310       1320
KMNELNLIRC KKIPKTPGAD WRDLPDEHVN LSNGIVKNIV PNLLNKAKDH NGYKGLYGRL
      1330       1340       1350       1360       1370       1380
DWHGNLPTCI TNLQPMGLVG MCFHPDQDRI ISVRECARSQ GFPDSYKFSG NIKDKHRQVG
      1390       1400
NAVPPPLAFA LGRKLKEALH LRNI   

Encoded by MEE57 gene


OTHER NAME(S):
maternal effect embryo arrest 57
MEE57
T6G15.160
T6G15_160


Nucleic acid sequence

        10         20         30         40         50         60
atgaagacaa aagctgggaa acaaaagaag agaagtgttg actcggatga tgatgtctct
        70         80         90        100        110        120
agggaaagga gaccaaagcg agcaacatca ggcacaaact tcaaggagaa atctctccgt
       130        140        150        160        170        180
ttctctgaaa aatatgaaac tgttgaagcc aagaaagagc agatcgtggg tgatgacgaa
       190        200        210        220        230        240
aaggaagaaa aaggtgtgag gtttcaatct tttggtcggg tagagaactg gactatatct
       250        260        270        280        290        300
ggttatgaag atggttcccc ggtgatatgg atctcaactg tgattgcgga ttatgattgc
       310        320        330        340        350        360
cgtaaacctt ctaagaaata caagaaatta tatgattatt tctttgaaaa agcttgtgct
       370        380        390        400        410        420
tgtgtggagg tatgtaagaa cttgtccacg aatcctgata caagtcttaa agagcttctt
       430        440        450        460        470        480
gctgcggttg ttaggtcgat gaatggaaga aagatctttt ctagcggtgg agtcatccaa
       490        500        510        520        530        540
gagtttgtta tatcccaagg agaattcata tataaccaac tcgctggttt ggatgaaaca
       550        560        570        580        590        600
tccaagaatc atgaaaccaa atttgttgac aatcgtgttc ttgtttctct aagagatgag
       610        620        630        640        650        660
agtcgtaaaa ttcacaaggc tttctccaat gttgctctga ggattgatga gagcaaggtc
       670        680        690        700        710        720
ttgacatctg atcaactaat ggatggtggt gaggacgagg acctaaaata tgctaaacta
       730        740        750        760        770        780
ctgcaagagg aagaacatat gaaatctatg gatcggtcga gaaataagag aagttcaaca
       790        800        810        820        830        840
acttctgctc caaataagtt ctacattaag ataaatgaag atgagattgc ccatgattat
       850        860        870        880        890        900
cctctcccat cttactataa aaacaccaaa gatgaaacag atgaacttgt actctttaat
       910        920        930        940        950        960
gcgggctatg cggttgatgc gaggaaccta ccttgcagaa cacttcacaa ctgggcactt
       970        980        990       1000       1010       1020
tacaattctg atttaatgtt gatatctctt gagtttctcc cgatgaagcc atgtgctgat
      1030       1040       1050       1060       1070       1080
atcgatgtca cctatttggg tcagataaag gaatggaaga ttgattttgg ggaagacatg
      1090       1100       1110       1120       1130       1140
atatttgttc tattacgaac agatatggcc tggtatcggc tagggaaacc gtcagagcaa
      1150       1160       1170       1180       1190       1200
tatgctcctt ggttcgaacc tatattgaaa acagtaagaa ttgggacaag cattttggct
      1210       1220       1230       1240       1250       1260
ttgctcaaga atgaaacaag gatggctaag ctttcatata cagatgtcat aaaaagacta
      1270       1280       1290       1300       1310       1320
tgtgggctag aggagaacga tcaagcttac atttcttcta cgttctttga cgttgagaga
      1330       1340       1350       1360       1370       1380
tatgtgatcg tccatggaca aataatattg cagtttctta cagaatgtcc tgacgaatat
      1390       1400       1410       1420       1430       1440
atcaaaaggt gtccatttgt tactggtctt gcaagtaaaa tgcaggatag gcaccataca
      1450       1460       1470       1480       1490       1500
aaatggatca tcaagaagaa gagaaaaatg ttgcaaaagg gagagaattt gaatctaagg
      1510       1520       1530       1540       1550       1560
agaggcaagg cacctaaggt atccaagatg aaagccatgc aagcaacaac aactcggctt
      1570       1580       1590       1600       1610       1620
atcaatagaa tttggggtga gttttactcc atttattctc cagaagatcc gttggaggag
      1630       1640       1650       1660       1670       1680
attggtgcag aagaagagtt tgaagaggta gaagatgttg aagaggagga tgagaatgaa
      1690       1700       1710       1720       1730       1740
gaagaggaca ctatacaaaa agctattgag gttcaaaagg ctgatacact taagaaaatc
      1750       1760       1770       1780       1790       1800
cgaggtagtt gtaaggaaat ggaaataaga tgggaaggtg aaattcttgg agaaacttgt
      1810       1820       1830       1840       1850       1860
gctggtgagc ctctctatgg acaagccctt gttggaggta gaaagatgga tgttggtggg
      1870       1880       1890       1900       1910       1920
gctgtcattt tggaagttga tgatcaaggt gaaactccat taatctattt tgtggagtat
      1930       1940       1950       1960       1970       1980
atgtttgaga gttcagataa cagtaaaaag ctacatggga aactcttaca aagaggatct
      1990       2000       2010       2020       2030       2040
gagactgttc taggaacggc tgctaacgag agggaacttt tcttgactaa tgaatgtctt
      2050       2060       2070       2080       2090       2100
actgttcagc tcaaggacat aaaaggaaca gtaagttttg agattcgatc aaggccgtgg
      2110       2120       2130       2140       2150       2160
ggtcatcagt ataagaaaga gcacatggct gcagataaac ttgaccgggc aagagctgag
      2170       2180       2190       2200       2210       2220
gaaagaaaag ctaaagattt gccaatagaa tactactgca aaagcttgta ctcacctgag
      2230       2240       2250       2260       2270       2280
aaaggtggat tctttagtct tccaagaagt gatatgggtc taggttctgg attctgcagt
      2290       2300       2310       2320       2330       2340
tcatgtaaga taagagagaa tgaagaggaa aggtcaaaaa ctaaactcaa tgattcaaag
      2350       2360       2370       2380       2390       2400
acaagatttc tctccaatgg gatcaagtat tctgttgggg attttgttta tcaaatcccc
      2410       2420       2430       2440       2450       2460
aactacttaa gtaaagatag gggtaaaaga aggccagtgt ttaagtatgg taggaatgtt
      2470       2480       2490       2500       2510       2520
gggttaagag cctttgtggt ttgccaaata ctggatatag ttgacctaaa agaacccaaa
      2530       2540       2550       2560       2570       2580
aaaggtaata cgacttcttt tgaggtcaaa gtgagacggt tttataggcc cgatgatgtt
      2590       2600       2610       2620       2630       2640
tctgcagaag aggcttatgc ttcagacata caagaggttt attatagcga ggacacatat
      2650       2660       2670       2680       2690       2700
attcttcctc cagaagctat aaagggaaaa tgcgaagtta tgaaaaaaac tgatatgccc
      2710       2720       2730       2740       2750       2760
ttatgtcgtg agtatccaat tttagaccat gtctacttct gtgaccgttt ttatgactca
      2770       2780       2790       2800       2810       2820
tccaatggtt gtctcaagaa gttgccttac aatatgatgc tgaagttctc tactattaaa
      2830       2840       2850       2860       2870       2880
gacgacacac ttctaaggga aaagaagact gaaactggtt ctgcaatgct tctgaagccc
      2890       2900       2910       2920       2930       2940
gatgaggtac ctaaagggaa gcgtctagct acactagata tttttgccgg atgtggtggc
      2950       2960       2970       2980       2990       3000
ttgtcttatg gactagaaaa ggctggtgta tccgatacaa agtgggcgat cgagtatgaa
      3010       3020       3030       3040       3050       3060
gagccagctg cacaagcttt caaacaaaac catcccaaaa caacggtttt tgttgacaac
      3070       3080       3090       3100       3110       3120
tgcaatgtaa ttcttaggat cagttggttg agattattaa ttaatgacag ggctataatg
      3130       3140       3150       3160       3170       3180
gagaaatgtg gagatgttga tgattgtatc tctactacgg aggcagctga acttgcaacg
      3190       3200       3210       3220       3230       3240
aaacttgatg agaaccagaa gagtacccta ccacttcccg gtcaagtgga tttcatcagt
      3250       3260       3270       3280       3290       3300
ggagggcctc cgtgccaggg gttttctcgt ttaaataggt tcagtgacgg ctcttggagt
      3310       3320       3330       3340       3350       3360
aaaaaccagt gtcaaatgat attagcattc ttgtcttttg ctgactattt ccggccaaag
      3370       3380       3390       3400       3410       3420
tattttcttc tagagaacgt gaaaaccttt gtgtcattca atgaaggaca tacatttcat
      3430       3440       3450       3460       3470       3480
cttactgtag cttctcttct tgaaatgggt taccaggtga gatttggact cttggaggca
      3490       3500       3510       3520       3530       3540
ggagcatatg gaatatctca acctcgtaaa agagctttca tttgggctgc tgcaccaaac
      3550       3560       3570       3580       3590       3600
gaagttcttc cggaatggcc agagcccatg catgttttta ataatccggg ttttaaaatc
      3610       3620       3630       3640       3650       3660
ccactatctc aaggtttgca ttatgcggct gttcaaagta ctaaatttgg tgcacctttc
      3670       3680       3690       3700       3710       3720
cgttcaatca ctgtgagaga cgcgattggt gatcttccac caatagaaag cggagaatcc
      3730       3740       3750       3760       3770       3780
aagataaaca aagaggagat gagaggaagc atgactgttc tcactgatca tatatgtaaa
      3790       3800       3810       3820       3830       3840
aagatgaacg aactaaacct cattcgctgt aagaaaatcc ctaagacacc cggtgctgat
      3850       3860       3870       3880       3890       3900
tggcgtgacc taccagacga acatgtgaat ttatcaaatg ggattgtgaa aaacattgtt
      3910       3920       3930       3940       3950       3960
cccaatttgt taaacaaagc taaggaccac aacggttata agggactcta tggtagactg
      3970       3980       3990       4000       4010       4020
gactggcatg gcaatttacc cacttgcatc accaatcttc agcccatggg gttggtggga
      4030       4040       4050       4060       4070       4080
atgtgcttcc atcctgacca ggacagaatt atcagtgttc gtgaatgcgc ccgatctcag
      4090       4100       4110       4120       4130       4140
gggtttccgg atagctataa gttttcagga aatataaaag acaaacatag gcaggttgga
      4150       4160       4170       4180       4190       4200
aatgcagtcc ctccaccatt agcgtttgct cttggtcgga agcttaaaga agccctacac
      4210
cttaggaaca tctaa    

Last modification date: Oct. 2, 2011