Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]

FULL NAME: Cytosine-specific methyltransferase


STRUCTURE SIMILARITY:
Belongs to the C5-methyltransferase family.


CATALYTIC ACTIVITY:
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.


RELATED PATHWAY(S):
DNA replication
heterochromatin formation


Amino acids sequence

        10         20         30         40         50         60
METKVGKQKK RSVDSNDDVS KERRPKRAAA CRNFKEKPLR ISDKSETVEA KKEQNVVEEI
        70         80         90        100        110        120
VAIQLTSSLE SNDDPRPNRR LTDFVLHNSD GVPQPVEMLE LGDIFLEGVV LPLGDDKNEE
       130        140        150        160        170        180
KGVRFQSFGR VENWNISGYE DGSPGIWIST ALADYDCRKP ASKYKKIYDY FFEKACACVE
       190        200        210        220        230        240
VFKSLSKNPD TSLDELLAAV ARSMSGSKIF SSGGAIQEFV ISQGEFIYNQ LAGLDETAKN
       250        260        270        280        290        300
HETCFVENSV LVSLRDHESS KIHKALSNVA LRIDESQLVK SDHLVDGAEA EDVRYAKLIQ
       310        320        330        340        350        360
EEEYRISMER SRNKRSSTTS ASNKFYIKIN EHEIANDYPL PSYYKNTKEE TDELLLFEPG
       370        380        390        400        410        420
YEVDTRDLPC RTLHNWALYN SDSRMISLEV LPMRPCAEID VTVFGSGVVA EDDGSGFCLD
       430        440        450        460        470        480
DSESSTSTQS NVHDGMNIFL SQIKEWMIEF GAEMIFVTLR TDMAWYRLGK PSKQYAPWFE
       490        500        510        520        530        540
TVMKTVRVAI SIFNMLMRES RVAKLSYANV IKRLCGLEEN DKAYISSKLL DVERYVVVHG
       550        560        570        580        590        600
QIILQLFEEY PDKDIKRCPF VTGLASKMQD IHHTKWIIKR KKKILQKGKN LNPRAGLAHV
       610        620        630        640        650        660
VTRMKPMQAT TTRLVNRIWG EFYSIYSPEV PSEAIHEVEE EEIEEDEEED ENEEDDIEEE
       670        680        690        700        710        720
AVEVQKSHTP KKSRGNSEDM EIKWNGEILG ETSDGEPLYG RALVGGETVA VGSAVILEVD
       730        740        750        760        770        780
DPDETPAIYF VEFMFESSDQ CKMLHGKLLQ RGSETVIGTA ANERELFLTN ECLTVHLKDI
       790        800        810        820        830        840
KGTVSLDIRS RPWGHQYRKE NLVVDKLDRA RAEERKANGL PTEYYCKSLY SPERGGFFSL
       850        860        870        880        890        900
PRNDIGLGSG FCSSCKIKEE EEERSKTKLN ISKTGVFSNG IEYYNGDFVY VLPNYITKDG
       910        920        930        940        950        960
LKKGTSRRTT LKCGRNVGLK AFVVCQLLDV IVLEESRKAS NASFQVKLTR FYRPEDISEE
       970        980        990       1000       1010       1020
KAYASDIQEL YYSHDTYILP PEALQGKCEV RKKNDMPLCR EYPILDHIFF CEVFYDSSTG
      1030       1040       1050       1060       1070       1080
YLKQFPANMK LKFSTIKDET LLREKKGKGV ETGTSSGILM KPDEVPKEMR LATLDIFAGC
      1090       1100       1110       1120       1130       1140
GGLSHGLEKA GVSNTKWAIE YEEPAGHAFK QNHPEATVFV DNCNVILRAI MEKCGDVDDC
      1150       1160       1170       1180       1190       1200
VSTVEAAELV AKLDENQKST LPLPGQADFI SGGPPCQGFS GMNRFSDGSW SKVQCEMILA
      1210       1220       1230       1240       1250       1260
FLSFADYFRP KYFLLENVKK FVTYNKGRTF QLTMASLLEI GYQVRFGILE AGTYGVSQPR
      1270       1280       1290       1300       1310       1320
KRVIIWAASP EEVLPEWPEP MHVFDNPGSK ISLPRGLHYD TVRNTKFGAP FRSITVRDTI
      1330       1340       1350       1360       1370       1380
GDLPLVENGE SKINKEYRTT PVSWFQKKIR GNMSVLTDHI CKGLNELNLI RCKKIPKRPG
      1390       1400       1410       1420       1430       1440
ADWRDLPDEN VTLSNGLVEK LRPLALSKTA KNHNEWKGLY GRLDWQGNLP ISITDPQPMG
      1450       1460       1470       1480       1490       1500
KVGMCFHPEQ DRIITVRECA RSQGFPDSYE FSGTTKHKHR QIGNAVPPPL AFALGRKLKE
      1510
ALYLKSSLQH QS    

Encoded by gid:826477 gene


OTHER NAME(S):
F23J3.20
F23J3_20


Nucleic acid sequence

        10         20         30         40         50         60
atggagacaa aagttgggaa gcaaaagaag agaagtgttg actcaaatga tgatgtctct
        70         80         90        100        110        120
aaggaaagga gaccaaagcg agcagcagct tgcagaaact tcaaggagaa acctcttcgt
       130        140        150        160        170        180
atctctgaca aatctgaaac cgttgaagct aagaaagagc agaacgtggt ggaagagatc
       190        200        210        220        230        240
gtggcgatac agttaacttc ttctttggag agcaatgatg atcctcgtcc aaaccggagg
       250        260        270        280        290        300
ctgactgatt ttgttttaca taattcagat ggagttccac agcctgtgga gatgttggaa
       310        320        330        340        350        360
cttggtgaca tttttcttga aggtgttgtc ttacctttag gtgatgacaa aaacgaagaa
       370        380        390        400        410        420
aagggtgtga ggtttcaatc ttttggtcgt gtcgagaact ggaatatatc tggttatgaa
       430        440        450        460        470        480
gatggttccc cggggatatg gatatcaaca gcgttagcgg attacgattg ccgtaaacca
       490        500        510        520        530        540
gcttctaaat acaagaaaat atatgattat ttctttgaga aagcttgtgc ttgtgtggag
       550        560        570        580        590        600
gtgtttaaga gcttgtccaa gaatccggat acaagtcttg atgagcttct tgcggcggtt
       610        620        630        640        650        660
gcgaggtcga tgagcggaag caagatattt tctagcggtg gagccatcca agagtttgtt
       670        680        690        700        710        720
atatcccaag gagaattcat atataaccaa ctcgctggtc tggatgagac agccaagaat
       730        740        750        760        770        780
catgaaacat gctttgttga aaattctgtt cttgtttctc taagagatca tgaaagtagt
       790        800        810        820        830        840
aaaatccaca aggctttgtc taatgtggct ctgaggattg atgagagcca gctcgtgaaa
       850        860        870        880        890        900
tctgatcatt tagtggatgg tgctgaggcc gaggatgtaa gatatgctaa gttaatccaa
       910        920        930        940        950        960
gaagaagagt atcggatatc tatggagcgg tcgagaaata agagaagttc aacaacttct
       970        980        990       1000       1010       1020
gcttcgaata agttttacat taagatcaat gaacacgaga ttgccaatga ttatccactc
      1030       1040       1050       1060       1070       1080
ccgtcttact acaagaacac caaagaagaa acagatgagc ttttactctt tgaacctggc
      1090       1100       1110       1120       1130       1140
tatgaggtag atacaaggga cctaccttgt agaacacttc acaattgggc tctttacaac
      1150       1160       1170       1180       1190       1200
tctgattcac ggatgatatc attagaggtt cttcccatga ggccgtgtgc tgaaatcgat
      1210       1220       1230       1240       1250       1260
gtcaccgtat ttgggtcagg tgtggtggct gaagatgatg gaagtgggtt ttgtctcgat
      1270       1280       1290       1300       1310       1320
gattcagaga gctctacctc tacgcagtca aatgttcatg atgggatgaa catattcctt
      1330       1340       1350       1360       1370       1380
agtcaaataa aggaatggat gattgagttt ggagcagaaa tgatctttgt cacattacga
      1390       1400       1410       1420       1430       1440
actgacatgg cctggtatcg acttgggaaa ccgtcaaagc aatatgctcc atggtttgaa
      1450       1460       1470       1480       1490       1500
actgttatga aaacagtaag ggttgcgata agcattttca atatgctcat gagagaaagt
      1510       1520       1530       1540       1550       1560
agggttgcta agctttcata tgcaaatgtc ataaaaagac tttgtgggtt agaggagaac
      1570       1580       1590       1600       1610       1620
gataaagctt acatttcttc taagctcttg gatgttgaga gatatgttgt cgtccatgga
      1630       1640       1650       1660       1670       1680
caaattatct tgcagctttt cgaagagtat cctgacaagg atatcaaaag gtgtccattt
      1690       1700       1710       1720       1730       1740
gttactggtc ttgcaagtaa aatgcaggat atacaccaca caaaatggat catcaagagg
      1750       1760       1770       1780       1790       1800
aagaagaaaa ttctgcaaaa gggaaagaat ctgaatccga gggcgggctt ggcacatgtg
      1810       1820       1830       1840       1850       1860
gtaaccagaa tgaaacctat gcaagcaaca acaactcgcc tcgttaatag aatttgggga
      1870       1880       1890       1900       1910       1920
gagttttact ccatttactc tcctgaggtt ccatcggagg cgattcatga agtggaagaa
      1930       1940       1950       1960       1970       1980
gaggagattg aagaggatga agaggaggac gagaatgagg aagatgatat agaggaggaa
      1990       2000       2010       2020       2030       2040
gctgttgagg ttcaaaagtc tcatactcct aagaaaagta gaggtaattc tgaagatatg
      2050       2060       2070       2080       2090       2100
gagataaaat ggaatggtga gattcttgga gaaacttctg atggtgagcc tctctatgga
      2110       2120       2130       2140       2150       2160
agagcccttg ttggagggga aacagtggcg gtaggtagtg ctgtcatatt agaagttgat
      2170       2180       2190       2200       2210       2220
gatccagatg aaactccggc gatctatttt gtggagttca tgttcgagag ttcagatcag
      2230       2240       2250       2260       2270       2280
tgcaagatgc tacatgggaa actcttacaa agaggatctg agactgttat aggaacggct
      2290       2300       2310       2320       2330       2340
gctaacgaga gggaactgtt cttgactaat gaatgtctta ctgtccatct taaggacata
      2350       2360       2370       2380       2390       2400
aaaggaacag taagtctcga tattcgatca aggccgtggg ggcatcagta taggaaagag
      2410       2420       2430       2440       2450       2460
aacctcgttg tggataagct tgaccgggca agagcagaag aaagaaaagc taatggtttg
      2470       2480       2490       2500       2510       2520
ccaacagaat actactgcaa aagcttgtac tcacctgaga gaggtggatt ctttagtctt
      2530       2540       2550       2560       2570       2580
ccaaggaatg atattggtct tggttctgga ttctgtagtt cgtgtaagat aaaagaggaa
      2590       2600       2610       2620       2630       2640
gaagaggaaa ggtccaaaac taaactcaac atctcaaaga caggggtttt ctccaatggg
      2650       2660       2670       2680       2690       2700
atagagtatt ataatggaga ttttgtctat gtactcccca actacataac taaagatgga
      2710       2720       2730       2740       2750       2760
ttgaagaagg gtactagtag aagaacaact cttaagtgtg gtcggaacgt tgggttaaaa
      2770       2780       2790       2800       2810       2820
gcttttgttg tttgccaatt gctggatgtt attgttctag aagaatctag aaaagctagt
      2830       2840       2850       2860       2870       2880
aatgcttcat ttcaggttaa actgacaagg ttttataggc ccgaggacat ttctgaagaa
      2890       2900       2910       2920       2930       2940
aaggcttatg cttcagacat ccaagagttg tattatagcc atgacacata tattcttcct
      2950       2960       2970       2980       2990       3000
cctgaggctc tacaaggaaa atgtgaagta aggaagaaaa atgatatgcc cctatgtcgt
      3010       3020       3030       3040       3050       3060
gagtatccaa tattagatca tatcttcttc tgtgaagttt tctatgattc ctctactggt
      3070       3080       3090       3100       3110       3120
tatctcaagc agtttccagc gaatatgaag ctgaagttct ctactattaa agatgaaaca
      3130       3140       3150       3160       3170       3180
cttctaagag aaaagaaggg gaagggagta gagactggaa ctagttctgg aattcttatg
      3190       3200       3210       3220       3230       3240
aagcctgatg aggtacctaa agagatgcgt ctagctacac tagatatttt tgctggatgt
      3250       3260       3270       3280       3290       3300
ggtggtctat ctcatggact agaaaaggct ggtgtatcta atacaaagtg ggcgatcgag
      3310       3320       3330       3340       3350       3360
tatgaagagc cagctggtca tgcgtttaaa caaaaccatc ccgaagcaac ggtttttgtt
      3370       3380       3390       3400       3410       3420
gacaactgca atgtcattct tagggctata atggagaaat gtggagatgt cgatgattgt
      3430       3440       3450       3460       3470       3480
gtctctactg tggaggcagc tgaacttgta gctaaacttg atgagaacca aaagagtacc
      3490       3500       3510       3520       3530       3540
ctgccacttc ctggtcaagc ggatttcatc agcggagggc ctccatgcca agggttttct
      3550       3560       3570       3580       3590       3600
ggtatgaaca ggttcagtga cggttcgtgg agtaaagtac agtgtgaaat gatattagca
      3610       3620       3630       3640       3650       3660
ttcttgtcct ttgctgatta tttccgacca aagtattttc ttctcgagaa cgtaaagaaa
      3670       3680       3690       3700       3710       3720
tttgtgacat acaataaagg gagaacattt caacttacta tggcttctct tcttgaaata
      3730       3740       3750       3760       3770       3780
ggttaccaag taagatttgg aatcttggag gcaggtacat atggagtttc tcagcctcgt
      3790       3800       3810       3820       3830       3840
aaaagagtta taatttgggc agcttcacca gaagaagttc ttccagaatg gcctgagccg
      3850       3860       3870       3880       3890       3900
atgcatgtct ttgataatcc gggtagtaaa atctccttac ctcgaggttt acattatgat
      3910       3920       3930       3940       3950       3960
actgttcgta atactaaatt tggcgcaccg ttccgctcaa tcacggtgag agacacaatc
      3970       3980       3990       4000       4010       4020
ggcgatcttc cactagtaga aaacggagag tccaagataa acaaagagta tagaactact
      4030       4040       4050       4060       4070       4080
ccagtctcgt ggttccaaaa gaagataaga ggaaacatga gtgttctcac tgatcatatc
      4090       4100       4110       4120       4130       4140
tgcaaagggc tgaatgaact aaacctcatt cgatgtaaga aaatcccaaa gaggcctggt
      4150       4160       4170       4180       4190       4200
gctgattggc gtgacctgcc ggacgaaaac gtgacattat caaatggact cgtggaaaaa
      4210       4220       4230       4240       4250       4260
ctgcgtcctt tagctctatc aaagacagct aaaaaccaca acgaatggaa gggactctat
      4270       4280       4290       4300       4310       4320
ggtagattgg actggcaagg aaacttaccc atttccatca ccgatccgca gcccatgggt
      4330       4340       4350       4360       4370       4380
aaggtgggaa tgtgcttcca tccagaacag gacagaatta tcactgtccg tgaatgcgcc
      4390       4400       4410       4420       4430       4440
cgatctcagg ggtttccgga tagctatgag ttttcaggga cgacaaaaca caaacatagg
      4450       4460       4470       4480       4490       4500
cagattggaa atgcagtccc tccaccattg gcattcgctc tcggtcggaa gctcaaagaa
      4510       4520       4530
gccctatatc tcaagagttc tcttcaacac caatcataa  

Last modification date: Nov. 19, 2011