Arabidopsis thaliana (L.) Heynh. (mouse-ear cress) [ATH]

FULL NAME: Putative DNA (cytosine-5)-methyltransferase CMT1


DESCRIPTION:
May be involved in the CpXpG methylation and in gene silencing (By similarity).

STRUCTURE SIMILARITY:
Belongs to the C5-methyltransferase family.
Contains 1 chromo domain.
Contains 1 BAH domain.


CATALYTIC ACTIVITY:
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.


RELATED PATHWAY(S):
DNA replication
heterochromatin formation


Amino acids sequence

        10         20         30         40         50         60
MAARNKQKKR AEPESDLCFA GKPMSVVEST IRWPHRYQSK KTKLQAPTKK PANKGGKKED
        70         80         90        100        110        120
EEIIKQAKCH FDKALVDGVL INLNDDVYVT GLPGKLKFIA KVIELFEADD GVPYCRFRWY
       130        140        150        160        170        180
YRPEDTLIER FSHLVQPKRV FLSNDENDNP LTCIWSKVNI AKVPLPKITS RIEQRVIPPC
       190        200        210        220        230        240
DYYYDMKYEV PYLNFTSADD GSDASSSLSS DSALNCFENL HKDEKFLLDL YSGCGAMSTG
       250        260        270        280        290        300
FCMGASISGV KLITKWSVDI NKFACDSLKL NHPETEVRNE AAEDFLALLK EWKRLCEKFS
       310        320        330        340        350        360
LVSSTEPVES ISELEDEEVE ENDDIDEAST GAELEPGEFE VEKFLGIMFG DPQGTGEKTL
       370        380        390        400        410        420
QLMVRWKGYN SSYDTWEPYS GLGNCKEKLK EYVIDGFKSH LLPLPGTVYT VCGGPPCQGI
       430        440        450        460        470        480
SGYNRYRNNE APLEDQKNQQ LLVFLDIIDF LKPNYVLMEN VVDLLRFSKG FLARHAVASF
       490        500        510        520        530        540
VAMNYQTRLG MMAAGSYGLP QLRNRVFLWA AQPSEKLPPY PLPTHEVAKK FNTPKEFKDL
       550        560        570        580        590        600
QVGRIQMEFL KLDNALTLAD AISDLPPVTN YVANDVMDYN DAAPKTEFEN FISLKRSETL
       610        620        630        640        650        660
LPAFGGDPTR RLFDHQPLVL GDDDLERVSY IPKQKGANYR DMPGVLVHNN KAEINPRFRA
       670        680        690        700        710        720
KLKSGKNVVP AYAISFIKGK SKKPFGRLWG DEIVNTVVTR AEPHNQCVIH PMQNRVLSVR
       730        740        750        760        770        780
ENARLQGFPD CYKLCGTIKE KYIQVGNAVA VPVGVALGYA FGMASQGLTD DEPVIKLPFK
       790
YPECMQAKDQ I    

Encoded by CMT1 gene


OTHER NAME(S):
chromomethylase 1
CHROMOMETHYLASE 1
CMT1
DMT4
DNA METHYLTRANSFERASE 4
F23A5.9
F23A5_9


DESCRIPTION:
ecotype Kl-0 chromomethylase (CMT1). A plant line expressing an RNAi construct directed against DMT4 has reduced agrobacterium-mediated tumor formation.


Nucleic acid sequence

        10         20         30         40         50         60
atggcagcga gaaacaaaca aaagaaacgc gctgagccag agtcagatct gtgcttcgct
        70         80         90        100        110        120
ggcaaaccaa tgtctgttgt ggagtcgacg attcgatggc ctcatcgcta ccaatccaag
       130        140        150        160        170        180
aaaacaaagc tccaagctcc gaccaaaaaa cctgcaaata agggtggcaa aaaagaagat
       190        200        210        220        230        240
gaagagataa taaagcaagc taaatgccac tttgacaaag ctttggttga tggagttctc
       250        260        270        280        290        300
atcaacctaa acgacgatgt ctatgtcacg ggtctaccag ggaagctgaa attcattgca
       310        320        330        340        350        360
aaagttatcg agctctttga agctgatgat ggggtgccgt attgtcgctt tcgatggtac
       370        380        390        400        410        420
tatcggcctg aagatacttt aatcgaaaga ttttcccacc ttgtgcaacc aaagagagtg
       430        440        450        460        470        480
tttctctcaa atgatgagaa tgacaatcct ctcacctgca tctggtcaaa agtcaacatc
       490        500        510        520        530        540
gctaaagtcc cattacctaa gattacctcc agaatcgagc aaagggttat tcctccttgt
       550        560        570        580        590        600
gattactact acgatatgaa gtacgaagtt ccttatctca actttacaag tgcagatgat
       610        620        630        640        650        660
ggtagtgatg cctcatcaag tctttcaagt gactctgcct tgaattgctt tgaaaatctc
       670        680        690        700        710        720
cacaaggatg aaaaattctt attggatcta tacagtgggt gcggagcgat gtccacaggt
       730        740        750        760        770        780
ttctgcatgg gagcttccat atcaggagta aaattgatta cgaaatggtc tgtggatata
       790        800        810        820        830        840
aataagtttg cttgtgatag tcttaaactt aatcatcctg aaacagaggt gagaaacgaa
       850        860        870        880        890        900
gccgcagaag attttctagc tcttctcaaa gaatggaaaa ggctctgtga gaagttttct
       910        920        930        940        950        960
ctcgtttcaa gcaccgaacc agtggaatca atttctgagt tagaagatga agaagttgaa
       970        980        990       1000       1010       1020
gaaaatgatg acatagatga ggcaagtact ggtgctgaac tcgaacctgg agagtttgaa
      1030       1040       1050       1060       1070       1080
gtagaaaagt tccttggcat catgtttgga gatcctcaag gcacagggga aaagacactt
      1090       1100       1110       1120       1130       1140
caacttatgg taaggtggaa gggatacaat tctagttatg acacatggga accttactct
      1150       1160       1170       1180       1190       1200
ggcttaggca actgcaagga gaagctgaag gagtacgtga tagatgggtt taagtctcat
      1210       1220       1230       1240       1250       1260
ctcttaccac ttccgggtac tgtctacaca gtgtgcggtg ggcccccttg ccaagggatc
      1270       1280       1290       1300       1310       1320
agtgggtata accggtatag aaacaatgaa gcaccgcttg aagatcagaa gaaccagcaa
      1330       1340       1350       1360       1370       1380
cttttggtgt ttttagacat cattgacttc ctcaagccaa actatgtgct gatggaaaat
      1390       1400       1410       1420       1430       1440
gttgtagacc ttcttaggtt ttcaaagggt ttcctggcac gtcatgctgt agctagcttt
      1450       1460       1470       1480       1490       1500
gttgcgatga attaccagac gcggttgggc atgatggctg ctggatctta tgggctccct
      1510       1520       1530       1540       1550       1560
cagcttagaa acagggtttt tttatgggct gcacaaccat cagagaaact tcccccttat
      1570       1580       1590       1600       1610       1620
cccctcccaa cacatgaagt tgctaaaaag ttcaacacac ctaaagaatt caaagattta
      1630       1640       1650       1660       1670       1680
caagttggac gtattcaaat ggagttcctt aaattggaca acgctcttac gctggctgat
      1690       1700       1710       1720       1730       1740
gctattagtg atctgccacc ggtgacaaat tatgtggcaa atgatgtaat ggattataat
      1750       1760       1770       1780       1790       1800
gatgctgctc ctaagacaga gtttgagaac tttattagcc tcaaaagatc tgagacactt
      1810       1820       1830       1840       1850       1860
ttacccgcat ttggtggaga tccgacacgc aggttgtttg atcaccaacc cctcgtatta
      1870       1880       1890       1900       1910       1920
ggagatgatg acttggaaag agtttcctac ataccaaaac agaagggggc aaactatcgc
      1930       1940       1950       1960       1970       1980
gacatgcctg gtgttttagt tcacaacaac aaagcggaaa ttaatcctag gtttcgagca
      1990       2000       2010       2020       2030       2040
aagttgaaat ctggaaaaaa tgtggtccct gcttatgcaa tttcattcat aaaaggaaaa
      2050       2060       2070       2080       2090       2100
tcaaaaaagc cgtttggtag actttggggt gatgaaatcg ttaacactgt tgtgacaagg
      2110       2120       2130       2140       2150       2160
gctgaacctc acaaccagtg tgtaatccat ccaatgcaaa accgtgtgtt gtctgttcgt
      2170       2180       2190       2200       2210       2220
gagaatgcga gattacaggg gttccctgat tgttacaagc tctgtggaac aattaaggaa
      2230       2240       2250       2260       2270       2280
aagtacatcc aggttgggaa tgctgtggca gttcctgtag gggttgcatt aggatatgcc
      2290       2300       2310       2320       2330       2340
tttggtatgg cgagtcaagg actgacggat gatgaaccag taatcaagct gccattcaag
      2350       2360       2370
tatcccgaat gcatgcaggc aaaggatcaa atctga  

Last modification date: Oct. 2, 2011