Mus musculus L. (mouse) [MMU]

FULL NAME: DNA polymerase subunit gamma-2, mitochondrial


DESCRIPTION:
Mitochondrial polymerase processivity subunit. Stimulates the polymerase and exonuclease activities, and increases the processivity of the enzyme. Binds to ss-DNA.

CATALYTIC ACTIVITY:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MRCGGGARAC RRACRCWLSG YAGPADGTQQ PDAPEHAVAR EALVDLCRRR HFFSGTPQQL
        70         80         90        100        110        120
STAALLSGCH ARFGPLGVEL RKNLASQWWS SMVVFREQVF AVDSLHQEPG SSQPRDSAFR
       130        140        150        160        170        180
LVSPESIREI LQDREPSKEQ LVAFLENLLK TSGKLRATLL HGALEHYVNC LDLVNRKLPF
       190        200        210        220        230        240
GLAQIGVCFH PVSNSNQTPS SVTRVGEKTE ASLVWFTPTR TSSQWLDFWL RHRLLWWRKF
       250        260        270        280        290        300
AMSPSNFSSA DCQDELGRKG SKLYYSFPWG KEPIETLWNL GDQELLHTYP GNVSTIQGRD
       310        320        330        340        350        360
GRKNVVPCVL SVSGDVDLGT LAYLYDSFQL AENSFARKKS LQRKVLKLHP CLAPIKVALD
       370        380        390        400        410        420
VGKGPTVELR QVCQGLLNEL LENGISVWPG YSETVHSSLE QLHSKYDEMS VLFSVLVTET
       430        440        450
TLENGLIQLR SRDTTMKEMM HISKLRDFLV KYLASASNV  

Encoded by Polg2 gene

FULL NAME: polymerase (DNA directed), gamma 2, accessory subunit


Nucleic acid sequence

        10         20         30         40         50         60
atgcgctgcg gtggcggcgc cagggcctgc cgcagggcct gcaggtgctg gctgtccggg
        70         80         90        100        110        120
tacgcgggtc ccgcagatgg gacgcagcag cctgacgccc ccgagcatgc ggtggcccgc
       130        140        150        160        170        180
gaggcgctgg tagacctctg ccggaggagg cactttttca gcgggacgcc gcagcagctc
       190        200        210        220        230        240
agcacggctg ctctgctgag cgggtgccac gcgcgctttg gacctttggg tgtagagtta
       250        260        270        280        290        300
cgaaagaacc tagcctcaca gtggtggtcc tctatggtgg tgttcaggga gcaggtcttc
       310        320        330        340        350        360
gcggtggact ccctccacca ggagccgggc tcttcgcagc cgagggacag tgccttcagg
       370        380        390        400        410        420
ttagtctctc cagaaagtat acgcgaaatc ttgcaagaca gagagccgag taaggaacag
       430        440        450        460        470        480
ctagtggcat ttcttgagaa cttattaaaa acttctggga aactacgggc gactcttctt
       490        500        510        520        530        540
cacggtgcct tggagcacta tgttaattgc ctggatctgg taaacagaaa gctacctttc
       550        560        570        580        590        600
ggtcttgctc agattggagt ctgtttccat cctgtttcga acagcaatca gacacccagc
       610        620        630        640        650        660
agtgttacaa gagttggtga aaagacggaa gcttccttgg tatggtttac tcccacaagg
       670        680        690        700        710        720
acttcgagcc agtggcttga tttctggttg cgtcatcggc ttctgtggtg gagaaagttt
       730        740        750        760        770        780
gctatgagtc cctctaactt cagcagcgct gattgtcagg atgaattggg acgcaaggga
       790        800        810        820        830        840
agcaaacttt actacagctt cccctgggga aaggagccaa tagaaaccct gtggaaccta
       850        860        870        880        890        900
ggagatcaag aactcctaca cacatatcct ggaaatgtgt ctacgataca gggtcgagat
       910        920        930        940        950        960
gggcggaaaa acgtggttcc ttgcgttctg tctgtaagtg gggacgtaga cctgggcacg
       970        980        990       1000       1010       1020
ctggcttacc tctacgattc cttccagctg gcagagaact cctttgccag gaagaagagc
      1030       1040       1050       1060       1070       1080
ctccagagaa aggtgcttaa acttcaccct tgtttagccc ctattaaggt cgctttggat
      1090       1100       1110       1120       1130       1140
gtggggaaag gcccaacggt agaactccga caggtttgtc aagggctact taatgagtta
      1150       1160       1170       1180       1190       1200
ctagaaaatg ggatttctgt gtggcctggc tattcggaaa ctgtccattc ctcattagag
      1210       1220       1230       1240       1250       1260
caactccatt caaagtacga tgagatgagt gtcctcttct cagttctggt cactgagact
      1270       1280       1290       1300       1310       1320
acgctggaaa atgggctaat ccagctgcgg agcagagaca ccacgatgaa ggaaatgatg
      1330       1340       1350       1360       1370       1380
cacatatcca agctgagaga cttcctggtc aagtacctag cgtcagctag caatgtgtag

Last modification date: Oct. 2, 2011