Mus musculus L. (mouse) [MMU]

FULL NAME: DNA replication complex GINS protein SLD5


DESCRIPTION:
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA (By similarity).

STRUCTURE SIMILARITY:
Belongs to the GINS4/SLD5 family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MTEVLDLHGQ DSDGGSEEMV LTPAELIEKL EQAWMNEKFA PELLESKAEI VECVMEQLEH
        70         80         90        100        110        120
MEENLRRAKK GDLKVSIHRM EMERIRYVLS SYLRCRLMKI EKFFPHILEK EKVRSEGEPS
       130        140        150        160        170        180
SLSPEEFVFA KEYMDHTETH FKNVALKHMP PNLQKVDLLR AVPKPDLDSY VFLRVKERQE
       190        200        210        220
NILVEPEADE QRDYVIDLEV GSQHLIRYKT IAPLVASGAV QLI 

Encoded by Gins4 gene

FULL NAME: GINS complex subunit 4 (Sld5 homolog)


OTHER NAME(S):
2810037C03Rik
4933405K01Rik
Sld5


Nucleic acid sequence

        10         20         30         40         50         60
atgacggagg ttctggatct ccacggacag gactctgatg ggggtagtga ggagatggtc
        70         80         90        100        110        120
ctaactcctg cagagctcat tgaaaagctg gagcaggcct ggatgaatga aaagtttgcc
       130        140        150        160        170        180
cctgagctcc tggaaagcaa ggctgagatt gtcgaatgcg tcatggaaca gcttgagcac
       190        200        210        220        230        240
atggaagaaa atctcagaag agccaagaag ggggatctga aggtcagcat ccatcgcatg
       250        260        270        280        290        300
gagatggaga ggatccgcta tgtcctcagc agctatttgc ggtgtcgact catgaagata
       310        320        330        340        350        360
gagaagtttt tccctcacat cctagaaaag gagaaagtgc gcagtgaggg ggagccttcc
       370        380        390        400        410        420
agcctgtctc cagaggagtt tgtctttgcc aaagagtata tggaccacac ggagacccac
       430        440        450        460        470        480
tttaaaaacg ttgccttaaa gcacatgcct cccaacctgc agaaggtgga cctcttgagg
       490        500        510        520        530        540
gcagttccca aaccagacct agattcatac gtgtttctgc gagtgaaaga acgacaagaa
       550        560        570        580        590        600
aacatactag tagaaccaga agccgatgag cagagagact acgtgattga cttggaggtg
       610        620        630        640        650        660
ggctcacagc acttgatccg atacaaaacc atcgcacctc ttgttgcttc tggagcagtt
       670
cagctaatat aa    

Last modification date: Oct. 2, 2011