Homo sapiens L. (human) [HSA]


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MSEAYFRVES GALGPEENFL SLDDILMSHE KLPVRTETAM PRLGAFFLER SAGAETDNAV
        70         80         90        100        110        120
PQGFALLPRL ECSGVIWLTA ALTSQAPEIL PPQPPMWLVL QGSKLELPLW LAKGLFDNKR
       130        140        150        160        170        180
RILSVELPKI YQEGWRTVFS ADPNVVDLHK MGPHFYGFGS QLLHFDSPEN ADISQSLLQT
       190        200        210        220        230        240
FIGRFRRIMD SSQNAYNEDT SALVARLDEM ERGLFQTGQK GLNDFQCWEK GQASQITASN
       250
LVQNYKKRKF TDMED    

Encoded by GINS3 gene

FULL NAME: GINS complex subunit 3 (Psf3 homolog)


OTHER NAME(S):
FLJ13912
PSF3


DESCRIPTION:
This gene encodes a protein subunit of the GINS heterotetrameric complex, which is essential for the initiation of DNA replication and replisome progression in eukaryotes. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]


Nucleic acid sequence

        10         20         30         40         50         60
atgtcagagg cttatttccg agtggagtcg ggtgcgctgg ggcctgagga gaactttctt
        70         80         90        100        110        120
tctttggacg acatcctgat gtcccacgag aagctgccgg tgcgcacgga gaccgccatg
       130        140        150        160        170        180
cctcgccttg gcgctttctt cctggagcgg agcgcaggcg ccgagactga caacgcggtc
       190        200        210        220        230        240
ccacagggtt ttgctctgtt gcccaggctg gagtgcagtg gtgtgatatg gctcactgca
       250        260        270        280        290        300
gccttgacct cccaggctcc agagatcctc ccacctcagc cacctatgtg gctggtattg
       310        320        330        340        350        360
cagggttcca agcttgaact acccttgtgg ctggcaaaag gactttttga caacaagcga
       370        380        390        400        410        420
cggatccttt ctgtggaact ccccaagatc taccaagagg gttggaggac tgtgttcagt
       430        440        450        460        470        480
gcagatccca atgtggtgga cctccacaaa atggggcccc atttctacgg gtttggctcc
       490        500        510        520        530        540
cagctcctgc attttgacag tcccgagaat gcagacattt cccagtctct gctgcagact
       550        560        570        580        590        600
tttatcggac gttttcgccg catcatggac tcctcacaga atgcttacaa cgaagacact
       610        620        630        640        650        660
tcagccctgg tagccaggct agacgagatg gagaggggct tatttcaaac agggcagaaa
       670        680        690        700        710        720
ggactgaatg actttcagtg ttgggagaag gggcaggctt ctcagatcac agcttccaac
       730        740        750        760
ctcgttcaga attacaagaa gagaaaattc actgatatgg aagactga 

Last modification date: Oct. 2, 2011