Drosophila melanogaster Meigen (fruit fly) [DME]

FULL NAME: Replication factor C subunit 2


DESCRIPTION:
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Subunit 2 binds ATP.

STRUCTURE SIMILARITY:
Belongs to the activator 1 small subunits family.


RELATED PATHWAY(S):
DNA replication
nucleotide excision repair (NER)
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MPEEPEKTAD DKRSHLPWIE KYRPVKFKEI VGNEDTVARL SVFATQGNAP NIIIAGPPGV
        70         80         90        100        110        120
GKTTTIQCLA RILLGDSYKE AVLELNASNE RGIDVVRNKI KMFAQQKVTL PRGRHKIVIL
       130        140        150        160        170        180
DEADSMTEGA QQALRRTMEI YSSTTRFALA CNTSEKIIEP IQSRCAMLRF TKLSDAQVLA
       190        200        210        220        230        240
KLIEVAKWEK LNYTEDGLEA IVFTAQGDMR QGLNNLQSTA QGFGDITAEN VFKVCDEPHP
       250        260        270        280        290        300
KLLEEMIHHC AANDIHKAYK ILAKLWKLGY SPEDIIANIF RVCKRINIDE HLKLDFIREI
       310        320        330
GITHMKIIDG INSLLQLTAL LAKLCIAAEK H  

Encoded by RfC4 gene

FULL NAME: Replication factor C subunit 4


OTHER NAME(S):
154910_at
BEST:GH24992
CG14999
Dmel\CG14999
DmRFC4
l(3)64Ai
l(3)A1
l(3)dsl-1
l(3)dsl1
l(3)e20
l(3)Rfc4
l(3)rfc40
l(3)SG13
l(3)SH17
rfc
rfc4
Rfc4
rfc40
Rfc40
RfC40
rfc[40]


Nucleic acid sequence

        10         20         30         40         50         60
atgccggaag aaccagagaa aacggcggac gacaagcgca gtcacttgcc gtggattgag
        70         80         90        100        110        120
aagtaccgcc ccgtgaagtt caaggagata gtgggcaatg aggataccgt agcaagacta
       130        140        150        160        170        180
tccgtattcg ccacccaggg aaatgcaccc aatattatta ttgctggtcc tcctggcgtg
       190        200        210        220        230        240
ggcaagacaa ccaccatcca gtgtctggcc aggattctcc tgggagacag ctacaaggag
       250        260        270        280        290        300
gctgtcctcg agctgaatgc ctccaatgaa cgaggaatcg atgtggtccg caacaagatc
       310        320        330        340        350        360
aagatgtttg ctcagcagaa ggtgacactg ccgcggggca ggcacaagat tgtgattctg
       370        380        390        400        410        420
gacgaggcgg acagcatgac ggagggtgcc cagcaggcac tgcgccggac catggagatc
       430        440        450        460        470        480
tacagcagca ccactcgttt tgccctggcc tgcaacacca gcgagaagat catagagcct
       490        500        510        520        530        540
atccagtccc gctgcgccat gctacgattc accaagctgt ccgatgcgca agttctggcc
       550        560        570        580        590        600
aagctcatcg aggtggccaa gtgggagaag cttaactaca cggaggacgg acttgaggcc
       610        620        630        640        650        660
atcgtattca ctgcccaagg tgatatgcga cagggactga acaacctgca gtccaccgct
       670        680        690        700        710        720
cagggatttg gcgacatcac cgctgagaac gtctttaagg tctgcgacga gccgcaccca
       730        740        750        760        770        780
aagctcctag aggagatgat ccaccattgc gctgctaacg acatacacaa ggcctacaaa
       790        800        810        820        830        840
atcctggcca agctgtggaa gctgggatac tcgccggagg acatcattgc gaacatattc
       850        860        870        880        890        900
cgtgtctgca agcgcatcaa catcgatgag catttgaagc tggactttat ccgtgagatc
       910        920        930        940        950        960
ggaatcaccc acatgaagat tatcgatggt atcaactcgc tgctgcagct caccgccctt
       970        980        990
ctggccaaac tctgcattgc cgccgagaag cattag  

Last modification date: Oct. 2, 2011