Drosophila melanogaster Meigen (fruit fly) [DME]

FULL NAME: Proliferating cell nuclear antigen


DESCRIPTION:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity).

STRUCTURE SIMILARITY:
Belongs to the PCNA family.


RELATED PATHWAY(S):
DNA replication
base excision repair (BER)
nucleotide excision repair (NER)
mismatch repair (MMR)


Amino acids sequence

        10         20         30         40         50         60
MLEARLSQTL LLKKIVDALK EIIAQGTLDC SENGLELQSM DNSHVSLVAL SLASDCFEKF
        70         80         90        100        110        120
HCDRNVSLGL DLKSLGKVLK CANSDDAVTI KAVDRPEKIT LSFESDGKER TADYELKLLN
       130        140        150        160        170        180
LDQDHMEIPK KDYTCFIQLP SSEFARICRD MSMFDESLTI ACSSKGIRFL AKGDLGTANI
       190        200        210        220        230        240
QLSAGTAMDV SIEVQEPVTQ SFAGRYLNTF TKATPLADRV KLYLSDERPL LVEYPIEDYG
       250
HIRYYLAPKV NDPDF    

Encoded by CG10262 gene


OTHER NAME(S):
Dmel\CG10262
PCNA2


Nucleic acid sequence

        10         20         30         40         50         60
atgctcgagg cgcgtttgag tcagactttg ctgctgaaga agatcgtcga tgcactaaag
        70         80         90        100        110        120
gaaatcatcg cccagggaac gctggactgc agtgaaaatg gtctggagct gcaatcgatg
       130        140        150        160        170        180
gacaactccc acgtttcgct ggtggcccta agtctggctt cggattgttt tgaaaagttt
       190        200        210        220        230        240
cactgcgatc gcaatgtctc gctgggcttg gatctgaaat ccctgggcaa ggtgcttaag
       250        260        270        280        290        300
tgcgccaata gcgacgatgc ggtcaccatt aaggccgttg acagaccgga gaagattacg
       310        320        330        340        350        360
ctcagcttcg agtcggatgg caaggagcgc acggcggact acgagctgaa gctcctcaat
       370        380        390        400        410        420
ctggaccagg atcacatgga gattccgaaa aaggactaca cctgcttcat ccagttgccg
       430        440        450        460        470        480
tcgtcagagt tcgcgcgcat ttgccgggac atgagcatgt tcgacgagtc cctgacgatc
       490        500        510        520        530        540
gcctgctcct cgaagggcat caggttcttg gccaagggag atctgggcac ggccaacatt
       550        560        570        580        590        600
cagctgagtg cgggcaccgc catggacgtg agcattgagg tgcaggagcc cgtgacccag
       610        620        630        640        650        660
tccttcgccg gtcgctacct caacaccttc accaaggcca ctccgctggc agatcgcgtc
       670        680        690        700        710        720
aagctctacc tgtccgacga gcggccactc ctggtggagt atcccatcga ggattacggc
       730        740        750        760
cacattcgat actaccttgc acccaaggtg aatgaccccg atttctag 

Last modification date: Oct. 7, 2011