Drosophila melanogaster Meigen (fruit fly) [DME]

FULL NAME: Replication protein A 70 kDa DNA-binding subunit


DESCRIPTION:
Participates in a very early step in DNA replication. RP-A is a single-stranded DNA-binding protein.

STRUCTURE SIMILARITY:
Belongs to the replication factor A protein 1 family.


RELATED PATHWAY(S):
DNA replication
nucleotide excision repair (NER)
mismatch repair (MMR)
homologous recombination (HR)
Fanconi anemia (FA) pathway


Amino acids sequence

        10         20         30         40         50         60
MVLASLSTGV IARIMHGEVV DAPVLQILAI KKINSAADSE RYRILISDGK YFNSYAMLAS
        70         80         90        100        110        120
QLNVMQHNGE LEEFTIVQLD KYVTSLVGKD GAGKRVLIIS ELTVVNPGAE VKSKIGEPVT
       130        140        150        160        170        180
YENAAKQDLA PKPAVTSNSK PIAKKEPSHN NNNNIVMNSS INSGMTHPIS SLSPYQNKWV
       190        200        210        220        230        240
IKARVTSKSG IRTWSNARGE GKLFSMDLMD ESGEIRATAF KEQCDKFYDL IQVDSVYYIS
       250        260        270        280        290        300
KCQLKPANKQ YSSLNNAYEM TFSGETVVQL CEDTDDDPIP EIKYNLVPIS DVSGMENKAA
       310        320        330        340        350        360
VDTIGICKEV GELQSFVART TNKEFKKRDI TLVDMSNSAI SLTLWGDDAV NFDGHVQPVI
       370        380        390        400        410        420
LVKGTRINEF NGGKSLSLGG GSIMKINPDI PEAHKLRGWF DNGGGDSVAN MVSARTGGGS
       430        440        450        460        470        480
FSTEWMTLKD ARARNLGSGD KPDYFQCKAV VHIVKQENAF YRACPQSDCN KKVVDEGNDQ
       490        500        510        520        530        540
FRCEKCNALF PNFKYRLLIN MSIGDWTSNR WVSSFNEVGE QLLGHTSQEV GEALENDPAK
       550        560        570        580        590        600
AEQIFSALNF TSHIFKLRCK NEVYGDMTRN KLTVQSVAPI NHKEYNKHLL KELQELTGIG

SSN     

Encoded by RpA-70 gene

FULL NAME: Replication Protein A 70


OTHER NAME(S):
CG9633
D-RPA70
D-SSB
Dmel\CG9633
DmRPA
dmrpa1
dRP-A
DRP-A
i164
RP-A
RPA
RPA 70
Rpa-70
RPA1
RpA70
RPA70
Ssb-70


Nucleic acid sequence

        10         20         30         40         50         60
atggtcctgg catctttgtc cactggtgtg attgctcgca ttatgcatgg cgaggttgtg
        70         80         90        100        110        120
gatgccccgg ttctccagat cctggcaatc aagaagatta acagcgcagc ggactcagag
       130        140        150        160        170        180
cgctatcgca tcctaatctc cgacggcaag tactttaaca gctatgcgat gctggccagt
       190        200        210        220        230        240
cagctgaacg tgatgcagca caatggagaa ttagaggagt tcaccattgt ccagctagat
       250        260        270        280        290        300
aaatatgtga cctcactggt aggcaaggac ggagccggaa aacgcgttct catcatttcc
       310        320        330        340        350        360
gaactaactg tggtgaatcc tggcgccgag gttaagtcca aaattggcga acccgttacg
       370        380        390        400        410        420
tatgaaaatg cagccaagca ggatctggcg cctaagccag cagtaacatc taattccaag
       430        440        450        460        470        480
ccaattgcca aaaaggaacc gagccacaac aacaataata acatagtaat gaattcctct
       490        500        510        520        530        540
attaatagtg gaatgacaca tcccatttct agcctaagtc cctaccaaaa taagtgggtg
       550        560        570        580        590        600
attaaggctc gcgtgacctc aaaatccggc attcgcacct ggagcaatgc ccgcggcgag
       610        620        630        640        650        660
ggcaagttgt tcagcatgga tttaatggac gaatcgggcg aaattcgggc cactgccttc
       670        680        690        700        710        720
aaggaacagt gcgataagtt ctacgacctc attcaagtgg atagcgtgta ctatatatca
       730        740        750        760        770        780
aagtgtcaat tgaaaccggc aaacaagcag tactcttcgc tgaacaacgc ctacgagatg
       790        800        810        820        830        840
actttttccg gtgaaacagt tgtccagctt tgtgaggata ccgacgatga tcccataccg
       850        860        870        880        890        900
gaaattaagt acaaccttgt tcctatttcc gatgtgtcgg gtatggaaaa taaagcagcg
       910        920        930        940        950        960
gtagacacaa taggaatttg caaggaggtg ggcgagttgc aatcattcgt agctcgcacc
       970        980        990       1000       1010       1020
acaaacaagg aattcaagaa acgggacata accctagtgg acatgagtaa ctcggccatc
      1030       1040       1050       1060       1070       1080
agcttgaccc tttgggggga tgatgccgtt aactttgacg gtcatgtgca gcctgtgatc
      1090       1100       1110       1120       1130       1140
ctggtcaagg gaacacgcat taacgagttc aatggcggaa agtccttgag cctcggcggt
      1150       1160       1170       1180       1190       1200
ggctcaatca tgaagattaa ccccgatata cccgaggcac ataagctgcg cggctggttc
      1210       1220       1230       1240       1250       1260
gacaatggag gtggtgacag tgtcgccaat atggtttcgg cgcgaacggg cggaggaagc
      1270       1280       1290       1300       1310       1320
ttctctactg aatggatgac gcttaaggat gcgcgggctc gcaatctcgg cagcggcgac
      1330       1340       1350       1360       1370       1380
aagcctgatt acttccagtg caaggcagtg gtgcacattg tcaaacagga aaatgctttc
      1390       1400       1410       1420       1430       1440
taccgagcct gccctcagag cgactgcaac aagaaggttg tcgatgaggg caacgaccag
      1450       1460       1470       1480       1490       1500
ttccgctgcg agaaatgtaa cgcactgttt cccaacttta agtaccgact gctgatcaac
      1510       1520       1530       1540       1550       1560
atgagcatcg gggactggac ttccaaccgt tgggtcagca gttttaacga ggtcggtgaa
      1570       1580       1590       1600       1610       1620
cagcttctcg ggcacacttc gcaggaagtg ggtgaggccc ttgagaacga ccctgccaaa
      1630       1640       1650       1660       1670       1680
gccgagcaga ttttctcagc actcaacttc acttcacaca tctttaagct gcgctgcaag
      1690       1700       1710       1720       1730       1740
aacgaggttt acggggacat gactcgcaac aagctcactg tgcagtctgt agcccctatc
      1750       1760       1770       1780       1790       1800
aatcacaagg agtacaataa gcacttgctc aaggagctgc aggagctaac cggcattggc
      1810
tcatcaaact ga    

Last modification date: Oct. 2, 2011