Drosophila melanogaster Meigen (fruit fly) [DME]

FULL NAME: DNA polymerase delta small subunit


DESCRIPTION:
The function of the small subunit is not yet clear.

STRUCTURE SIMILARITY:
Belongs to the DNA polymerase delta/II small subunit family.


CATALYTIC ACTIVITY:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


RELATED PATHWAY(S):
DNA replication
base excision repair (BER)
nucleotide excision repair (NER)
mismatch repair (MMR)
homologous recombination (HR)


Amino acids sequence

        10         20         30         40         50         60
MTNRLETKYE NLSSIFRLKG HDYQKQFFHL YAHRLAEMTR LLTPLAQKKW GNKEPIKKLC
        70         80         90        100        110        120
ELRGEQDVHC ILIGTIFKHQ AHKPSILRDI SEENQLAPQP PRQNYSDPED KIVLEDELQR
       130        140        150        160        170        180
VRLQGKLNGQ LLATGVVCAA LGGTDSDGFF NVEDILFYES GPQKPLAPIK RSRLLVLASG
       190        200        210        220        230        240
LDQLQAHKFV EALNLFQYWL AGSLGNNKEA GSMVRLIVAG NSVRASAMAH VPTLQVARTQ
       250        260        270        280        290        300
ANANDTVQAV SQLDQWFASW ARSLPVDIMP GPYDPANFML PQQPFHKCMF PQAAQLATFQ
       310        320        330        340        350        360
AVTNPYSCRL DEALVVGTSG QNVSDLLRST SLDSALEALR CTLTWGHVAP TAPDTLACYP
       370        380        390        400        410        420
YIESDPFILR ECPHVYYAGN CESFATELHE GSEGKRTRLV CVPSFSKTQS VAVVDLDTLD
       430
CRMVNFSVDA E    

Encoded by CG12018 gene


OTHER NAME(S):
12018
BcDNA:HL03874
Dmel\CG12018


Nucleic acid sequence

        10         20         30         40         50         60
atgaccaacc gcctggagac caaatacgag aacctgagca gcattttccg gctaaaggga
        70         80         90        100        110        120
catgactacc aaaagcagtt cttccatctg tatgcccacc gcctggccga gatgacgcgt
       130        140        150        160        170        180
ctcctaacgc cgctggccca gaagaagtgg ggcaacaagg agcccatcaa aaaactgtgt
       190        200        210        220        230        240
gagctgcggg gtgaacagga cgtgcactgc atcctgatcg gcaccatttt taagcaccag
       250        260        270        280        290        300
gctcacaagc ccagtatcct ccgggacatt tctgaggaga atcagttagc gccacagccg
       310        320        330        340        350        360
ccaagacaga actactcgga tccggaggac aagattgttc tggaggatga actgcagcgg
       370        380        390        400        410        420
gttcgacttc agggcaagct aaatggacag ctcttagcca ctggagttgt gtgcgctgcc
       430        440        450        460        470        480
ctcggtggaa cagacagtga cggatttttt aacgtggagg atatactctt ctacgaaagt
       490        500        510        520        530        540
ggacctcaga agccactggc ccccattaaa agaagccgcc tcctggtgct ggcgtctggg
       550        560        570        580        590        600
ttggaccaac tgcaggccca caaatttgtg gaggcattga atctctttca gtactggctg
       610        620        630        640        650        660
gccggcagtc ttggaaacaa caaggaagcg ggctccatgg tgcgtcttat cgtggctgga
       670        680        690        700        710        720
aactcggtga gagccagtgc catggcacat gtgcccaccc tacaggtggc acgcacccag
       730        740        750        760        770        780
gcgaacgcaa atgacacagt ccaggccgtt tcccagctag accagtggtt tgcctcatgg
       790        800        810        820        830        840
gcacgcagtc tgcccgtcga cataatgccg ggaccctacg acccggccaa ctttatgctg
       850        860        870        880        890        900
ccccagcagc cgttccacaa gtgcatgttt ccccaggctg ctcaactggc aactttccag
       910        920        930        940        950        960
gcggtgacta atccgtacag ctgccggctg gatgaggccc tggtggtagg cacatctggc
       970        980        990       1000       1010       1020
cagaatgtat cggatctgtt gcgcagcact tcgctggact cggcgctgga ggcccttcgc
      1030       1040       1050       1060       1070       1080
tgcaccctca cctggggaca tgttgctccc actgcaccgg acactctagc gtgctacccg
      1090       1100       1110       1120       1130       1140
tacatcgaaa gtgatccctt catcctgcgc gagtgtccgc acgtttacta cgccggcaac
      1150       1160       1170       1180       1190       1200
tgcgagtcgt ttgcgaccga gctgcacgag ggttccgaag gcaagcgcac ccgcctagtc
      1210       1220       1230       1240       1250       1260
tgcgtgccca gttttagcaa aacacagagt gtggccgtcg ttgacctgga tacgctggat
      1270       1280       1290
tgccgcatgg tcaactttag cgtagatgca gaataa  

Last modification date: Oct. 2, 2011