Drosophila melanogaster Meigen (fruit fly) [DME]

FULL NAME: DNA primase large subunit


DESCRIPTION:
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. Plays a role in the fat facets (faf)-dependent cell-communications pathway.

STRUCTURE SIMILARITY:
Belongs to the eukaryotic-type primase large subunit family.


RELATED PATHWAY(S):
DNA replication


Amino acids sequence

        10         20         30         40         50         60
MEFGLKKRAR HEVKVEVASL ETKYPHNVML YHYPPTEDVH IDEFEELALE RLRLLRVLDR
        70         80         90        100        110        120
ASTRNLRVLS DEWKEIVSAD LTREGLRSYL RLCSTGGSAK HEADIQTRRR DYLSHFILRL
       130        140        150        160        170        180
AYCRSEDLAR WFVAREMELF RYKFAALSSF EVKQFLEANG FEIHPLTEAQ KDEVKDGLYE
       190        200        210        220        230        240
STVGQSVAKI ELLDFYKVPF TQVLDLVRGR RCFLKAGYAY VNTHDLVSLV GTKQQDEIEQ
       250        260        270        280        290        300
GLQAAKTMVE DVEADERISR TLKALHNSYT GRDYTVCRDA AVPIESLDQL SKTSMPLCMR
       310        320        330        340        350        360
MCHEHIRANH HIKHSGRMQY GLFLKGIGVA LEDSLRFWRE EFTKKMDADK FTRSYEYNIY
       370        380        390        400        410        420
HNYGKKGSMV NYTPYSCAKI IKDVAGPGDC HGCPYKNMDQ GSLKTKLSSY GLSASAIDEV
       430        440        450        460        470        480
MFFVSRGHYQ IGCGKYFQLT HNSPVEPSIN HPNNYFEESQ IAMGNRQKRA NGSAPPKARI
       490        500        510        520        530
RPDIKGHGDR SMLMGDDDDE LWRIAETQER IMQSQKDISE AFNDDLDLTQ IDY

Encoded by DNApol-alpha60 gene

FULL NAME: DNA polymerase alpha 60kD


OTHER NAME(S):
BcDNA:GM13640
CG5553
Dmel\CG5553
Dmpol alpha
DNA polalpha
DNAprim
DNAprimase
GM13640
l(3)77ABe
l(3)j10B2
Pol
pol alpha
S(faf)240


Nucleic acid sequence

        10         20         30         40         50         60
atggagtttg gtctgaagaa acgcgcgaga catgaggtga aggtggaggt ggccagcctg
        70         80         90        100        110        120
gaaaccaagt acccgcacaa cgtcatgctg taccactatc cgccgacgga ggacgtgcac
       130        140        150        160        170        180
atagacgaat tcgaggagct ggctctagag cgcttgcgcc ttctccgcgt cctggatcgc
       190        200        210        220        230        240
gcaagcaccc ggaacctgcg cgtgctctca gatgaatgga aggaaatcgt gagtgcggac
       250        260        270        280        290        300
ctgacccgcg agggattgcg cagctattta aggctctgct ccaccggcgg aagcgccaag
       310        320        330        340        350        360
cacgaggcgg atatccagac ccgcaggcgg gactatcttt cgcacttcat cttgcggctg
       370        380        390        400        410        420
gcctactgcc gctccgagga ccttgcgcgc tggttcgtgg cccgcgaaat ggagctcttc
       430        440        450        460        470        480
cggtacaaat tcgctgcact tagcagcttc gaggtgaagc agttccttga ggccaacggc
       490        500        510        520        530        540
tttgagattc accccctcac cgaggcccag aaggacgaag tcaaggacgg cctgtacgag
       550        560        570        580        590        600
agcacggtcg gacagagcgt ggcgaagatc gagctgttgg acttctacaa ggtgcccttc
       610        620        630        640        650        660
acccaggtgc tcgatctggt gcgcggacgt cgctgctttt taaaggctgg ctacgcctat
       670        680        690        700        710        720
gttaacaccc acgacctggt gtccctagtg ggcaccaagc agcaggacga gatcgagcaa
       730        740        750        760        770        780
ggcctgcagg ctgctaagac tatggtggag gatgtagaag ccgacgagcg catctcccgc
       790        800        810        820        830        840
acacttaaag ctctacataa ctcgtatacc ggtagggatt acaccgtttg tcgggatgca
       850        860        870        880        890        900
gctgtgccca tcgagtcgct cgatcagctc tccaagacct ccatgccgtt gtgtatgcgc
       910        920        930        940        950        960
atgtgccacg agcacattcg tgccaaccat cacataaaac atagcggccg aatgcaatac
       970        980        990       1000       1010       1020
ggcctgtttc tcaaaggaat tggcgtggca ctggaggatt cgctgcgctt ctggcgcgaa
      1030       1040       1050       1060       1070       1080
gagtttacca agaaaatgga cgcggataag tttacacgca gctacgagta caatatttac
      1090       1100       1110       1120       1130       1140
cataactacg gaaagaaggg ttccatggtc aactacacac cctactcgtg cgccaagatt
      1150       1160       1170       1180       1190       1200
atcaaggatg tggcggggcc gggcgattgc cacggctgtc cgtataagaa catggatcag
      1210       1220       1230       1240       1250       1260
ggctcgttga aaaccaagct gtcctcctat ggcctgtcag ccagtgccat cgacgaggtg
      1270       1280       1290       1300       1310       1320
atgttctttg tgtcccgcgg tcactatcaa attggatgcg gcaagtactt ccaacttacc
      1330       1340       1350       1360       1370       1380
cacaattcac ccgtcgagcc gagcatcaat caccccaaca actacttcga ggagagccag
      1390       1400       1410       1420       1430       1440
atagcgatgg gcaaccggca gaagcgcgcc aatggttctg ctccgcccaa ggccagaatc
      1450       1460       1470       1480       1490       1500
cgtccagata tcaagggcca tggggatcgg tccatgctga tgggtgacga tgacgatgag
      1510       1520       1530       1540       1550       1560
ttgtggcgaa tcgcggaaac ccaggagcgt atcatgcaga gccaaaagga catatccgag
      1570       1580       1590       1600
gccttcaatg atgatctaga tcttacgcaa atcgattact aa 

Last modification date: Oct. 2, 2011